ATM Signaling Pathway
From Opengenome.net
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_atmPathway.gif
Pathway Interaction
|
CHK1 |
ATM |
|
|
p53-mdm2 |
|
CHK2 |
ATM |
|
p53 |
p21 |
|
|
GADD45 |
|
|
mdm2 |
|
|
Apoptosis |
|
p73 |
C-Ab1 |
|
|
Apoptosis |
|
ATM |
CHK2 |
|
|
CHK1 |
|
|
RPA |
|
|
C-Abl |
|
|
mdm2 |
|
|
CTIP |
|
|
NFkB |
|
|
p53 |
|
NFkB |
IKBa |
|
|
Apoptosis |
|
|
ATM |
|
RAD51 |
CAD1 |
|
|
BRCA1 |
|
BRCA1 |
GADD45 |
|
|
Rad51 |
|
MDM2 |
p53, ATM |
|
|
BRCA1 |
|
JUN |
SAPK1 |
| RAD50 | nibrin |
| Mre11 |
