CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
CD1a, b, c, d, e | 43-49 | MHC class I-like structure | Dendritic cells, B cells, Langerhans cells, some thymocytes | Display of non-peptide and glycolipid antigens for T-cell responses |
CD2 | 45-58 | LFA-2, T11, E-rosette receptor; CD58 binding adhesion molecule | T cells, thymocytes, NK cells | Adhesion molecule involved in T-cell activation |
CD3 | γ; 25-28δ; 20ε; 20 |
T3; composed of 3 polypeptide chains: γ, δ, ε | Thmocytes, T cells, NK1-T cells | Essential role in TCR signal transduction and in cell-surface expression of the TCR |
CD4 | 55 | L3T4 | MHC class Ⅱ-restricted T cells, some thymocytes, monocytes/macrophage, granulocytes | Co-receptor for MHC class Ⅱ-restricted T-cell activation; thymic differentiation marker for T cells; receptor for HIV |