<a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_ceramidePathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_ceramidePathway.gif</a>&nbsp;<br /><br /><table style="WIDTH: 693px; HEIGHT: 443px" cellspacing="1" cellpadding="1" width="693" summary="" border="1"> <tbody> <tr> <td>&nbsp;</td> <td>&nbsp;</td> </tr> <tr> <td> <p align="center">TRAF2</p> </td> <td> <p align="center">TRADD</p> </td> </tr> <tr> <td> <p align="center">TRAF2</p> </td> <td> <p align="center">NFkB</p> </td> </tr> <tr> <td> <p align="center">TRADD</p> </td> <td> <p align="center">TNF R1</p> </td> </tr> <tr> <td> <p align="center">TRADD</p> </td> <td> <p align="center">RIP</p> </td> </tr> <tr> <td> <p align="center">TRADD</p> </td> <td> <p align="center">TRAF2</p> </td> </tr> <tr> <td> <p align="center">TRADD</p> </td> <td> <p align="center">FADD</p> </td> </tr> <tr> <td> <p align="center">BAX</p> </td> <td> <p align="center">BAD</p> </td> </tr> <tr> <td> <p align="center">BAX</p> </td> <td> <p align="center">Mitochondrial Permeability</p> </td> </tr> <tr> <td> <p align="center">BAX</p> </td> <td> <p align="center">Ceramide</p> </td> </tr> <tr> <td> <p align="center">BAX</p> </td> <td> <p align="center">BCL-2</p> </td> </tr> <tr> <td> <p align="center">FADD</p> </td> <td> <p align="center">TRADD</p> </td> </tr> <tr> <td> <p align="center">FADD</p> </td> <td> <p align="center">A-SMase</p> </td> </tr> <tr> <td> <p align="center">FADD</p> </td> <td> <p align="center">Flice-like protease</p> </td> </tr> <tr> <td> <p align="center">BCL2</p> </td> <td> <p align="center">Ceramide</p> </td> </tr> <tr> <td> <p align="center">BCL2</p> </td> <td> <p align="center">BAX-BAD Complex</p> </td> </tr> <tr> <td> <p align="center">NFkB</p> </td> <td> <p align="center">ERK1-ERK2 Complex</p> </td> </tr> <tr> <td> <p align="center">NFkB</p> </td> <td> <p align="center">Flice-like protease</p> </td> </tr> <tr> <td> <p align="center">BAD</p> </td> <td> <p align="center">BAX</p> </td> </tr> <tr> <td> <p align="center">BAD</p> </td> <td> <p align="center">BCL-2</p> </td> </tr> <tr> <td> <p align="center">BAD</p> </td> <td> <p align="center">Mitochondrial permeability</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">&nbsp;</p> </td> </tr> </tbody></table><br />Transcription Factor<br />-NFkB