FAS Signaling Pathway(CD95)
|
|
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|
FAS |
FAS-L |
|
FAS |
DAXX |
|
FAS |
FAF |
|
FAS |
FADD |
|
FASLG |
FAS |
|
JUN |
JNK1 |
|
CAD |
ICAD |
|
CAD |
DNA Fragmentation |
|
RB1 |
PARP |
|
RB1 |
CASPASE3 |
|
LMNA |
LAMINb1 |
|
LMNA |
LAMINb2 |
|
LMNA |
CASPASE6 |
|
LMNB2 |
LMNB1 |
|
LMNB2 |
CASPASE6 |
|
FAP |
FAF |
|
FAP |
PRO-CASPASE8 Complex |
|
FAP |
I-FLICE |
|
LMNB1 |
LANA |
|
LMNB1 |
LMNB2 |
|
LMNB1 |
CASPASE6 |
|
CASP3 |
CASP6 |
|
CASP3 |
PAK1-PAK2 Complex |
|
CASP3 |
PARP |
|
CASP7 |
CASP8 |
|
CASP7 |
CASP10 |
|
CASP7 |
MEKK1 |
|
CASP8 |
CASP3 |
|
CASP8 |
CASP7 |
|
CASP8 |
PRO-CASPASE Complex |
|
CASP10 |
FADD |
|
CASP10 |
CASP7 |
|
FADD |
FAF |
|
FADD |
DAXX |
|
FADD |
FAS |
|
FAF |
FADD |
|
FAF |
FAS |
|
FAF |
FAP |
|
DAXX |
FAS |
|
DAXX |
FADD |
|
DAXX |
JNKK1 |
|
PAK1 |
PAK2 |
|
PAK1 |
MEKK1 |
|
PAK1 |
CASPASE3 |
|
PAK2 |
PAK1 |
|
PAK2 |
MEKK1 |
|
RIPK2 |
I-FLICE |