Granzyme A mediated Apoptosis Pathway

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GZMA

GZMA

GZMA

SET

GZMA

HMG2

GZMA

Ape1

GZMB

Caspase Activation

APEX1

PP32

APEX1

APE1

APEX1

SET

APEX1

HMG2

CAD

DNA Fragment

CAD

ICAD

NME1

SET

NME1

APe1

NME1

PP32

NME1

DAN Nicks

SET

APe1

SET

HMG2

SET

Chromatin Structure

SET

DNA repair

SET

Transcriptional Regulation

SET

GZMA

HMGB2

PP32

HMGB2

SET

HMGB2

APe1

HMGB2

GZMA
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