Bioinformatics centers

Bioinformatics research and service centers around the world.

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Major Genomic Information Repositories

• NCBI The National Center for Biotechnology Information - Bethesda MD, USA
• EBI The European Bioinformatics Institute - Hinxton, UK
• GDB US The Genome Database - Baltimore MD, USA
• GDB UK The Genome Database, European Mirror Site - Hinxton, UK (faster)
• CHLC Cooperative Human Linkage Center - Iowa City IA, USA
• TIGR The Institute for Genomic Research - Gaithersburg MD, USA
• IMAGE Consortium - Livermore CA, USA
• CIB The Center for Information Biology - Mishima, Japan 

Medical Genetics

• OMIM Online Mendelian Inheritance in Man - Bethesda MD, USA
• HGMD Human Gene Mutation Database - Cardiff, UK
• Genetic Linkage Analysis Web Resource - New York NY, USA
• CGAP NCI Cancer Genome Anatomy Project - Bethesda MD, USA
• LBL Resource for Molecular Cytogenetics - Berkeley CA, USA
• The Dysmorphic Mouse-Human Homology Database - Hinxton, UK

Developmental Biology

• Society for Developmental Biology - West Lafayette IN, USA
• Zygote Web Site - Swarthmore PA, USA
• Human Embryology Web Site - Cincinatti OH, USA
• UCSF Visible Embryo Project - San Francisco CA, USA
• FlyView - Muenster, Germany
• The Zebrafish Server European Mirror Site - Strasbourg, France
• Mouse Atlas and Gene Expression Database - Edinburgh, UK
• Organogenesis Database - Edinburgh, UK
• Human Atlas Database - Edinburgh, UK
• Tooth Development Web Site - Helsinki, Finland

Anatomy Resources

• Veterinary Anatomy and Radiology - Athens GA, USA
• Human Pathology Atlas - Urbana IL, USA
• The Whole Brain Atlas - Cambridge MA, USA
• Atlas of the Primate Brain - Seattle WA, USA
• The Visible Human Project - Bethesda MD, USA

Cell Lines and Clones

• ATCC American Type Culture Collection - Rockville MD, USA
• European Collection of Animal Cell Cultures - Baltimore MD, USA
• Fungal Genetics Stock Center - Daresbury, UK
• Human Genetic Mutant Cell Repository - Camden NJ, USA
• Genline - Seattle WA, USA
• IMAGE Consortium - Livermore CA, USA

Genome Mapping

• RZPD German Human Genome Project Resource Centre - Berlin, Germany
• LDB The Genetic Location Database - Southampton, UK
• GeneCards: human genes, proteins and diseases - Rehovot, Israel
• University of Washington Cytogenetics - Seattle WA, USA
• Resource for Molecular Cytogenetics - Berkeley CA, USA

Genome Centres - USA

• NIH National Human Genome Research Institute - Bethesda MD
• Joint Genome Institute - Los Alamos - Lawrence Berkeley - Lawrence Livermore Cosortium
• National Center for Genome Resources - Santa Fe NM
• Baylor College of Medicine Genome Center - Houston TX
• TIGR The Institute for Genomic Research - Gaithersburg MD
• Stanford Human Genome Center - Palo Alto CA
• Stanford DNA Sequence and Technology Center - Palo Alto CA
• UC Berkeley Drosophila Genome Center - Berkeley CA
• University of Washington Genome Center - Seattle WA
• University of Wisconsin E. coli Genome Center - Madison WI
• Washington University Genome Sequencing Center - St Louis MO
• Whitehead Institute Genome Center - Cambridge MA
• CalTech Genome Research Laboratory - Pasadena CA

Genome Centres - International

• CEPH - Paris, France
• Genethon - Paris, France
• HGMP MRC Human Genome Mapping Resource Centre - Hinxton, UK
• The Sanger Centre - Cambridge, UK
• Roslin Institute - Edinburgh, UK
• The Weizmann Institute of Science Genome Center - Rehovot, Israel
• GenomeNet - Kyoto, Japan
• ANGIS Australian National Genomic Information Service - Sydney, Australia
• SANBI South African National Bioinformatics Institute - Cape Town, South Africa

Human Chromosome-Specific Web Sites

• Chromosome 1 Rockefeller University - New York NY, USA
• Chromosome 3 University of Texas - San Antonio TX, USA
• Chromosome 5 University of California at Irvine - Irvine CA, USA
• Chromosome 6 Sanger Centre - Hinxton, UK
• Chromosome 7 Hospital for Sick Children - Toronto, Canada
• Chromosome 8 University of Texas - San Antonio TX, USA
• Chromosome 9 UCL - London, UK
• Chromosome 10 Genome Therapeutics Corp. - Waltham MA, USA
• Chromosome 11 University of Texas Southwestern Medical Center - Dallas TX, USA
• Chromosome 12 Yale University - New Haven CT, USA
• Chromosome 13 Columbia University - New York NY, USA
• Chromosome 15 University of British Columbia - Vancouver, Canada
• Chromosome 16 LANL - Los Alamos NM, USA
• Chromosome 17 Weizmann Institute of Science - Rehovot, Israel
• Chromosome 18 Children's Hospital - Boston MA, USA
• Chromosome 19 LLNL - Livermore CA, USA
• Chromosome 22 University of Pennsylvania - Philadelphia PA, USA
• Chromosome 22 Sanger Centre - Hinxton, UK
• Chromosome X Baylor College of Medicine - Houston TX, USA
• Mitochondrial Chromosome Emory University - Atlanta GA, USA

Genome Projects - Model Organisms

• WIT Interactive Metabolic Reconstruction Server - Argonne IL, USA
• MICADO Bacillus subtilis Database - Jouy-en-Josas, France Bacterial Genomes Server - Cambridge, UK
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• Stanford SacchDB Saccharomyces Database - Palo Alto CA, USA
• NIH Campus Yeast Interest Group - Bethesda MD, USA
• The Schizosaccharomyces pombe Genome Project - Hinxton, UK
• Fungal Genome Resource - Athens GA, USA
• Caenorhabditis elegans Server - Dallas TX, USA
• Caenorhabditis elegans Server - Hinxton, UK
• FlyBase (Drosophila) Server - Hinxton, UK
• The Xenopus Molecular Marker Resource - Houston TX, USA
• The Fugu Genome Project - Hinxton, UK
• Stanford AtDB Arabidopsis Database - Palo Alto CA, USA
• Jackson Laboratory Mouse Genome Database - Bar Harbor ME, USA
• The WashU-HHMI Mouse EST Project - St Louis MO, USA
• The European Collaborative Interspecific Mouse Backcross - Hinxton, UK

Sequence Analysis

• ExPaSy Web Site - Geneva, Switzerland
• PROSITE Dictionary of Protein Sites and Patterns - Geneva, Switzerland
• SWISS-PROT Protein Sequence Database - Geneva, Switzerland
• DbBrowser Bioinformatics Web Server - University College London, UK
• PRINTS Protein Motif Fingerprint Database - University College London, UK
• OWL Composite Protein Sequence Database - University College London, UK
• ALIGN Sequence Alignment Compendium - University College London, UK
• ProDom Protein Domain Database - Toulouse, France
• Pfam Database of Protein Domain Families - Hinxton, UK
• Weizmann Institute Genome and Bioinformatics - Rehovot, Israel
• TRANSFAC Transcription Factor Database - Braunschweig, Germany
• Baylor C ollege of Medicine Search Launcher - Houston TX, USA
• GRAIL Coding Region Prediction Server - Oak Ridge TN, USA
• GENSCAN Gene Structure Prediction Server - Palo Alto CA, USA
• Lawrence Berkeley Lab Promoter Prediction Server - Berkeley CA, USA
• Lawrence Berkeley Lab Splice Site Prediction Server - Berkeley CA, USA
• Lawrence Berkeley Lab Gene Finder - Berkeley CA, USA
• TESS Transcription Element Search Software - Philadelphia PA, USA
• BLOCKS Server - Seattle WA, USA
• The RNA Page by Mike Zuker - St Louis MO, USA
• The p53 Web Resource - Paris, France
• Joe Felsenstein Lab Phylogeny Server - Seattle WA, USA

Structural Biology

• PDB US Protein Data Bank - Brookhaven NY, USA
• PDB UK Protein Data Bank, European Mirror Site - Hinxton, UK (faster)
• ICRF Biomolecular Modelling Laboratory - 44 LIF
• SCOP Structural Classification of Proteins - Cambridge, UK
• CATH Protein Structure Classification - London, UK
• NIH Molecules R Us - Bethesda MD, USA
• Molecular Design Institute - San Francisco CA, USA
• Protein Kinase Resource - San Diego CA, USA
• National Center for Microscopy and Imaging Research - San Diego CA, USA

Proteome Related

• Biobase 2-D Gel Database - Aarhus, Denmark
• PROLYSIS Protease Web Server - Toulouse, France
• EMBL Protein and Peptide Group - Heidelberg, Germany
• MOWSE Peptide Mass Database Server - Daresbury, UK
• PDD NIH Protein-Disease Database - Bethesda MD, USA
• The Cytoskeletal Protein Interactions Database - New Haven CT, USA

Major Research Centres Worldwide

• MRC Laboratory of Molecular Biology - Cambridge, UK
• Imperial College of Science, Technology and Medicine - London, UK
• EMBL - Heidelberg, Germany
• Max-Planck-Gesellschaft - Munich, Germany (with links to all Max-Planck Institutes)
• DKFZ German Cancer Research Centre - Heidelberg, Germany
• Biozentrum - Basel, Switzerland
• Basel Institute for Immunology - Basel, Switzerland
• Friedrich-Miescher-Institut - Basel, Switzerland
• Institut Pasteur - Paris, France
• Ecole Normale Superieure - Paris, France
• Karolinska Institutet - Stockholm, Sweden
• International Center for Genetic Engineering and Biotechnology - Trieste, Italy
• Weizmann Institute of Science - Rehovot, Israel
• National Institutes of Health - Bethesda MD, USA
• Centers for Disease Control and Prevention - Atlanta GA, USA
• Cold Spring Harbor Laboratory - Cold Spring Harbor NY, USA
• Salk Institute - San Diego CA, USA
• Scripps Institute - San Diego CA, USA
• Mayo Clinic - Rochester MN, USA
• Argone National Laboratory - Argonne IL, USA
• Brookhaven National Laboratory - Brookhaven NY, USA
• Lawrence Berkeley National Laboratory - Berkeley CA, USA
• Lawrence Livermore National Laboratory - Livermore CA, USA
• Los Alamos National Laboratory - Los Alamos NM, USA
• Oak Ridge National Laboratory - Oak Ridge TN, USA
• Sandia National Laboratories - Albuquerque NM and Livermore CA, USA

Other Information Resources

• WHO World Health Organization - Geneva, Switzerland
• NCI CancerNet European Mirror Site - Bonn, Germany
• The Wellcome Trust - London, UK
• CORDIS Community Research and Development Information Service (European Commission) - Luxembourg
• US Dept of Energy Biology Information Center
• US Dept of Energy Human GenomeNewsletter
• HUGO The Human Genome Organisation - Baltimore MD, USA
• Environmental Mutagen Society - Oak Ridge TN, USA
• Washington Fax - Biotechnology Policy Information
• Howard Hughes Medical Institute - Chevy Chase MD, USA
• Access Excellence - from Genentech, Inc.
• The Scientist - University of Pennsylvania
• Doctor's Guide to the Internet
• Intellectual Property Law

Frequently Asked Questions

• How much of the human genome has been sequenced?
• Mapped human genes by chromosome from GDB - Hinxton, UK
• Human inherited disease genes identified by positional cloning from NCBI - Bethesda MD, USA
• The MAGPIE list of genome projects - Argonne IL, USA
• DOGS Database of Genome Sizes - Copenhagen, Denmark

  Pharma and Biotech Companies - Europe

  • Astra - Sweden
  • Bayer - Germany
  • Boehringer Mannheim - Germany
  • Evotec - Germany
  • Glaxo Wellcome - UK
  • Hoechst - Germany
  • Lion bioscience - Germany
  • Novartis - Switzerland
  • Qiagen - Germany
  • Rhone-Poulenc - France
  • Roche - Switzerland
  • Zeneca - UK
  • UK Business Park

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• Pharma and Biotech Companies - USA

  • Abbott
  • Affymetrix
  • AGCT
  • Amgen
  • Ariad
  • Bristol-Myers Squibb
  • Caliper Technologies
  • Cell Genesys
  • Chiron
  • Curagen
  • Eli Lilly
  • Genentech
  • Genetics Institute
  • Incyte
  • Invitrogen
  • Merck
  • Myriad
  • New England Biolabs
  • Novagen
  • Pfizer
  • Promega
  • Rhone-Poulenc Rorer
  • Searle
  • Sequana
  • SmithKline Beecham
  • Synteni
  • Vertex