G-Secretase mediated ErbB4 Signaling Pathway

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ERBB4

TPA/NRG 2,3,4

ERBB4

PKC

ERBB4

NRG2-ErbB4 Complex

ADAM17

Bb-94

ADAM17

PKC

NRG3

ErbB4

PRKCA

ErbB4-TPA/NRG 2, 3, 4 Complex

PRKCA

ADAM17/TACE