CD151-165
|
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
| CD151 | 32 | PETA-3, SFA-1 | Platelets, megakaryocytes, immature hematopoeitic cells, endothelial cells | Adhesion molecule |
| CD152 | ~46, ~50 | Cytotoxic T lymphocyte-associated protein-4 (CTLA-4) | Activated T cells, perhaps some activated B cells | Negative regulator of T-cell activation |
| CD153 | 38-40 | CD30 ligand, CD30L | Activated T cells, activated macrophages, neutrophils, B cells | Ligand for CD30, may co-stimulate T cells |
| CD154 | 30 | CD40 ligand (CD40L), T-BAM, TNF-related activation protein (TRAP), gp39 | Activated CD4 cells | Ligand for CD40, inducer of B-cell proliferation and activation |
| CD155 | 80-90 | Poliovirus receptor (PVR) | Monocytes, macrophages, thymocytes, CNS neurons | Normal function unknown; receptor for poliovirus |
| CD156 | 69 | ADAM8, MS2 human | Neutrophils, monocytes | Possible role in extravasation of leukocytes |
| CD157 | 42-45, 50 | BP-3/IF-7, BST-1, Mo5 | Granulocytes, monocytes, macrophages, some B-cell progenitors, some T-cell progenitors | Support for growth of pymphocyte progenitors |
| CD158a | 58, 50 | EB6, MHC class Ⅰ- specific receptors, p50,1, p58.1 | Subset of NK cell, some T cells | Regulation of NK cell-mediated cytolytic activity upon interaction with the appropriate HLA-C alleles |
| CD158b | 58, 50 | GL183, MHV vlass Ⅰ-specific receptors, p50.2, p58.2 | Subset of NK cells, some T cells | Regulation of NK cell-mediated cytolytic activity upon interaction with the appropriate HLA-C alleles |
| CD161 | ~80 | NKR-PIA | Most NK cells, a subset of CD4+ and CD8+ T cells, thymocytes | Modulation of NK cell-mediated cytotoxicity against certain Fc-receptor-bearing targets; induction of immature thymocyte proliferation |
| CD162 | 250, 160, 220 | PSGL-1 | Most peripheral-blood T cells, monocytes, granulocytes, B cells | Mediation of leukocyte rolling |
| CD163 | 130 | GHI/61, M130 | Not known | Not known |
| CD164 | 80 | MUC-24, multi-glycosylated core protein 24 (MGC-24v) | Not known | Not known |
| CD165 | 37 | AD2, gp37 | Peripheral lymphocytes, immatyre thymocytes, monocytes, most platelets, thymocytes | Adhesive interactions including adhesion between thymocytes and thymic epithelial cells |