Difference between revisions of "SCOP"
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| − | <p>SCOP (Structural Classification of Proteins)</p> | + | <p><font color="#800080" size="4"><strong>SCOP (Structural Classification of Proteins)</strong></font></p> |
| − | <p>SCOP은 | + | <p>SCOP은 [[PDB]]에 수록되어져 있는 3D 구조를 체계적으로 분석한 database로서, 수록되어진 [[database]]를 구조적인 특징에 따라서 10개의 <br />class로 분류하고 있다. 각각의 class는 2D 구조로 구성되어져 있고, [[topology]]에 의해 fold로 다시 누뉘고 있다. fold는 다시 [[superfamily]]와 <br />[[family]], [[domain]]으로 하위 분류가 이루어지며 [[단백질]] 구조의 [[계통 분석학]]적 분석이 체계적으로 이루어져 있다. </p> |
| − | <p># Site<br /><a href="http://scop.mrc-lmb.cam.ac.uk/scop/">http://scop.mrc-lmb.cam.ac.uk/scop/</a><br /><a href="http://scop.mrc-lmb.cam.ac.uk/scop/I/scop_logo_small.gif">http://scop.mrc-lmb.cam.ac.uk/scop/I/scop_logo_small.gif</a></p> | + | <p><font color="#99cc00"><strong># Site</strong></font><br /><a href="http://scop.mrc-lmb.cam.ac.uk/scop/">http://scop.mrc-lmb.cam.ac.uk/scop/</a><br /><a href="http://scop.mrc-lmb.cam.ac.uk/scop/I/scop_logo_small.gif">http://scop.mrc-lmb.cam.ac.uk/scop/I/scop_logo_small.gif</a><br /><br /><strong><font color="#99cc00"># Paper</font></strong><br /><strong>Authors</strong>. Alexey G. Murzin, John-Marc Chandonia, Antonina Andreeva, Dave Howorth, Loredana Lo Conte, Bartlett G. Ailey, Steven E. Brenner, Tim J. P. Hubbard, and Cyrus Chothia. <a href="http://scop.mrc-lmb.cam.ac.uk/scop/mail.cgi">scop@mrc-lmb.cam.ac.uk</a> <br /><strong>Reference: </strong>Murzin A. G., Brenner S. E., Hubbard T., Chothia C. (1995). <font size="-1">SCOP</font>: a structural classification of proteins database for the investigation of sequences and structures. <em>J. Mol. Biol.</em> 247, 536-540. [<a href="http://scop.mrc-lmb.cam.ac.uk/scop/ref/1995-jmb-scop.pdf">PDF</a>] <br /><strong>Recent changes</strong> are described in: Lo Conte L., Brenner S. E., Hubbard T.J.P., Chothia C., Murzin A. (2002). <font size="-1">SCOP</font> database in <font size="-1">2002</font>: refinements accommodate structural genomics. <a href="http://nar.oupjournals.org/cgi/content/full/30/1/264"><em>Nucl. Acid Res. </em>30(1), 264-267</a>. [<a href="http://scop.mrc-lmb.cam.ac.uk/scop/ref/nar2002.pdf">PDF</a>] and <br />Andreeva A., Howorth D., Brenner S.E., Hubbard T.J.P., Chothia C., Murzin A.G. (2004). <font size="-1">SCOP</font> database in <font size="-1">2004</font>: refinements integrate structure and sequence family data. <a href="http://nar.oupjournals.org/cgi/reprint/32/suppl_1/D226"><em>Nucl. Acid Res. </em>32:D226-D229</a>. [<a href="http://scop.mrc-lmb.cam.ac.uk/scop/ref/nar2004.pdf">PDF</a>]. </p> |
Latest revision as of 11:54, 17 August 2006
SCOP (Structural Classification of Proteins)
SCOP은 PDB에 수록되어져 있는 3D 구조를 체계적으로 분석한 database로서, 수록되어진 database를 구조적인 특징에 따라서 10개의
class로 분류하고 있다. 각각의 class는 2D 구조로 구성되어져 있고, topology에 의해 fold로 다시 누뉘고 있다. fold는 다시 superfamily와
family, domain으로 하위 분류가 이루어지며 단백질 구조의 계통 분석학적 분석이 체계적으로 이루어져 있다.
# Site
http://scop.mrc-lmb.cam.ac.uk/scop/
http://scop.mrc-lmb.cam.ac.uk/scop/I/scop_logo_small.gif
# Paper
Authors. Alexey G. Murzin, John-Marc Chandonia, Antonina Andreeva, Dave Howorth, Loredana Lo Conte, Bartlett G. Ailey, Steven E. Brenner, Tim J. P. Hubbard, and Cyrus Chothia. scop@mrc-lmb.cam.ac.uk
Reference: Murzin A. G., Brenner S. E., Hubbard T., Chothia C. (1995). SCOP: a structural classification of proteins database for the investigation of sequences and structures. J. Mol. Biol. 247, 536-540. [PDF]
Recent changes are described in: Lo Conte L., Brenner S. E., Hubbard T.J.P., Chothia C., Murzin A. (2002). SCOP database in 2002: refinements accommodate structural genomics. Nucl. Acid Res. 30(1), 264-267. [PDF] and
Andreeva A., Howorth D., Brenner S.E., Hubbard T.J.P., Chothia C., Murzin A.G. (2004). SCOP database in 2004: refinements integrate structure and sequence family data. Nucl. Acid Res. 32:D226-D229. [PDF].
