Difference between revisions of "Nature Stem cell"

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<h2 class="insight" minmax_bound="true">Insight: Stem Cells</h2>
 
<h2 class="insight" minmax_bound="true">Insight: Stem Cells</h2>
<p class="volume" minmax_bound="true"><abbr title="volume" minmax_bound="true">Vol</abbr>VolVolVol. 441, <abbr title="Number" minmax_bound="true">No</abbr>NoNoNo. 7097 <abbr title="pages" minmax_bound="true">pp</abbr>pppppp1059-1102</p>
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<p class="volume" minmax_bound="true"><abbr title="volume" minmax_bound="true">Vol</abbr>VolVolVolVol. 441, <abbr title="Number" minmax_bound="true">No</abbr>NoNoNoNo. 7097 <abbr title="pages" minmax_bound="true">pp</abbr>pppppppp1059-1102</p>
 
<p class="norm" minmax_bound="true">[http://www.nature.com/nature/supplements/insights/stem_cells/images/cover.jpg]<br />In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. </p>
 
<p class="norm" minmax_bound="true">[http://www.nature.com/nature/supplements/insights/stem_cells/images/cover.jpg]<br />In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. </p>
 
<p class="norm" minmax_bound="true">This <span class="journalname" minmax_bound="true">Nature</span> Insight is accompanied by a special stem cells <a minmax_bound="true" href="http://www.nature.com/podcast/stemcells/index.html">podcast</a>, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field. </p>
 
<p class="norm" minmax_bound="true">This <span class="journalname" minmax_bound="true">Nature</span> Insight is accompanied by a special stem cells <a minmax_bound="true" href="http://www.nature.com/podcast/stemcells/index.html">podcast</a>, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field. </p>
 
<p class="norm" minmax_bound="true">Readers are invited to join an <a minmax_bound="true" href="http://blogs.nature.com/nature/insightstemcells/">web forum</a> to exchange views and opinions raised by the <span class="journalname" minmax_bound="true">Insight</span> articles. There is also a <a minmax_bound="true" href="http://blogs.nature.com/news/blog/podcasts/">podcast forum</a> for issues discussed in the stem cells podcast. </p>
 
<p class="norm" minmax_bound="true">Readers are invited to join an <a minmax_bound="true" href="http://blogs.nature.com/nature/insightstemcells/">web forum</a> to exchange views and opinions raised by the <span class="journalname" minmax_bound="true">Insight</span> articles. There is also a <a minmax_bound="true" href="http://blogs.nature.com/news/blog/podcasts/">podcast forum</a> for issues discussed in the stem cells podcast. </p>
 
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<h3 minmax_bound="true">In this supplement</h3>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem-cell Biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem-cell Biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Natalie DeWitt</p>
 
<p class="abs" minmax_bound="true">Natalie DeWitt</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/4411059a</p>
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<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/4411059a</p>
<p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/4411059a.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/4411059a.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/4411059a.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDF (164<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKB)</a></p>
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<p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/4411059a.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/4411059a.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/4411059a.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (164<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">A glossary for stem-cell biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">A glossary for stem-cell biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Austin Smith</p>
 
<p class="abs" minmax_bound="true">Austin Smith</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04954</p>
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<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04954</p>
<p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04954.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04954.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04954.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDF (68<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKB)</a></p>
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<p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04954.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04954.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04954.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (68<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Nuclear reprogramming and pluripotency</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Nuclear reprogramming and pluripotency</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Konrad Hochedlinger and Rudolf Jaenisch</p>
 
<p class="abs" minmax_bound="true">Konrad Hochedlinger and Rudolf Jaenisch</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04955</p>
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<p class="links" minmax_bound="true"><a class="abstract" title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04955.html">Abstract</a> | <a class="fulltext" title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04955.html">Full Text</a> | <a title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04955.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (644<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Asymmetric and symmetric stem-cell divisions in development and cancer</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Asymmetric and symmetric stem-cell divisions in development and cancer</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Sean J. Morrison and Judith Kimble</p>
 
<p class="abs" minmax_bound="true">Sean J. Morrison and Judith Kimble</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04956</p>
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<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04956</p>
<p class="links" minmax_bound="true"><a class="abstract" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04956.html">Abstract</a> | <a class="fulltext" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04956.html">Full Text</a> | <a title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04956.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDF (473<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKB)</a></p>
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<p class="links" minmax_bound="true"><a class="abstract" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04956.html">Abstract</a> | <a class="fulltext" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04956.html">Full Text</a> | <a title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04956.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (473<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">The stem-cell niche as an entity of action</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">The stem-cell niche as an entity of action</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">David T. Scadden</p>
 
<p class="abs" minmax_bound="true">David T. Scadden</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04957</p>
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<p class="links" minmax_bound="true"><a class="abstract" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04957.html">Abstract</a> | <a class="fulltext" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04957.html">Full Text</a> | <a title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04957.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDF (323 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKB)</a></p>
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<p class="links" minmax_bound="true"><a class="abstract" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04957.html">Abstract</a> | <a class="fulltext" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04957.html">Full Text</a> | <a title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04957.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (323 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells, ageing and the quest for immortality</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells, ageing and the quest for immortality</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Thomas A. Rando</p>
 
<p class="abs" minmax_bound="true">Thomas A. Rando</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04958</p>
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<p class="links" minmax_bound="true"><a class="abstract" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04958.html">Abstract</a> | <a class="fulltext" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04958.html">Full Text</a> | <a title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04958.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDF (641 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKB)</a></p>
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<p class="links" minmax_bound="true"><a class="abstract" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04958.html">Abstract</a> | <a class="fulltext" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04958.html">Full Text</a> | <a title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04958.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (641 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Generation of neuronal variability and complexity</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Generation of neuronal variability and complexity</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Alysson R. Muotri and Fred H. Gage</p>
 
<p class="abs" minmax_bound="true">Alysson R. Muotri and Fred H. Gage</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04959</p>
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<p class="links" minmax_bound="true"><a class="abstract" title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04959.html">Abstract</a> | <a class="fulltext" title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04959.html">Full Text</a> | <a title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04959.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (756 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells for the treatment of neurological disorders</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells for the treatment of neurological disorders</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
<p class="abs" minmax_bound="true">Olle Lindvall and Zaal Kokaia</p>
 
<p class="abs" minmax_bound="true">Olle Lindvall and Zaal Kokaia</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04960</p>
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<p class="links" minmax_bound="true"><a class="abstract" title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04960.html">Abstract</a> | <a class="fulltext" title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04960.html">Full Text</a> | <a title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04960.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (402<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p>
 
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Potential of stem-cell-based therapies for heart disease</span><span class="free-access" minmax_bound="true"> Free access</span></h4>
 
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<p class="abs" minmax_bound="true">Deepak Srivastava and Kathryn N. Ivey</p>
 
<p class="abs" minmax_bound="true">Deepak Srivastava and Kathryn N. Ivey</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04961</p>
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<p class="abs" minmax_bound="true">Claudio Bordignon</p>
 
<p class="abs" minmax_bound="true">Claudio Bordignon</p>
<p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoi:10.1038/nature04962</p>
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Revision as of 12:09, 30 June 2006

Supplements

Insight: Stem Cells

VolVolVolVolVol. 441, NoNoNoNoNo. 7097 pppppppppp1059-1102

[1]
In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease.

This Nature Insight is accompanied by a special stem cells podcast, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field.

Readers are invited to join an web forum to exchange views and opinions raised by the Insight articles. There is also a podcast forum for issues discussed in the stem cells podcast.

In this supplement

Top

Editorial

Stem-cell Biology Free access

Natalie DeWitt

doidoidoidoi:10.1038/4411059a


Top

Glossary

A glossary for stem-cell biology Free access

Austin Smith

doidoidoidoi:10.1038/nature04954


Top

Reviews

Nuclear reprogramming and pluripotency Free access

Konrad Hochedlinger and Rudolf Jaenisch

doidoidoidoi:10.1038/nature04955


Asymmetric and symmetric stem-cell divisions in development and cancer Free access

Sean J. Morrison and Judith Kimble

doidoidoidoi:10.1038/nature04956


The stem-cell niche as an entity of action Free access

David T. Scadden

doidoidoidoi:10.1038/nature04957


Stem cells, ageing and the quest for immortality Free access

Thomas A. Rando

doidoidoidoi:10.1038/nature04958


Generation of neuronal variability and complexity Free access

Alysson R. Muotri and Fred H. Gage

doidoidoidoi:10.1038/nature04959


Top

Progress

Stem cells for the treatment of neurological disorders Free access

Olle Lindvall and Zaal Kokaia

doidoidoidoi:10.1038/nature04960


Potential of stem-cell-based therapies for heart disease Free access

Deepak Srivastava and Kathryn N. Ivey

doidoidoidoi:10.1038/nature04961


Stem-cell therapies for blood diseases Free access

Claudio Bordignon

doidoidoidoi:10.1038/nature04962