Erk1/Erk2 Mapk Signaling Pathway

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PTPRR

ERK2

PTPRR

PP2A

SHC

GRB2

SHC

NGFR

SHC

SRC

MNK2

MNK1

MNK2

ERK1-ERK2 Complex

STAT3

ERK2-ERK1 Complex

SRC

GBr

SRC

SHC

RAF1

RAS

RAF1

MEK1-MEK2 Complex

ELK1

ERK1-ERK2 Complex

SOS1

GTP

SOS1

GRB2

MYC

MYC

MYC

ERK1-ERK2 Complex

NGF

NGFR

NGFR

NGF

NGFR

SHC

GRB2

SOS-1

GRB2

SHC

MNK1

MNK2

MNK1

ERK1-ERK2 Complex


TRANSCRIPTION FACTOR
=STAT3, ELK1