Calcium Signaling by HBx of Hepatitis B virus

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http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_hbxPathway.gif 

   

SRC

Pyk2

SRC

HBV DNA Replication

GRB2

SHC

GRB2

RAS

GRB2

SOS-1

SHC

GRB2

SHC

Pyk2-SRC Complex

CREb

HBX

CREb

Gene expression inhibitor

HBXIP

HBX-Mitochondria complex

HBXIP

HBX-CREb complex


Transcription factor
-CREb