[http://en.wikipedia.org/wiki/Microbiologist <h2p><strong>Microbiologist - Wikipedia, the free encyclopediaBioinformatics</h2strong> and <strong>]computational biology<br /strong>Keywords: [[Microbiologist]]involve the use of techniques including applied mathematics, informatics, [[Bachelor of Science]]statistics, computer science, [[Bacteria]]artificial intelligence, [[Biologist]]chemistry, [[Biology]]and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, [[Biotechnology]]gene finding, [[Environmental science]]genome assembly, [[Epidemiology]]protein structure alignment, [[Food industry]]protein structure prediction, [[Foodborne illness]]prediction of gene expression and protein-protein interactions, [[Fungi]]and the modeling of evolution.<br /p>[http:<p> <//siteanalytics.compete.com/wikipedia.org p><font sizeh2><span class="1mw-headline">Introduction<strong/span>Visitors</strongh2><p>The terms <em>bioinformatics</fontem> and <em>] | [http:computational biology<//wwwem> are often used interchangeably.alexa.comHowever <em>bioinformatics</data/details/main?url=wikipediaem> more properly refers to the creation and advancement of algorithms, computational and statistical techniques, and theory to solve formal and practical problems inspired from the management and analysis of biological data.org <font size="1"em><strong>AlexaComputational biology,</strongem></font>] | [http://whoison the other hand, refers to hypothesis-driven investigation of a specific biological problem using computers, carried out with experimental or simulated data, with the primary goal of discovery and the advancement of biological knowledge.domaintoolsPut more simply, bioinformatics is concerned with the information while computational biology is concerned with the hypotheses.com/wikipedia.org <font size="1"A similar distinction is made by National Institutes of Health in their working definitions of Bioinformatics and Computational Biology, where it is further emphasized that there is a tight coupling of developments and knowledge between the more hypothesis-driven research in computational biology and technique-driven research in bioinformatics.</p><strongp>Domain A common thread in projects in bioinformatics and computational biology is the use of mathematical tools to extract useful informationfrom data produced by high-throughput biological techniques such as genome sequencing. A representative problem in bioinformatics is the assembly of high-quality genome sequences from fragmentary "shotgun" DNA sequencing. Other common problems include the study of gene regulation using data from microarrays or mass spectrometry.</strongp><p> </fontp>] | [http://www.iwebtool.com/tool/tools/rank/rank.php?domain=wikipedia.org <font sizeh2><span class="1mw-headline">Major research areas<strong/span>Iwebtool</strongh2></fontp>] <br /p><a hrefh3><span class="http:mw-headline">Sequence analysis</span></siteanalytics.compete.com/wikipedia.org?metric=uv"h3><img alt="" src="http://homep>Since the Phage Φ-X174 was sequenced in 1977, the DNA sequences of hundreds of organisms have been decoded and stored in databases.competeThe information is analyzed to determine genes that encode polypeptides, as well as regulatory sequences.comA comparison of genes within a species or between different species can show similarities between protein functions, or relations between species (the use of molecular systematics to construct phylogenetic trees).edgesuiteWith the growing amount of data, it long ago became impractical to analyze DNA sequences manually.net/wikipediaToday, computer programs are used to search the genome of thousands of organisms, containing billions of nucleotides. These programs would compensate for mutations (exchanged, deleted or inserted bases) in the DNA sequence, in order to identify sequences that are related, but not identical.org_uv_310A variant of this sequence alignment is used in the sequencing process itself.png" /></a>The so-called shotgun sequencing technique (which was used, for example, by The Institute for Genomic Research to sequence the first bacterial genome, <br /em>Haemophilus influenzae<br /em> [http://en.wikipedia.org/wiki/Microbiology <h2>Microbiology - Wikipedia) does not give a sequential list of nucleotides, but instead the free encyclopediasequences of thousands of small DNA fragments (each about 600-800 nucleotides long). The ends of these fragments overlap and, when aligned in the right way, make up the complete genome. Shotgun sequencing yields sequence data quickly, but the task of assembling the fragments can be quite complicated for larger genomes. In the case of the Human Genome Project, it took several months of CPU time (on a circa-2000 vintage DEC Alpha computer) to assemble the fragments. Shotgun sequencing is the method of choice for virtually all genomes sequenced today, and genome assembly algorithms are a critical area of bioinformatics research.</h2p>]<br /p>Keywords: [[Microbiology]]Another aspect of bioinformatics in sequence analysis is the automatic search for genes and regulatory sequences within a genome. Not all of the nucleotides within a genome are genes. Within the genome of higher organisms, [[Biologylarge parts of the DNA do not serve any obvious purpose. This so-footer]]called junk DNA may, [[Industrial microbiology]]however, [[1822]]contain unrecognized functional elements. Bioinformatics helps to bridge the gap between genome and proteome projects--for example, [[1828]], [[1843]], [[1851]], [[1856]], [[1895]], [[1898]], [[1910]]in the use of DNA sequences for protein identification.<br /p>[http<p><em>See also:</em> sequence analysis, sequence profiling tool, sequence motif.</siteanalytics.compete.comp><p> </wikipedia.org p><h4><font sizespan class="1mw-headline">Genome annotation<strong/span>Visitors</strongh4></font>] | [http://www.alexa.com/data/details/main?url=wikipedia.org <font size="1"p>In the context of genomics, <strong>Alexaannotation</strong></font>] | [http://whoisis the process of marking the genes and other biological features in a DNA sequence.domaintoolsThe first genome annotation software system was designed in 1995 by Dr.com/wikipediaOwen White, who was part of the team that sequenced and analyzed the first genome of a free-living organism to be decoded, the bacterium Haemophilus influenzae. Dr.org <font size=White built a software system to find the genes (places in the DNA sequence that encode a protein), the transfer RNA, and other features, and to make initial assignments of function to those genes. Most current genome annotation systems work similarly, but the programs available for analysis of genomic DNA are constantly changing and improving.</p><p> </p><h3><span class="1mw-headline">Computational evolutionary biology<strong/span>Domain information</strongh3></fontp>] | [httpEvolutionary biology is the study of the origin and descent of species, as well as their change over time. Informatics has assisted evolutionary biologists in several key ways; it has enabled researchers to:</p><ul> <li>trace the evolution of a large number of organisms by measuring changes in their DNA, rather than through physical taxonomy or physiological observations alone, </www.iwebtool.com/tool/tools/rankli> <li>more recently, compare entire genomes, which permits the study of more complex evolutionary events, such as gene duplication, lateral gene transfer, and the prediction of bacterial speciation factors, </rank.php?domain=wikipedia.org <font size="1"li> <strongli>Iwebtoolbuild complex computational models of populations to predict the outcome of the system over time </strongli> <li>track and share information on an increasingly large number of species and organisms </fontli>] <br /ul><a href="http://siteanalyticsp>Future work endeavours to reconstruct the now more complex tree of life.compete.com</wikipedia.org?metric=uv"p><img alt="" src="http://homep>The area of research within computer science that uses genetic algorithms is sometimes confused with computational evolutionary biology, but the two areas are unrelated.compete.com.edgesuite.net</wikipedia.org_uv_310.png" p><p> </p></ah3><span class="mw-headline">Measuring biodiversity<br /span><br /h3> [http://www.whatreallyhappened.com/deadbiologists.html <h2>The mysterious deaths <p>Biodiversity of an ecosystem might be defined as the total genomic complement of top microbiologists since 9/11</h2>]<br />Keywords: [[what really happened]]a particular environment, [[ whatreallyhappened]]from all of the species present, whether it is a biofilm in an abandoned mine, a drop of sea water, a scoop of soil, [[ dead microbiologists]]or the entire biosphere of the planet Earth. Databases are used to collect the species names, [[ cover-up]]descriptions, [[ deception]]distributions, [[ government lies]]genetic information, [[ mainstream media lies]]status and size of populations, habitat needs, and how each organism interacts with other species. Specialized software programs are used to find, visualize, and analyze the information, and most importantly, communicate it to other people. Computer simulations model such things as population dynamics, or calculate the cumulative genetic health of a breeding pool (in agriculture) or endangered population (in conservation). One very exciting potential of this field is that entire DNA sequences, or genomes of endangered species can be preserved, allowing the results of Nature's genetic experiment to be remembered <br /em>[http:in silico<//siteanalyticsem>, and possibly reused in the future, even if that species is eventually lost.compete.com</whatreallyhappened.com p><font size="1"p><strongem>VisitorsImportant projects:</strongem>Species 2000 project; uBio Project.</fontp>] | [http:<p> <//www.alexa.com/data/details/main?url=whatreallyhappened.com p><h3><font sizespan class="1mw-headline"><strong>AlexaAnalysis of gene expression</strongspan></fonth3>] | [http://whois.domaintools.com/whatreallyhappened.com <font size="1"p><strong>Domain information</strong></font>] | [http://wwwThe expression of many genes can be determined by measuring mRNA levels with multiple techniques including microarrays, expressed cDNA sequence tag (EST) sequencing, serial analysis of gene expression (SAGE) tag sequencing, massively parallel signature sequencing (MPSS), or various applications of multiplexed in-situ hybridization.iwebtool.com/toolAll of these techniques are extremely noise-prone and/or subject to bias in the biological measurement, and a major research area in computational biology involves developing statistical tools/rank/rankto separate signal from noise in high-throughput gene expression studies.php?domain=whatreallyhappenedSuch studies are often used to determine the genes implicated in a disorder: one might compare microarray data from cancerous epithelial cells to data from non-cancerous cells to determine the transcripts that are up-regulated and down-regulated in a particular population of cancer cells.com <font size="1"/p><strongp>Iwebtool </strongp><h3><span class="mw-headline">Analysis of regulation</fontspan>] <br /h3><a href="http://siteanalyticsp>Regulation is the complex orchestration of events starting with an extra-cellular signal and ultimately leading to an increase or decrease in the activity of one or more protein molecules.competeBioinformatics techniques have been applied to explore various steps in this process.com/whatreallyhappened.com?metric=uv"><img alt="" src="httpFor example, promoter analysis involves the elucidation and study of sequence motifs in the genomic region surrounding the coding region of a gene. These motifs influence the extent to which that region is transcribed into mRNA. Expression data can be used to infer gene regulation://homeone might compare microarray data from a wide variety of states of an organism to form hypotheses about the genes involved in each state.competeIn a single-cell organism, one might compare stages of the cell cycle, along with various stress conditions (heat shock, starvation, etc.com).edgesuiteOne can then apply clustering algorithms to that expression data to determine which genes are co-expressed.net/whatreallyhappenedFor example, the upstream regions (promoters) of co-expressed genes can be searched for over-represented regulatory elements.com_uv_310.png" /></ap><br /p> <br /p> [http://www.medicalnewstoday.com/articles/83518.php <h2h3>Microbiologists Discover Lazy Cheating Bacteria</h2span class="mw-headline">Analysis of protein expression</span>]<br /h3>Baseball had its steroids <p>Protein microarrays and Black Soxhigh throughput (HT) mass spectrometry (MS) can provide a snapshot of the proteins present in a biological sample. Politics lived through Watergate. Wall Street has been riddled Bioinformatics is very much involved in making sense of protein microarray and HT MS data; the former approach faces similar problems as with insider trading scandals. And before we cast microarrays targeted at mRNA, the latter involves the problem of matching large amounts of mass data against predicted masses from protein sequence databases, and the first stonecomplicated statistical analysis of samples where multiple, who among us has never trbut incomplete peptides from each protein are detected.<br /p>Keywords: [[Infectious Diseases <p> </p><h3><span class="mw-headline">Analysis of mutations in cancer</ Bacteria span></ Viruses news]]h3><p>Massive sequencing efforts are currently underway to identify point mutations in a variety of genes in cancer. The sheer volume of data produced requires automated systems to read sequence data, [[ medical news]]and to compare the sequencing results to the known sequence of the human genome, [[ health news]]including known germline polymorphisms.</p><p>Oligonucleotide microarrays, [[ medical headlines]]including comparative genomic hybridization and single nucleotide polymorphism arrays, [[ healthcare news]], [[ health articles]], [[ medicine articles]], [[ welfare]], [[ living]]able to probe simultaneously up to several hundred thousand sites throughout the genome are being used to identify chromosomal gains and losses in cancer. Hidden Markov model and change-point analysis methods are being developed to infer real copy number changes from often noisy data. Further informatics approaches are being developed to understand the implications of lesions found to be recurrent across many tumors.<br /p>[http://siteanalytics<p>Some modern tools (e.competeg.com/medicalnewstodayQuantum 3.com <font size="1") provide tool for changing the protein sequence at specific sites through alterations to its amino acids and predict changes in the bioactivity after mutations.</p><strongp>Visitors </strongp></fonth3>] | [http://www.alexa.com/data/details/main?url=medicalnewstoday.com <font sizespan class="1mw-headline">Prediction of protein structure<strong/span>Alexa</strongh3></fontp>] | [http://whoisProtein structure prediction is another important application of bioinformatics.domaintools.com/medicalnewstoday.com The amino acid sequence of a protein, the so-called <font size="1"em><strong>Domain informationprimary structure</strongem></font>] | [http://www, can be easily determined from the sequence on the gene that codes for it.iwebtoolIn the vast majority of cases, this primary structure uniquely determines a structure in its native environment.com/tool/tools/rank/rank(Of course, there are exceptions, such as the bovine spongiform encephalopathy - aka Mad Cow Disease - prion.php?domain=medicalnewstoday) Knowledge of this structure is vital in understanding the function of the protein.com For lack of better terms, structural information is usually classified as one of <font size="1"em>secondary<strong/em>Iwebtool, </strongem>tertiary</fontem>] and <br /em>quaternary<a href="http://siteanalyticsem> structure.competeA viable general solution to such predictions remains an open problem.com/medicalnewstodayAs of now, most efforts have been directed towards heuristics that work most of the time.com?metric=uv"</p><img alt="" src="httpp>One of the key ideas in bioinformatics is the notion of homology. In the genomic branch of bioinformatics, homology is used to predict the function of a gene:if the sequence of gene <em>A<//home.compete.comem>, whose function is known, is homologous to the sequence of gene <em>B,</em> whose function is unknown, one could infer that B may share A's function.edgesuiteIn the structural branch of bioinformatics, homology is used to determine which parts of a protein are important in structure formation and interaction with other proteins.net/medicalnewstodayIn a technique called homology modeling, this information is used to predict the structure of a protein once the structure of a homologous protein is known.com_uv_310This currently remains the only way to predict protein structures reliably.png" </p></ap><br One example of this is the similar protein homology between hemoglobin in humans and the hemoglobin in legumes (leghemoglobin). Both serve the same purpose of transporting oxygen in the organism. Though both of these proteins have completely different amino acid sequences, their protein structures are virtually identical, which reflects their near identical purposes.</p><p>Other techniques for predicting protein structure include protein threading and <em>de novo</em>(from scratch) physics-based modeling.<br /p> [http://www<p>See also structural motif and structural domain.wisegeek.com</what-is-a-microbiologist.htm p><h2p>What is a Microbiologist? </h2p><h3><span class="mw-headline">]Comparative genomics<br /span>Brief and Straightforward Guide: What is a Microbiologist?<br /h3>Keywords: [[scientist]]<p>The core of comparative genome analysis is the establishment of the correspondence between genes (orthology analysis) or other genomic features in different organisms. It is these intergenomic maps that make it possible to trace the evolutionary processes responsible for the divergence of two genomes. A multitude of evolutionary events acting at various organizational levels shape genome evolution. At the lowest level, point mutations affect individual nucleotides. At a higher level, large chromosomal segments undergo duplication, [[ study]]lateral transfer, [[ microscope]]inversion, [[ life]]transposition, [[ cells]]deletion and insertion. Ultimately, whole genomes are involved in processes of hybridization, polyploidization and endosymbiosis, often leading to rapid speciation. The complexity of genome evolution poses many exciting challenges to developers of mathematical models and algorithms, who have recourse to a spectra of algorithmic, statistical and mathematical techniques, ranging from exact, [[ academic]]heuristics, [[ health]]fixed parameter and approximation algorithms for problems based on parsimony models to Markov Chain Monte Carlo algorithms for Bayesian analysis of problems based on probabilistic models.<br /p>[http:<p>Many of these studies are based on the homology detection and protein families computation.</p><p>See also comparative genomics, bayesian network and protein family.</siteanalytics.compete.comp><p> </wisegeek.com p><h3><font sizespan class="1mw-headline">Modeling biological systems<strong/span>Visitors</strongh3></fontp>] | [http://wwwSystems biology involves the use of computer simulations of cellular subsystems (such as the networks of metabolites and enzymes which comprise metabolism, signal transduction pathways and gene regulatory networks) to both analyze and visualize the complex connections of these cellular processes.alexaArtificial life or virtual evolution attempts to understand evolutionary processes via the computer simulation of simple (artificial) life forms.com</datap><p> </details/main?url=wisegeek.com <font sizep><h3><span class="1mw-headline">High-throughput image analysis<strong/span>Alexa</strongh3></fontp>] | [http://whoisComputational technologies are used to accelerate or fully automate the processing, quantification and analysis of large amounts of high-information-content biomedical imagery.domaintoolsModern image analysis systems augment an observer's ability to make measurements from a large or complex set of images, by improving accuracy, objectivity, or speed.com/wisegeekA fully developed analysis system may completely replace the observer.com Although these systems are not unique to biomedical imagery, biomedical imaging is becoming more important for both diagnostics and research. Some examples are:</p><font size="1"ul> <strongli>Domain informationhigh-throughput and high-fidelity quantification and sub-cellular localization (high-content screening, cytohistopathology) </strongli> <li>morphometrics </fontli>] | [http: <li>clinical image analysis and visualization <//www.iwebtool.com/tool/tools/rank/rank.php?domain=wisegeek.com <font size="1"li> <strongli>Iwebtooldetermining the real-time air-flow patterns in breathing lungs of living animals </strongli> </fontli>] quantifying occlusion size in real-time imagery from the development of and recovery during arterial injury <br /li> <li>making behavioral observations from extended video recordings of laboratory animals <a href="http:/li> <li>infrared measurements for metabolic activity determination </siteanalytics.compete.comli></ul><p> </wisegeek.com?metric=uv"p><img alth2><span class="mw-headline" src="http://home.compete.com.edgesuite.net/wisegeek.com_uv_310.png" />Software tools</aspan><br /><br /h2> [http://www.acvm.us/ <h2p>acvm.us</h2>]<br />Keywords: [[ACVM]]First generation bioinformatics tools consisted of applications, [[ American]]usually with a text-based interface, [[ College]]which performed a specific task well. The computational biology tool best-known among biologists is probably BLAST, [[ Veterinary]]an algorithm for searching large databases of protein or DNA sequences. The NCBI provides a popular web-based implementation that searches their massive sequence databases. Also fairly early on, [[ Microbiology]]due to the amassing of sequence and annotation data, [[ Immunology]], [[ Virology]], [[ General]]keyword search engines which were able to resolve gene and protein synonyms were important. Computer scripting languages such as Perl (thanks to its regular expressions handling facilities) and Python are often used to interface with biological databases and parse output from bioinformatics programs written in languages such as C or C++. Communities of bioinformatics programmers have set up free open source bioinformatics projects to develop and distribute the tools and modules they produce.</p><p>As the data sources expanded and diversified, [[ Bacteriology]]both in content and geography, [[ Diplomate]]bioinformatic meta search engines, [[ Certification]]such as Sequence profiling tools, [[ Application]], [[ Board]], [[ Governors]], [[ Veterinarian]], [[ Microbial]]emerged to help find relevant information from several databases. These meta search engines might index data from a local server or even from a panel of third party services.<br /p>[http://siteanalytics.compete.com/acvm.us <font size="1"p><strong>Visitors</strong></font>] | [http://www.alexa.com/More recently, SOAP-based interfaces have been developed for a wide variety of bioinformatics applications allowing an application running on one computer in one part of the world to use algorithms, data/details/main?url=acvmand computing resources on servers in other parts of the world. A large availability of these SOAP-based bioinformatics web services, along with the open source bioinformatics collections, lead to the next generation of bioinformatics tools: the integrated bioinformatics platform. These tools range from a collection of standalone tools with a common data format under a single, slick standalone or web-based interface, to integrative and extensible bioinformatics workflow development environments.us <font size="1"/p><strongp>Alexa </strongp></fonth2>] | [http:<span class="mw-headline">See also</span></whois.domaintools.com/acvm.us h2><h3><font sizespan class="1mw-headline">Related topics<strong/span>Domain information</strongh3></fontp>] | [http://www.iwebtool.com/tool/tools/rank/rank.php?domain=acvm.us <font sizetable> <tbody> <tr> <td valign="1top"> <strongul>Iwebtool </strongli>Biocybernetics </fontli>] <li>Bioinformatics companies <br /li> <li>Biologically-inspired computing <a href="http:/li> <li>Biomedical informatics </siteanalytics.compete.comli> <li>Computational biology </acvm.us?metric=uv"li> <li>Computational biomodeling <img alt="" src="http:/li> <li>Computational genomics </home.compete.com.edgesuite.net/acvm.us_uv_310.png" li> <li>Dot plot (bioinformatics) </li> </aul> <br /td> <br /td valign="top"> <ul>[http: <li>Metabolic network modelling </li> <li>Molecular modelling </www.sciencedaily.comli> <li>Morphometrics </releasesli> <li>Natural computation </2004/09/040922074503.htm li> <h2li>USF Microbiologists Can Detect Smallpox And Anthrax ASAPPharmaceutical company </h2li> <li>]Protein-protein interaction prediction <br /li>Keywords: [[Viruses]], [[ Infectious Diseases]], [[ Diseases and Conditions]], [[ Virology]], [[ Microbes and More]], [[ Biochemistry Research" id="metakeywords]] <li>List of numerical analysis software <br /li>[http: </ul> </siteanalytics.compete.comtd> </sciencedaily.com tr> <font size="1"/tbody><strong/table>Visitors</strongp><p> </fontp>] | [http://www.alexa.com/data/details/main?url=sciencedaily.com <font sizeh3><span class="1mw-headline">Related fields<strong/span>Alexa</strongh3></fontp>] | [http://whois.domaintools.com/sciencedaily.com <font sizetable> <tbody> <tr> <td valign="1top"> <ul> <strongli>Domain informationApplied mathematics </strongli> <li>Artificial intelligence </fontli>] | [http: <li>Biology </li> <li>Cheminformatics </www.iwebtool.comli> <li>Computational biology </toolli> </toolsul> </rank/rank.php?domain=sciencedaily.com td> <font sizetd valign="1top"> <strongul>Iwebtool </strongli>Computational science </fontli>] <li>Computer science </li> <li>Cybernetics </li> <li>Informatics </li> <li>Mathematical biology </li> </ul> <br /td> <a hreftd valign="http:top"> <ul> <li>Neuroinformatics </li> <li>Scientific computing </li> <li>Statistics </siteanalyticsli> <li>Systems biology </li> <li>Theoretical biology </li> </ul> </td> </tr> </tbody></table></p><p> </p><h2><span class="mw-headline">References</span></h2><ul> <li>Aluru, Srinivas, ed. <em>Handbook of Computational Molecular Biology</em>. Chapman & Hall/Crc, 2006.compete.com<a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=1584884061"><font color="#0066cc">ISBN 1584884061</font></a> (Chapman & Hall/Crc Computer and Information Science Series) </li> <li>Baldi, P and Brunak, S, <em>Bioinformatics: The Machine Learning Approach</em>, 2nd edition. MIT Press, 2001. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=026202506X"><font color="#0066cc">ISBN 0-262-02506-X</font></a> </li> <li>Barnes, M.R. and Gray, I.C., eds., <em>Bioinformatics for Geneticists</em>, first edition. Wiley, 2003. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0470843942"><font color="#0066cc">ISBN 0-470-84394-2</font></a> </li> <li>Baxevanis, A.D. and Ouellette, B.F.F., eds., <em>Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins</em>, third edition. Wiley, 2005. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0471478784"><font color="#0066cc">ISBN 0-471-47878-4</font></a> </li> <li>Baxevanis, A.D., Petsko, G.A., Stein, L.D., and Stormo, G.D., eds., <em>Current Protocols in Bioinformatics</em>. Wiley, 2007. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0471250937"><font color="#0066cc">ISBN 0-471-25093-7</font></a> </li> <li>Claverie, J.M. and C. Notredame, <em>Bioinformatics for Dummies</em>. Wiley, 2003. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0764516965"><font color="#0066cc">ISBN 0-7645-1696-5</font></a> </li> <li>Cristianini, N. and Hahn, M. <a class="external text" title="http://www.computational-genomics.net/" rel="nofollow" href="http://www.computational-genomics.net/"><em><font color="#0066cc">Introduction to Computational Genomics</font></em></a>, Cambridge University Press, 2006. (<a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=9780521671910"><font color="#0066cc">ISBN 9780521671910</font></a> | <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0521671914"><font color="#0066cc">ISBN 0521671914</font></a>) </li> <li>Durbin, R., S. Eddy, A. Krogh and G. Mitchison, <em>Biological sequence analysis</em>. Cambridge University Press, 1998. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0521629713"><font color="#0066cc">ISBN 0-521-62971-3</font></a> </li> <li>Gilbert, D. <a class="external text" title="http://bib.oxfordjournals.org/cgi/content/abstract/5/3/300" rel="nofollow" href="http://bib.oxfordjournals.org/cgi/content/abstract/5/3/300"><em><font color="#0066cc">Bioinformatics software resources</font></em></a>. Briefings in Bioinformatics, Briefings in Bioinformatics, 2004 5(3):300-304. </li> <li>Keedwell, E., <em>Intelligent Bioinformatics: The Application of Artificial Intelligence Techniques to Bioinformatics Problems</em>. Wiley, 2005. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0470021756"><font color="#0066cc">ISBN 0-470-02175-6</font></a> </li> <li>Kohane, et al. <em>Microarrays for an Integrative Genomics.</em> The MIT Press, 2002. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=026211271X"><font color="#0066cc">ISBN 0-262-11271-X</font></a> </li> <li>Lund, O. et al. <em>Immunological Bioinformatics.</em> The MIT Press, 2005. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0262122804"><font color="#0066cc">ISBN 0-262-12280-4</font></a> </li> <li>Michael S. Waterman, <em>Introduction to Computational Biology: Sequences, Maps and Genomes</em>. CRC Press, 1995. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0412993910"><font color="#0066cc">ISBN 0-412-99391-0</font></a> </li> <li>Mount, David W. <em>Bioinformatics: Sequence and Genome Analysis</em> Spring Harbor Press, May 2002. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0879696087"><font color="#0066cc">ISBN 0-87969-608-7</font></a> </li> <li>Pachter, Lior and <a title="Bernd Sturmfels" href="http://en.wikipedia.org/wiki/Bernd_Sturmfels"><font color="#0066cc">Sturmfels, Bernd</font></a>. "Algebraic Statistics for Computational Biology" Cambridge University Press, 2005. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0521857007"><font color="#0066cc">ISBN 0-521-85700-7</font></a> </li> <li>Pevzner, Pavel A. <em>Computational Molecular Biology: An Algorithmic Approach</em> The MIT Press, 2000. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&isbn=0262161974"><font color="#0066cc">ISBN 0-262-16197-4</font></a> </li></ul><p> </p><h2><span class="mw-headline">External links</span></h2><div class="infobox sisterproject"><div style="FLOAT: left"><div class="floatnone"><span><a class="image" title="" href="http://en.wikipedia.org/wiki/Image:Wiktionary-logo-en.png"></a></span></div></div><div style="MARGIN-LEFT: 60px"><div class="infobox sisterproject"><div style="MARGIN-LEFT: 60px"><div style="MARGIN-LEFT: 10px"><a class="extiw" title="v:Topic:Bioinformatics" href="http://en.wikiversity.org/wiki/Topic:Bioinformatics"><font color="#0066cc"></font></a></div></div></div></div></div><ul> <li> <ul> <li><a class="external text" title="http://bioinformatics.org/" rel="nofollow" href="http://bioinformatics.org/"><font color="#0066cc">Bioinformatics Organization (Bioinformatics.Org): The Open-Access Institute</font></a> </li> <li><a class="external text" title="http://www.embnet.org/" rel="nofollow" href="http://www.embnet.org/"><font color="#0066cc">EMBnet</font></a> </li> <li><a class="external text" title="http://www.ebi.ac.uk/" rel="nofollow" href="http://www.ebi.ac.uk/"><font color="#0066cc">European Bioinformatics Institute</font></a> </li> <li><a class="external text" title="http://www.embl.org/" rel="nofollow" href="http://www.embl.org/"><font color="#0066cc">European Molecular Biology Laboratory</font></a> </li> <li><a class="external text" title="http://www.iscb.org/" rel="nofollow" href="http://www.iscb.org/"><font color="#0066cc">The International Society for Computational Biology</font></a> </li> <li><a class="external text" title="http://www.ncbi.nlm.nih.gov/" rel="nofollow" href="http://www.ncbi.nlm.nih.gov/"><font color="#0066cc">National Center for Biotechnology Information</font></a> </li> <li><a class="external text" title="http://www.nih.gov" rel="nofollow" href="http://www.nih.gov/"><font color="#0066cc">National Institutes of Health homepage</font></a> </li> <li><a class="external text" title="http://www.open-bio.org/" rel="nofollow" href="http://www.open-bio.org/"><font color="#0066cc">Open Bioinformatics Foundation: umbrella non-profit organization supporting certain open-source projects in bioinformatics</font></a> </li> <li><a title="Swiss Institute of Bioinformatics" href="http://en.wikipedia.org/wiki/Swiss_Institute_of_Bioinformatics"><font color="#0066cc">Swiss Institute of Bioinformatics</font></a> </li> <li><a title="Wellcome Trust Sanger Institute" href="http://en.wikipedia.org/wiki/Wellcome_Trust_Sanger_Institute"><font color="#0066cc">Wellcome Trust Sanger Institute</font></a> </li> </ul> </li></ul><ul> <li>Major Journals <ul> <li><a class="external text" title="http://www.almob.org/" rel="nofollow" href="http://www.almob.org/"><font color="#0066cc">Algorithms in Molecular Biology</font></a> </li> <li><a class="external text" title="http://bioinformatics.oupjournals.org/" rel="nofollow" href="http://bioinformatics.oupjournals.org/"><font color="#0066cc">Bioinformatics journal</font></a> </li> <li><a class="external text" title="http://www.biomedcentral.com/bmcbioinformatics" rel="nofollow" href="http://www.biomedcentral.com/bmcbioinformatics"><font color="#0066cc">BMC Bioinformatics journal</font></a> </li> <li><a class="external text" title="http://bib.oxfordjournals.org/" rel="nofollow" href="http://bib.oxfordjournals.org/"><font color="#0066cc">Briefings in Bioinformatics</font></a> </li> <li><a class="external text" title="http://www.la-press.com/evolbio.htm" rel="nofollow" href="http://www.la-press.com/evolbio.htm"><font color="#0066cc">Evolutionary Bioinformatics</font></a> </li> <li><a class="external text" title="http://www.genome.org" rel="nofollow" href="http://www.genome.org/"><font color="#0066cc">Genome Research</font></a> </li> <li><a class="external text" title="http://www.bepress.com/ijb/" rel="nofollow" href="http://www.bepress.com/ijb/"><font color="#0066cc">The International Journal of Biostatistics</font></a> </li> <li><a class="external text" title="http://www.liebertpub.com/publication.aspx?pub_id=31" rel="nofollow" href="http://www.liebertpub.com/publication.aspx?pub_id=31"><font color="#0066cc">Journal of Computational Biology</font></a> </li> <li><a class="external text" title="http://www.nature.com/msb/index.html" rel="nofollow" href="http://www.nature.com/msb/index.html"><font color="#0066cc">Molecular Systems Biology</font></a> </li> <li><a class="external text" title="http://compbiol.plosjournals.org" rel="nofollow" href="http://compbiol.plosjournals.org/"><font color="#0066cc">PLoS Computational Biology</font></a> </li> <li><a class="external text" title="http://www.bepress.com/sagmb/" rel="nofollow" href="http://www.bepress.com/sagmb/"><font color="#0066cc">Statistical Applications in Genetic and Molecular Biology</font></a> </li> </ul> </li></ul><ul> <li>Other sites <ul> <li><a class="external text" title="http://www.biostatsresearch.com/repository/" rel="nofollow" href="http://www.biostatsresearch.com/repository/"><font color="#0066cc">The Collection of Biostatistics Research Archive</font></a> </li> <li><a class="external text" title="http://www.ornl.gov/TechResources/Human_Genome/research/informatics.html" rel="nofollow" href="http://www.ornl.gov/TechResources/Human_Genome/research/informatics.html"><font color="#0066cc">Human Genome Project and Bioinformatics</font></a> </li> <li><a class="external text" title="http://dmoz.org/Science/Biology/Bioinformatics/Research_Groups/" rel="nofollow" href="http://dmoz.org/Science/Biology/Bioinformatics/Research_Groups/"><font color="#0066cc">List of Bioinformatics Research Groups</font></a> at the <a title="Open Directory Project" href="http://en.wikipedia.org/wiki/Open_Directory_Project"><font color="#0066cc">Open Directory Project</font></a> </li> </ul> </li></ul><p><br /><br /></p><p>[http://bioinformatics.ws Bioinformatics.ws] | [http://biomics.org Biomics.org]<br /><br /><br /><br /><br /sciencedaily.com?metric=uv"><img alt="" src="http://home.compete.com.edgesuite.net/sciencedaily.com_uv_310.png" /></a><br /><br /p>