Difference between revisions of "Caspase Cascade in Apoptosis"
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| − | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_caspasePathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_caspasePathway.gif</a> | + | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_caspasePathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_caspasePathway.gif</a> <br /> |
| + | <br /> | ||
| + | <table style="WIDTH: 695px; HEIGHT: 773px" cellspacing="1" cellpadding="1" width="695" summary="" border="1"> | ||
| + | <tbody> | ||
| + | <tr> | ||
| + | <td> </td> | ||
| + | <td> </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASPASE4</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASPASE8</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP10</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">GRANZYME B</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP10</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP6</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP6</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">LAMIN B1-LAMINA-LAMIN B2 complex</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP2</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">LAMINA-LAMIN B2 complex</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GZMB</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP10</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GZMB</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GZMB</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP7</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GZMB</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">PERFORIN</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP8</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP6</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">SREBP</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">AP-24</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">D4-GDI</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">ICRD-CAD</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">LMNA</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">LMN B1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">LMNA</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">LMN B2</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GASP7</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">GRANZYME B</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GASP7</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP9</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">GASP7</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">XIAP-CLAP1-clAP</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">APRF-1</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Cytochrome c</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">APRF-a</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP 9</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP9</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP7</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP9</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">XIAP-clAP1-clAP</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">PRF</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">GRANZYME B</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">PARP</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP 3</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CYCS</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Apaf-1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">LMNB1</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASP6</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">LMNB2</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">LAMINA</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CAD</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">ICAD</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CAD</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">DNA Fragmentation</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> </td> | ||
| + | <td> </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> </td> | ||
| + | <td> </td> | ||
| + | </tr> | ||
| + | </tbody> | ||
| + | </table> | ||
| + | <br /> | ||
| + | Transcription factor<br /> | ||
| + | -CAD | ||
Latest revision as of 00:01, 27 August 2006
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_caspasePathway.gif
|
CASPASE4 |
CASP1 |
|
CASPASE8 |
CASP3 |
|
CASP10 |
GRANZYME B |
|
CASP10 |
CASP3 |
|
CASP6 |
CASP3 |
|
CASP6 |
LAMIN B1-LAMINA-LAMIN B2 complex |
|
CASP2 |
LAMINA-LAMIN B2 complex |
|
GZMB |
CASP10 |
|
GZMB |
CASP3 |
|
GZMB |
CASP7 |
|
GZMB |
PERFORIN |
|
CASP3 |
CASP8 |
|
CASP3 |
CASP1 |
|
CASP3 |
CASP6 |
|
CASP3 |
SREBP |
|
CASP3 |
AP-24 |
|
CASP3 |
D4-GDI |
|
CASP3 |
ICRD-CAD |
|
LMNA |
LMN B1 |
|
LMNA |
LMN B2 |
|
GASP7 |
GRANZYME B |
|
GASP7 |
CASP9 |
|
GASP7 |
XIAP-CLAP1-clAP |
|
APRF-1 |
Cytochrome c |
|
APRF-a |
CASP 9 |
|
CASP9 |
CASP7 |
|
CASP9 |
XIAP-clAP1-clAP |
|
PRF |
GRANZYME B |
|
PARP |
CASP 3 |
|
CYCS |
Apaf-1 |
|
LMNB1 |
CASP6 |
|
LMNB2 |
LAMINA |
|
CAD |
ICAD |
|
CAD |
DNA Fragmentation |
Transcription factor
-CAD
