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GST 융합단백질의 발현과 정제

101 bytes added, 05:21, 9 March 2007
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본 항에서는 융합단백질의 발현 및 정제와 융합단백질로부터 GST domain을 잘라내어 목적단백질을 얻는 수법에 관해서 알아 보고자 한다.&nbsp;<br />
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</font><font size="2"><strong><br /><font style="BACKGROUND-COLOR: #ff99cc">Purification of GST-protein from E.Coli<br /></font></strong><br />
Lysis buffer<br />
-100mM Tris-HCl, pH 7.6, 100mM NaCl, 1 mM EDTA, 1 mg/ml lysozyme, 1 mM DTT, 1 ㎍/ml of pepstatin, leupeptin<br />
15. Frozen in aliquots at -80 oC.<br />
&nbsp;</font></p>
<p><font size="2"><strong><font style="BACKGROUND-COLOR: #ff99cc">GST pull-down<br /></font></strong><br />
Lysis Buffer <br />
&nbsp;&nbsp; -50 mM Tris, pH 7.6, 150 mM NaCl, 10 mM EDTA, 10 mM sodium pyrophosphate, 10 mM NaF, 1mM sodium orthovadate, 10 ㎍/ml of pepstatin, leupeptin, and AEBSF each, 1% NP-40.<br />
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