CD91-105
From Opengenome.net
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
CD91 | 515, 85 | α-2 macroglobulin receptor (ALPHA2M-R), low density lipoprotein-receptor-related protein (LRP) | Monocytes, many non-hematopoeitic cells | 2-macroglobulin receptor |
CDw92 | 70 | GR9 | Monocytes, granulocytes, peripheral blood lymphocytes (PBL) | Not known |
CDw93 | 110 | GR11 | Monocytes, granulocytes, endothelial cells | Not known |
CD94 | 70 | Kp43; forms complex with NKG2-A (which contains cytoplasmic immunoreceptor tyrosine-based inhibition motifs) | NK cells, subsets of CD8+ αβ and γδ T cells | Subunit of complex with NKG2-A that is involved in inhibition of NK cells |
CD95 | 45, 90, >/200 | APO-1, Fas antigen (Fas) | Activated T and B cells | Mediation of apoptosis-inducing signals |
CD96 | 160 | T-cell activation increased late expression (TACTILE) | Activated T cells, NK cells | Not known |
CD97 | 75-85 | BL-KDD/F12 | Activated B and T cells, monocytes, granulocytes | Binding to CD55 |
CD98 | 125 | 4F2, FRP-1, RL-388 in mouse | Not hemaopoeitic specific; activated and transformed cells; lower levels on quiescent cells | Role in regulation of cellular activation |
CD99 | 32 | CD99R (epitope restricted to subset of CD99 molecules), E2, MIC2 gene product | Peripheral-blood lymphocytes, thymocytes | Not known |
CD100 | 300, 120 | Most hematopoeitic cells except immature bone-marrow cells, RBCs, and platelets; activated T cells, germinal-center B cells | Promotion of T-cell activation and adhesion | |
CD101 | 240 | P126, V7 | Monocytes, granulocytes, dendritic cells, activated T cells | Possible role in T-cell activation |
CD102 | 55-65 | Intercellular adhesion molecule-2 (ICAM-2) | Vascular endothelial cells, monocytes, platelets, some populations of resting lymphocytes | Co-stimulation of immune responses; lymphocyte recirculation |
CD103 | 175 | HML-1, integrin αE chain | Intraepithelial lymphocytes (in tissues such as intestine, bronchi, inflammatory skin/breast/salivary glands), many laminapropria T cells, some lymphocytes in peripheral blood and peripheral lymphoid organs | Role in the issue-specific retention of lymphocytes at basolateral surface of intestinal spithelial cells; possible accessary molecule for activation of intraepithelial lymphocytes |
CD104 | 220 | β4 integrin chain, tumor-specific protein 180 antigen (TSP-180) in mouse | CD4 CD8 thymocytes, neuronal, epithelial, and some endothelial cells, Schwann cells, trophoblasts | Integrin that associates with CD49f, binds laminins |
CD105 | 180 | Endoglin | Endothelial cells of small and large cessels, activated monocytes and tissue macrophages, stromal cells of certain tissues including bone precursors in fetal and adult bone marrow, syncytiotrophoblast throughout pregnancy and cytotrophoblasts transiently during first trimester | Modulator of cellular responses to TGF-β1 |