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CD121-135

Revision as of 17:26, 11 September 2006 by Ihjung (talk | contribs)

 CD antigen

 MW.(kDa) 

 Synonyms & Properties

 Leukocyte expression  

 Function

 CD121a  80  IL-1R, IL-1R type 1, type 1 IL-1R   Thymocytes, T cells   Type Ⅰ interleukin-1 receptor 
 CDw121b  60-70  Il-1R type2, type2 IL-1R   B cells, macrophages, monocytes    Type Ⅰ interleukin-1 receptor 
 CD122  70-75  Interleukin-2 receptor β chain (IL-2Rβ)  T cells, B cells, NK cells, monocytes/macrophages   Critical component of IL-2-and IL-15-mediated signaling
 CD123  70  IL-3 receptor α subunit (IL-3Rα)   Bone-marrow stem cells, granulocytes, monocytes, megakaryocytes   IL-3 receptor chain 
 CD124  140  IL-4R   Hematopoeitiv and non-hematopoeitic cells   Receptor subunit of IL-4 and IL-113 
 CDw125  60  IL-5Rα   Eosinophils, activated B cells, basophils   Low-affinity receptor for IL-5; α chain of IL-5 receptor 
 CD126  80  Interleukin-6 receptor (IL-6R); associates with CD130   T cells, monocytes, activated B cells, hepatocytes and some other non-hematopoeitic cells   Receptor for IL-6 
 CD127        
 CDw128a        
 CDw128b        
 CD130        
 CDw131        
 CD132        
 CD134        
 CD135