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Complement Pathway

http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_compPathway.gif

 

 

C3

F6

C3

H2O

C3

C3b

C3

MBL/MBP Complex

MASP2

MBL/MBP Complex

MASP2

MASP1

MBL2

MBP

MBL2

MASP-1

MBL2

MASP2

MBL2

carbohydrates

C1QA

C1r

C1QA

C1S

C1QA

C4

C1R

C1q

C1R

C1S

C1S

C1q

C1S

C1r

C6

C9

C6

C7

C7

C6

C7

C8

C8

C7

MASP1

MBL/MBP

MASP1

MASP2

MASP1

Carbohydrates

C2

C4b

C5

C5b

C5

C3b

C5

Bb-C3b Complex