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CD 항원(CD antigen)

Revision as of 12:56, 4 September 2006 by Ihjung (talk | contribs)

 CD antigen

 MW.(kDa) 

 Synonyms & Properties

 Leukocyte expression  

 Function

CD1a, b, c, d, e  43-49  MHC class I-like structure  Dendritic cells, B cells,  Langerhans cells, some thymocytes  Display of non-peptide and glycolipid antigens for T-cell responses
CD2  45-58  LFA-2, T11, E-rosette receptor; CD58 binding adhesion molecule  T cells, thymocytes, NK cells  Adhesion molecule involved in T-cell activation
CD3 γ; 25-28
           δ; 20
ε; 20 
 T3; composed of 3 polypeptide chains: γ, δ, ε  Thmocytes, T cells, NK1-T cells  Essential role in TCR signal transduction and in cell-surface expression of the TCR
CD4  55  L3T4  MHC class Ⅱ-restricted T cells, some thymocytes, monocytes/macrophage, granulocytes   Co-receptor for MHC class Ⅱ-restricted T-cell activation; thymic differentiation marker for T cells; receptor for HIV