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Adhesion and Diapedesis of Lymphocytes

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<a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_lymPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_lymPathway.gif</a><br /><br />B cell과 T cell lymphocytes는 그들의 immune function의 부분인 cell의 다양한 부분과 서로 상호작용을 하고, 염증의 signals와 같은 조직의 특이한 상태에서 순환하고, 귀환한다.<br />Vascular endothelial cells 와 같은 다른 cell 종류와 lymphocytes의 상호작용은 VLA-4, LFA-a, CD44, CD31, L-selectin과 같은 분자가 필요하다.<br /><br />Pathway Interaction<br /><table style="WIDTH: 756px; HEIGHT: 258px" cellspacing="1" cellpadding="1" width="756" summary="" border="1"> <tbody> <tr> <td>&nbsp;</td> <td>&nbsp;</td> </tr> <tr> <td> <p align="center">CD34</p> </td> <td> <p align="center">L-Selectin</p> </td> </tr> <tr> <td> <p align="center">GLYCAM</p> </td> <td> <p align="center">L-Selectin</p> </td> </tr> <tr> <td> <p align="center">VCAM-1</p> </td> <td> <p align="center">CD29</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">CD49D</p> </td> </tr> <tr> <td> <p align="center">PECAM-1</p> </td> <td> <p align="center">Tissue</p> </td> </tr> <tr> <td> <p align="center">ICAM1<br />ICAM2</p> </td> <td> <p align="center">CD11a</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">CD18</p> </td> </tr> <tr> <td> <p align="center">IL-8</p> </td> <td> <p align="center">CD49D</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">CD29</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">CD18</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">CD11a</p> </td> </tr> </tbody></table>

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