Cdc25 and chk1 Regulatory Pathway in Response to DNA damage

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http://cgap.nci.nih.gov/BIOCARTA/Pathways/H_cdc25Pathway.gif

   

CDC2

CDC25

CDC2

WEE1

CDC2

MYT1

CDC2

Mitotic cycle

CHEK1

ATM

CHEK1

CDC25

WEE1

CDC2

MYT

CDC2-Tyr15 phosphorylation

MYT

CDC2-Thr14 phosphorylation

ATM

Damage DNA

ATM

CHK1
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