<p><font size="3"><em><strong><br />Complex phenotypes and genome variation :</strong><br /></em><font color="#ff0000">Risks of major common diseases</font> such as cancer, cardiovascular disease, <br />mental illness, auto-immune states, and diabetes, are expected to be heavily<br />influenced by the patterns of <font color="#ff0000">SNPs one possesses in certain key susceptibility <br />genes yet to be identified.&nbsp;<br /></font></font></p>

<p><font size="3"><em><strong><br />SNP based association studies :</strong></em><br />If a factor contributes an increased risk for disease occurrence, <font color="#ff0000">then that factor <br />should be found at higher frequency in individuals with that disease</font> compared to <br />non-diseased controls </font></p>