CD166-180

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 CD antigen

 MW.(kDa) 

 Synonyms & Properties

 Leukocyte expression  

 Function

 CD166  100-105  BEN, DM-GRASP, KG-CAM, neurolin, SC-1, activated-leukocyte cell-adhesion molecule (ALCAM)   Activated T cells, activated monocytes, epithelium, neurons, fibroblasts   Adhesion molecule that binds to CD6 
 CD167  α subunit 54, β subunit 63  DDR1 (discoidin domain family member 1)   Mainly normal and transformed epithelial cells    Receptor tyrosine kinase activated by various types of collagen 
 CD168  85-95  RHAMM (receptor for hyaluronan-mediated motility)   Some fibroblast cell lines, lymphovytes, hematopoietic progenitor cells and malignant B lymphocytes   Expressed on a hyaluronan-binding receptor that participates in the hyaluronan-dependent motility of thymocytes, lymphocytes, hematopoeitic progenitor cells, and malignant B lymphocytes 
 CD169  220  SIGLEC-1 (sialic acid   ctin-1); Sialoadhesion  Macrophages   Mediates cell-cell interactions by binding to sialylated ligands on neutrophils, monocytes, NK cells, B cells, and a subset of CD8+ T cells 
 CD170  140  SIGLEC-5 (sialic acid binding Ig-like lectin-1)   Relatively high levels on neutrophils   May be involved in sialic acid-dependent cell-cell interactions 
 CD171  200-230  L1 cell adhesion molecule   Low to intermediate expression on human lymphoid and myelomonocytic cells including CD4+ T cells, a subset of B cells, monocytes, monocyte-derived dendritic cells, many cells of the central and peripheral nervous system   Cell adhesion molecule that plays a role in the maintenance of pymph node architecture during an immune response 
 CD173    H2, blood group O antigen   Among hematopoietic cells, present on erythrocytes and CD34+ hematopoietic precursors   Glycoprotein-borne oligosaccharide 
 CD174    Lewis Y blood group antigen  Among hematopoietic cells, present on erythrocytes and CD34+ hematopoietic precursors   Glycoprotein-borne oligosaccharide 
 CD177  58-64  NB1   Surfaces and secondary granules of neutrophils  Glycoprotein 
 CD178  Monomer of cell surface form 40; soluble forms 26-30  Fas ligand, FasL  Constitutive or induced expression on many cell types including T cells, NK cells, microglial cells, neutrophils, nonhematopoietic cells such as retinal and corneal parenchymal cells   Not known 
 CD179a  16-18  VpreB   Selectively expressed in pro-B and early pre-B cells   Associates with CD 179b to form surrogate light chain if the preB cell receptor 
 CD179b  22  Lambda5   Selectively expressed  in pro-B and early pre-B cells   Associates with CD 179a to form surrogate light chain if the preB cell receptor 
 CD180  95-105  RP105, LY64   Monocytes, dendritic cells, mantle zone B cells   Not known