Activation of Src by protein tyrosine phosphatase alpha

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Revision as of 15:04, 16 August 2006 by Hj-Roh (talk | contribs)

http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_srcRPTPPathway.gif

Cell cycle을 통한 progression은 proto-ancogene C-Src의 활성화에 의해서 수행되는 protein tyrosine kinase이다.
Src의 overexproession은 multiple protein substrates의 tyrosine phosphorylation과 세포의 transformation을 가지고 온다.