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Insight: Stem Cells

VolVolVolVol. 441, NoNoNoNo. 7097 pppppppp1059-1102

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In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease.

This Nature Insight is accompanied by a special stem cells podcast, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field.

Readers are invited to join an web forum to exchange views and opinions raised by the Insight articles. There is also a podcast forum for issues discussed in the stem cells podcast.

In this supplement

• Editorial
• Glossary
• Reviews
• Progress
• Podcast
• Web forum
• Insight Sponsors: Invitrogen

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Editorial

Stem-cell Biology Free access

Natalie DeWitt

doidoidoi:10.1038/4411059a

Abstract |Full Text | PDFPDFPDF (164KBKBKB)

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Glossary

A glossary for stem-cell biology Free access

Austin Smith

doidoidoi:10.1038/nature04954

Abstract |Full Text | PDFPDFPDF (68KBKBKB)

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Reviews

Nuclear reprogramming and pluripotency Free access

Konrad Hochedlinger and Rudolf Jaenisch

doidoidoi:10.1038/nature04955

Abstract | Full Text | PDFPDFPDF (644KBKBKB)

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Asymmetric and symmetric stem-cell divisions in development and cancer Free access

Sean J. Morrison and Judith Kimble

doidoidoi:10.1038/nature04956

Abstract | Full Text | PDFPDFPDF (473KBKBKB)

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The stem-cell niche as an entity of action Free access

David T. Scadden

doidoidoi:10.1038/nature04957

Abstract | Full Text | PDFPDFPDF (323 KBKBKB)

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Stem cells, ageing and the quest for immortality Free access

Thomas A. Rando

doidoidoi:10.1038/nature04958

Abstract | Full Text | PDFPDFPDF (641 KBKBKB)

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Generation of neuronal variability and complexity Free access

Alysson R. Muotri and Fred H. Gage

doidoidoi:10.1038/nature04959

Abstract | Full Text | PDFPDFPDF (756 KBKBKB)

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Progress

Stem cells for the treatment of neurological disorders Free access

Olle Lindvall and Zaal Kokaia

doidoidoi:10.1038/nature04960

Abstract | Full Text | PDFPDFPDF (402KBKBKB)

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Potential of stem-cell-based therapies for heart disease Free access

Deepak Srivastava and Kathryn N. Ivey

doidoidoi:10.1038/nature04961

Abstract | Full Text | PDFPDFPDF (345 KBKBKB)

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Stem-cell therapies for blood diseases Free access

Claudio Bordignon

doidoidoi:10.1038/nature04962

Abstract | Full Text | PDFPDFPDF (323 KBKBKB)

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