|
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
| CDw76 | Carbohydrate antigen | B cells, subpopulation of T cells | Not known | |
| CD77 | Pk blood group antigen, Burkitt's lymphoma antigen, (BLA), ceramide trihexoside (CTH), globotriaosylceramide (Gb3); sphingolipid antigen | Germinal-center B cells | Not known | |
| CD79a | 40-45 | Ig-α, MB1 | B cells | Component of B-cell antigen receptor analogous to CD3, required for cell-surface expression and signal transduction |
| CD79b | 37 | B29, Ig-β | B cells | Component of B-cell antigen receptor analogous to CE3, required for cell-surface expression and signal transduction |
| CD80 | 60 | B7, B7.1, BB1 | Activated B and T cells; macrophages | Co-stimulation of T-cell activation with CD86 |
| CD81 | 26 | Target for anti-proliferative antigen-1 (TAPA-1) | Broadly expressed on hematopoeitic cells; expressed by endothelial and epithelial cells; absent from erythrocytes, platelets, and neutrophils | Member of CD19/CD21/Leu-13 signal-transduction complex, the B-cell co-receptor |
| CD82 | 45-90 | 4F9, C33, IA4, KAI1, R2 | Activated/differentiated hematopoeitic cells | Signal transduction: may induce T-cell spreading and pseudopod formation, modulate T-cell proliferation, and provide co-stimulatory signals for cytokine production; possible role in activation of monocytes |
| CD83 | 43 | HB15 | Dendritic cells, B cells, Langerhans cells | Not known |
| CD84 | 73 | GR6 | Monocytes, platelets, circulating B cells | Not known |
| CD85 | 110 | GR4 | Plasma cells, mantle-zone and germinal-center B cells, subpopulation of peripheral-blood NK cells | Possible role in T-cell activation in peripheral blood |
| CD86 | ||||
| CD87 | ||||
| CD88 | ||||
| CD89 | ||||
| CD90 |