CD91-105

From Opengenome.net

 CD antigen

 MW.(kDa) 

 Synonyms & Properties

 Leukocyte expression  

 Function

 CD91  515, 85  α-2 macroglobulin receptor (ALPHA2M-R), low density lipoprotein-receptor-related protein (LRP)   Monocytes, many non-hematopoeitic cells  2-macroglobulin receptor 
 CDw92  70  GR9   Monocytes, granulocytes, peripheral blood lymphocytes (PBL)    Not known 
 CDw93  110  GR11   Monocytes, granulocytes, endothelial cells   Not known 
 CD94  70  Kp43; forms complex with NKG2-A (which contains cytoplasmic immunoreceptor tyrosine-based inhibition motifs)   NK cells, subsets of CD8+ αβ and γδ T cells   Subunit of complex with NKG2-A that is involved in inhibition of NK cells 
 CD95  45, 90, >/200  APO-1, Fas antigen (Fas)   Activated T and B cells   Mediation of apoptosis-inducing signals 
 CD96  160  T-cell activation increased late expression (TACTILE)   Activated T cells, NK cells  Not known 
 CD97  75-85  BL-KDD/F12   Activated B and T cells, monocytes, granulocytes  Binding to CD55
 CD98  125  4F2, FRP-1, RL-388 in mouse   Not hemaopoeitic specific; activated and transformed cells; lower levels on quiescent cells   Role in regulation of cellular activation 
 CD99  32  CD99R (epitope restricted to subset of CD99 molecules), E2, MIC2 gene product   Peripheral-blood lymphocytes, thymocytes   Not known 
 CD100  300, 120     Most hematopoeitic cells except immature bone-marrow cells, RBCs, and platelets; activated T cells, germinal-center B cells  Promotion of T-cell activation and adhesion
 CD101  240  P126, V7  Monocytes, granulocytes, dendritic cells, activated T cells  Possible role in T-cell activation 
 CD102  55-65  Intercellular adhesion molecule-2 (ICAM-2)   Vascular endothelial cells, monocytes, platelets, some populations of resting lymphocytes   Co-stimulation of immune responses; lymphocyte recirculation 
 CD103  175  HML-1, integrin αE chain   Intraepithelial lymphocytes (in tissues such as intestine, bronchi, inflammatory skin/breast/salivary glands), many laminapropria T cells, some lymphocytes in peripheral blood and peripheral lymphoid organs   Role in the issue-specific retention of lymphocytes at basolateral surface of intestinal spithelial cells; possible accessary molecule for activation of intraepithelial lymphocytes 
 CD104  220  β4 integrin chain, tumor-specific protein 180 antigen (TSP-180) in mouse   CD4 CD8 thymocytes, neuronal, epithelial, and some endothelial cells, Schwann cells, trophoblasts   Integrin that associates with CD49f, binds laminins 
 CD105  180  Endoglin   Endothelial cells of small and large cessels, activated monocytes and tissue macrophages, stromal cells of certain tissues including bone precursors in fetal and adult bone marrow, syncytiotrophoblast throughout pregnancy and cytotrophoblasts transiently during first trimester   Modulator of cellular responses to TGF-β1