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Insight: Stem Cells
VolVol. 441, NoNo. 7097 pppp1059-1102
In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease.
This Nature Insight is accompanied by a special stem cells podcast, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field.
Readers are invited to join an web forum to exchange views and opinions raised by the Insight articles. There is also a podcast forum for issues discussed in the stem cells podcast.
Editorial
Stem-cell Biology Free access
Natalie DeWitt
doidoi:10.1038/4411059a
Abstract |Full Text | PDFPDF (164KBKB)
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Glossary
A glossary for stem-cell biology Free access
Austin Smith
doidoi:10.1038/nature04954
Abstract |Full Text | PDFPDF (68KBKB)
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Reviews
Nuclear reprogramming and pluripotency Free access
Konrad Hochedlinger and Rudolf Jaenisch
doidoi:10.1038/nature04955
Abstract | Full Text | PDFPDF (644KBKB)
Asymmetric and symmetric stem-cell divisions in development and cancer Free access
Sean J. Morrison and Judith Kimble
doidoi:10.1038/nature04956
Abstract | Full Text | PDFPDF (473KBKB)
The stem-cell niche as an entity of action Free access
David T. Scadden
doidoi:10.1038/nature04957
Abstract | Full Text | PDFPDF (323 KBKB)
Stem cells, ageing and the quest for immortality Free access
Thomas A. Rando
doidoi:10.1038/nature04958
Abstract | Full Text | PDFPDF (641 KBKB)
Generation of neuronal variability and complexity Free access
Alysson R. Muotri and Fred H. Gage
doidoi:10.1038/nature04959
Abstract | Full Text | PDFPDF (756 KBKB)
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Progress
Stem cells for the treatment of neurological disorders Free access
Olle Lindvall and Zaal Kokaia
doidoi:10.1038/nature04960
Abstract | Full Text | PDFPDF (402KBKB)
Potential of stem-cell-based therapies for heart disease Free access
Deepak Srivastava and Kathryn N. Ivey
doidoi:10.1038/nature04961
Abstract | Full Text | PDFPDF (345 KBKB)
Stem-cell therapies for blood diseases Free access
Claudio Bordignon
doidoi:10.1038/nature04962
Abstract | Full Text | PDFPDF (323 KBKB)