Chaperons modulate interferon Signaling Pathway

From Opengenome.net

http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_tidPathway.gif 

   

JAK2

IFN-rR

JAK2

HSP70

JAK2

TID1

IFNGR1

JAK2

IFNGR1

TID1

IFNGR1

HSP70

IFNGR1

IFNr

WT1

p53

WT1

RB

HSPA4

TID1

IKBKB

IKBa

IKBKB

TID1

NFkB

NFkB Pathway

p53

RB

p53

WT1

p53

TID1

RB1

TID1

RB1

p53

RB1

WT1

TNFR

TNF

TNFR

NFkB Pathway

TNF

TNFR

TNF

NFkB Pathway



Transcription Factor
-WT1, p53, RB