Cadmium induces DNA synthesis and proliferation in macrophages
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_cdmacPathway.gif
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NFkB |
IkBa |
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NFkB |
IL4 Pathway |
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NFkB |
IL10 Pathway |
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NFkB |
Cell Proliferation |
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NFkB |
Reduced Phagocytic Activity |
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NFkB |
PKC |
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PKC |
RAS |
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PKC |
NFkB |
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PKC |
Ca2+ |
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PLCb |
Putative Cd2+ Binding Protein? |
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PLCb |
PIP2 |
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RAF1 |
RAS |
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RAF1 |
MEK |