Chaperons modulate interferon Signaling Pathway
From Opengenome.net
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_tidPathway.gif
JAK2 |
IFN-rR |
JAK2 |
HSP70 |
JAK2 |
TID1 |
IFNGR1 |
JAK2 |
IFNGR1 |
TID1 |
IFNGR1 |
HSP70 |
IFNGR1 |
IFNr |
WT1 |
p53 |
WT1 |
RB |
HSPA4 |
TID1 |
IKBKB |
IKBa |
IKBKB |
TID1 |
NFkB |
NFkB Pathway |
p53 |
RB |
p53 |
WT1 |
p53 |
TID1 |
RB1 |
TID1 |
RB1 |
p53 |
RB1 |
WT1 |
TNFR |
TNF |
TNFR |
NFkB Pathway |
TNF |
TNFR |
TNF |
NFkB Pathway |
Transcription Factor
-WT1, p53, RB