Changes

From Opengenome.net

CD31-45

1,873 bytes added, 23:07, 5 September 2006
no edit summary
<td>&nbsp;&alpha;&beta; dimer: &alpha;, 125; &beta;, 122&nbsp;</td>
<td>&nbsp;GlycoproteinⅡb (GPⅡb) &alpha;Ⅱb&nbsp;integrin chain; forms platelet fibrinogen receptor by association with GP Ⅲa&nbsp;</td>
<td>&nbsp;&nbsp;Platelets, megakaryocytes</td> <td>&nbsp;Subunit of platelet fibrinogen receptor, which mediates platelet aggregation by acting as receptor for fibrinogen; possibly also receptor for von Willebrand factor, fibronectin, and thrombospondin&nbsp;</td>
</tr>
<tr>
<td bgcolor="#cccccc"><strong>&nbsp;CD42a,b,c,d</strong></td>
<td bgcolor="#cccccc">&nbsp;a, 23;&nbsp;<br /> &nbsp;b, 135,23;&nbsp;<br /> &nbsp;c, 22;</td> <td bgcolor="#cccccc">&nbsp;a, GPIX; b, GPIb-&alpha;; c, GPIb-&beta;; d, GPV</td> <td bgcolor="#cccccc">&nbsp;Platelets, megakaryocytes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Adhesion of platelets to endothelium; amplification of platelet response to thrombin&nbsp;</td>
</tr>
<tr>
<td><strong>&nbsp;CD43</strong></td>
<td>&nbsp;95-115 in&nbsp;<br /> T cells, 115-135 in neutrophils</td> <td>&nbsp;gpL115, leukocyte sialoglycoprotein, leukosialin, sialophorin&nbsp;</td> <td>&nbsp;All leukocytes except most resting B cells&nbsp;</td> <td>&nbsp;Possible anti-adhesive (&quot;barrier&quot;) molecule mediating repulsion between leukocytes and other cells&nbsp;</td>
</tr>
<tr>
<td bgcolor="#cccccc"><strong>&nbsp;CD44</strong></td>
<td bgcolor="#cccccc">&nbsp;85</td> <td bgcolor="#cccccc">&nbsp;ECMR&nbsp;Ⅲ, H-CAM, HUTCH-1, Hermes, Lu, Pgp-1, gp85&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Surface of most cell types&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Adhesion molecule mediating leukocyte attachment and homing to peripheral lymphoid organs and sites of inflammation&nbsp;</td>
</tr>
<tr>
<td><strong>&nbsp;CD44R</strong></td>
<td>&nbsp;85-250 in epithelial cells; 85-200 in lymphocytes</td> <td>&nbsp;CD44v, CD44v9; heterogenous group of CD44 variant isoforms designated by the variant exons that they&nbsp;include (v2-v10 in humans)&nbsp;</td> <td>&nbsp;Epithelial cells and monocytes (constitutively), activated leukocytes&nbsp;</td> <td>&nbsp;Possible role (particulary for CD44v6) in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation&nbsp;</td>
</tr>
<tr>
<td bgcolor="#cccccc"><strong>&nbsp;CD45</strong></td>
<td bgcolor="#cccccc">&nbsp;210, 220, 180, 200</td> <td bgcolor="#cccccc">&nbsp;Leukocyte common antigen (LCA), T200, EC 3.1.3.4; many dofferent isoforms with different molecular weights, e.g..<br /> B220, CD45R, CD45RA, CD45RB, CD45RC, CD45RO&nbsp;</td> <td bgcolor="#cccccc">&nbsp;All hematopoeitic cells; different isoforms characteristic of differentiated subsets of various hematopoeitic cells</td> <td bgcolor="#cccccc">&nbsp;Essential role in T-and B-cell antigen-receptor-mediated activation; possible role in receptor-mediated activation in other leukocytes&nbsp;</td>
</tr>
</tbody>
</table>

Navigation menu