CD 항원(CD antigen)
From Opengenome.net
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
CD1a, b, c, d, e | 43-49 | MHC class I-like structure | Dendritic cells, B cells, Langerhans cells, some thymocytes | Display of non-peptide and glycolipid antigens for T-cell responses |
CD2 | 45-58 | LFA-2, T11, E-rosette receptor; CD58 binding adhesion molecule | T cells, thymocytes, NK cells | Adhesion molecule involved in T-cell activation |
CD3 | γ;25-28δ; 20ε; 20 |
T3; composed of 3 polypeptide chains: γ, δ, ε | Thmocytes, T cells, NK1-T cells | Essential role in TCR signal transduction and in cell-surface expression of the TCR |
CD4 | 55 | L3T4 | MHC class Ⅱ-restricted T cells, some thymocytes, monocytes/macrophage, granulocytes | Co-receptor for MHC class Ⅱ-restricted T-cell activation; thymic differentiation marker for T cells; receptor for HIV |
CD5 | 58 | Leu1, T1, Ly-1 | Mature T cells, early thymocytes; small amounts on a subset of mature B cells (B1a B cells) | Positive or negative modulation of TCR and BCR signaling, depending on the type and developmental stage of cell displaying it |
CD6 | 105 or 130 | T12 | Most peripheral T cells, thumocytes, a subset of B cells | Adhesion molecule that binds developing thymocytes to thymic epitheral cells; possible co-stimulatory molecule for mature T cells |
CD7 | 40 | gp-40 | Pluripotent hematopoetic cells, T cells, thymocytes | Not known |
CD8 | T8, Leu-22 ; a membrane-bound dimer of two chains; αβ heterodimer or αα homodimer | MHC class Ⅰ-restricted T cells, some thymocytes | Coreceptor for MHC class Ⅰ-restricted T cells | |
CD9 | 24 | MRP-1, p24 | Platelets, early B cells, activated B cells, activated T cells, eosinophils, basophils | Modulation of cell adhesion and migration; trigger of platelet activation |
CD10 | 100 | Common acute lymphoblastic leukemia antigen (CALLA), EC 3.4.24.11 (neprilysin), enkephalinase, gp100, neutral endopeptidase (NEP), metalloendopeptidase | B-cell precursors, T-cell precursors, bone-marrow stromalcells | Protease |
CD 항원 (CD antigen) |
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CD1-15 | CD16-30 | CD31-45 | CD46-60 | CD61-75 | CD76-90 | CD91-105 |
CD106-120 | CD121-134 | CD135-149 | CD150-164 | CD165-179 | CD180-194 | CD195-200 |