CD166-180
From Opengenome.net
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
CD166 | 100-105 | BEN, DM-GRASP, KG-CAM, neurolin, SC-1, activated-leukocyte cell-adhesion molecule (ALCAM) | Activated T cells, activated monocytes, epithelium, neurons, fibroblasts | Adhesion molecule that binds to CD6 |
CD167 | α subunit 54, β subunit 63 | DDR1 (discoidin domain family member 1) | Mainly normal and transformed epithelial cells | Receptor tyrosine kinase activated by various types of collagen |
CD168 | 85-95 | RHAMM (receptor for hyaluronan-mediated motility) | Some fibroblast cell lines, lymphovytes, hematopoietic progenitor cells and malignant B lymphocytes | Expressed on a hyaluronan-binding receptor that participates in the hyaluronan-dependent motility of thymocytes, lymphocytes, hematopoeitic progenitor cells, and malignant B lymphocytes |
CD169 | 220 | SIGLEC-1 (sialic acid ctin-1); Sialoadhesion | Macrophages | Mediates cell-cell interactions by binding to sialylated ligands on neutrophils, monocytes, NK cells, B cells, and a subset of CD8+ T cells |
CD170 | 140 | SIGLEC-5 (sialic acid binding Ig-like lectin-1) | Relatively high levels on neutrophils | May be involved in sialic acid-dependent cell-cell interactions |
CD171 | 200-230 | L1 cell adhesion molecule | Low to intermediate expression on human lymphoid and myelomonocytic cells including CD4+ T cells, a subset of B cells, monocytes, monocyte-derived dendritic cells, many cells of the central and peripheral nervous system | Cell adhesion molecule that plays a role in the maintenance of pymph node architecture during an immune response |
CD173 | H2, blood group O antigen | Among hematopoietic cells, present on erythrocytes and CD34+ hematopoietic precursors | Glycoprotein-borne oligosaccharide | |
CD174 | Lewis Y blood group antigen | Among hematopoietic cells, present on erythrocytes and CD34+ hematopoietic precursors | Glycoprotein-borne oligosaccharide | |
CD177 | 58-64 | NB1 | Surfaces and secondary granules of neutrophils | Glycoprotein |
CD178 | Monomer of cell surface form 40; soluble forms 26-30 | Fas ligand, FasL | Constitutive or induced expression on many cell types including T cells, NK cells, microglial cells, neutrophils, nonhematopoietic cells such as retinal and corneal parenchymal cells | Not known |
CD179a | 16-18 | VpreB | Selectively expressed in pro-B and early pre-B cells | Associates with CD 179b to form surrogate light chain if the preB cell receptor |
CD179b | 22 | Lambda5 | Selectively expressed in pro-B and early pre-B cells | Associates with CD 179a to form surrogate light chain if the preB cell receptor |
CD180 | 95-105 | RP105, LY64 | Monocytes, dendritic cells, mantle zone B cells | Not known |