CD136-150
|
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
| CDw136 | 180 | Macrophage-stimulating protein receptor (msp receptor), ron (p158-ron) | Monocytes; epithelial tissues including skin, kidney, lung, liver, intestine, amd colon | Induction off migration, morphological change, and proliferation in different target cells |
| CDw137 | 85 | 4-1BB, induced by lymphocyte activation (ILA) | T cells, B cells, monocytes | Co-stimulation of T-cell proliferation |
| CD138 | MW not known | Heparin sulfate proteoglycan, syndecan-1 | B cells | Binding to collagen type 1 |
| CD139 | 209, 228 | B cells, monocytes, granulocytees, follicular dendritic cells | Not known | |
| CD140a | 180 | PDGF receptor (PDGF-R), PDGFR, α platelet-derived growth-factor receptor (PDGFRa) | Some endothelial cells | Receptor for platelet-derived growth factor (PDGF) |
| CD140b | 180 | β platelet-derived growth factor receptor (PDGFRb) | Some endothelial cells | Receptor for platelet-derived growth factor (PDGF) |
| CD141 | 75 | Fetomodulin, thrombomodulin (TM) | Endothelial cells, megakaryocytes, platelets, monocytes, neutrophils | Essential molecule for activation of protein C and initiation of the protein C anticoagulant pathway |
| CD142 | 45-47 | Coagulation FactorⅢ, theomboplastin, tissue factor (TF) | Inducible on monocytes and vascular endothelial cells by various inflammatory mediators | Aid in establishing environment favoring coagulation |
| CD143 | 170, 180, 90, 110 | EC3.4.15.1, antiotensin-converting enzyme (ACE), kinaseⅡ, prptidyl dipeptidase A | Endothelial cells, activated macrophages, some T cells | An enzyme, important in regulation of blood pressure, acts primarily as a peptidyl dipeptide hydrolase and is invloved in the metabolism of two major vasoactive peptides, angiotensin Ⅱ and bradykinin |
| CD144 | 135 | Cadherin-5 VE-cadherin | Endothelium | Control of endothelial cell-cell adhesion, permeability, and migration |
| CDw145 | MW not known | Not known | Not known | |
| CD146 | 118 | A32, MCAM, MUC18, mel-CAM, S-endo | Endothelium, a subpopulation of activated T cells | Potential adhesion molecule |
| CD147 | 50-60 | 5A11, basigin, CE9, HT7, M6, neurothelin, OX-47, extracellular-matrix metalloproteinase inducer (EMMPRIN), gp42 in mouse | All leukocytes, red blood cells, platelets, and endothelial cells | Adhesion molecule |
| CD148 | 240-260, 200-250 | HPTP-eta, high-cell density-enhanced PTP1 (DEP-1), p260 | Granulocytes, monocytes, T cells, dendritic cells, platelets | Contact inhibition of cell growth |
| CDw149 | 120 | MEM-133 | Peripheral-blood lymphocytes, monocytes, neutrophils, eosinophils, platelets | Not known |
| CDw150 | 75-95, 70 | IPO-3, signaling lynphocyte activation molecule (SLAM) | Thymocytes, subpopulation of T cells, B cells, dendritic cells, endothelial cells | B-cell co-stimulation |