Difference between revisions of "CD151-165"
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<tr> | <tr> | ||
<td><strong> CD151</strong></td> | <td><strong> CD151</strong></td> | ||
| − | <td> </td> | + | <td> 32</td> |
| − | <td> </td> | + | <td> PETA-3, SFA-1</td> |
| − | <td> </td> | + | <td> Platelets, megakaryocytes, immature hematopoeitic cells, endothelial cells</td> |
| − | <td> </td> | + | <td> Adhesion molecule </td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD152</strong></td> | <td bgcolor="#cccccc"><strong> CD152</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> ~46, ~50</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Cytotoxic T lymphocyte-associated protein-4 (CTLA-4)</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Activated T cells, perhaps some activated B cells </td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Negative regulator of T-cell activation</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td><strong> CD153</strong></td> | <td><strong> CD153</strong></td> | ||
| − | <td> </td> | + | <td> 38-40</td> |
| − | <td> </td> | + | <td> CD30 ligand, CD30L</td> |
| − | <td> </td> | + | <td> Activated T cells, activated macrophages, neutrophils, B cells</td> |
| − | <td> </td> | + | <td> Ligand for CD30, may co-stimulate T cells</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD154</strong></td> | <td bgcolor="#cccccc"><strong> CD154</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> 30</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> CD40 ligand (CD40L), T-BAM, TNF-related activation protein (TRAP), gp39</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Activated CD4 cells</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Ligand for CD40, inducer of B-cell proliferation and activation</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td><strong> CD155</strong></td> | <td><strong> CD155</strong></td> | ||
| − | <td> </td> | + | <td> 80-90</td> |
| − | <td> </td> | + | <td> Poliovirus receptor (PVR) </td> |
| − | <td> </td> | + | <td> Monocytes, macrophages, thymocytes, CNS neurons</td> |
| − | <td> </td> | + | <td> Normal function unknown; receptor for poliovirus</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD156</strong></td> | <td bgcolor="#cccccc"><strong> CD156</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> 69</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> ADAM8, MS2 human</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Neutrophils, monocytes</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Possible role in extravasation of leukocytes </td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td><strong> CD157</strong></td> | <td><strong> CD157</strong></td> | ||
| − | <td> </td> | + | <td> 42-45, 50</td> |
| − | <td> </td> | + | <td> BP-3/IF-7, BST-1, Mo5</td> |
| − | <td> </td> | + | <td> Granulocytes, monocytes, macrophages, some B-cell progenitors, some T-cell progenitors</td> |
| − | <td> </td> | + | <td> Support for growth of pymphocyte progenitors</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD158a</strong></td> | <td bgcolor="#cccccc"><strong> CD158a</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> 58, 50</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> EB6, MHC class Ⅰ- specific receptors, p50,1, p58.1</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Subset of NK cell, some T cells</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Regulation of NK cell-mediated cytolytic activity upon interaction with the appropriate HLA-C alleles</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td><strong> CD158b</strong></td> | <td><strong> CD158b</strong></td> | ||
| − | <td> </td> | + | <td> 58, 50</td> |
| − | <td> </td> | + | <td> GL183, MHV vlass Ⅰ-specific receptors, p50.2, p58.2 </td> |
| − | <td> </td> | + | <td> Subset of NK cells, some T cells</td> |
| − | <td> </td> | + | <td> Regulation of NK cell-mediated cytolytic activity upon interaction with the appropriate HLA-C alleles</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD161</strong></td> | <td bgcolor="#cccccc"><strong> CD161</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> ~80</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> NKR-PIA </td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Most NK cells, a subset of CD4+ and CD8+ T cells, thymocytes </td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Modulation of NK cell-mediated cytotoxicity against certain Fc-receptor-bearing targets; induction of immature thymocyte proliferation</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td><strong> CD162</strong></td> | <td><strong> CD162</strong></td> | ||
| − | <td> </td> | + | <td> 250, 160, 220</td> |
| − | <td> </td> | + | <td> PSGL-1</td> |
| − | <td> </td> | + | <td> Most peripheral-blood T cells, monocytes, granulocytes, B cells</td> |
| − | <td> </td> | + | <td> Mediation of leukocyte rolling</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD163</strong></td> | <td bgcolor="#cccccc"><strong> CD163</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> 130</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> GHI/61, M130 </td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Not known </td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Not known </td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td><strong> CD164</strong></td> | <td><strong> CD164</strong></td> | ||
| − | <td> </td> | + | <td> 80</td> |
| − | <td> </td> | + | <td> MUC-24, multi-glycosylated core protein 24 (MGC-24v) </td> |
| − | <td> </td> | + | <td> Not known </td> |
| − | <td> </td> | + | <td> Not known</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
<td bgcolor="#cccccc"><strong> CD165</strong></td> | <td bgcolor="#cccccc"><strong> CD165</strong></td> | ||
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> 37</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> AD2, gp37</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Peripheral lymphocytes, immatyre thymocytes, monocytes, most platelets, thymocytes</td> |
| − | <td bgcolor="#cccccc"> </td> | + | <td bgcolor="#cccccc"> Adhesive interactions including adhesion between thymocytes and thymic epithelial cells</td> |
</tr> | </tr> | ||
</tbody> | </tbody> | ||
</table> | </table> | ||
Latest revision as of 00:48, 12 September 2006
|
CD antigen |
MW.(kDa) |
Synonyms & Properties |
Leukocyte expression |
Function |
| CD151 | 32 | PETA-3, SFA-1 | Platelets, megakaryocytes, immature hematopoeitic cells, endothelial cells | Adhesion molecule |
| CD152 | ~46, ~50 | Cytotoxic T lymphocyte-associated protein-4 (CTLA-4) | Activated T cells, perhaps some activated B cells | Negative regulator of T-cell activation |
| CD153 | 38-40 | CD30 ligand, CD30L | Activated T cells, activated macrophages, neutrophils, B cells | Ligand for CD30, may co-stimulate T cells |
| CD154 | 30 | CD40 ligand (CD40L), T-BAM, TNF-related activation protein (TRAP), gp39 | Activated CD4 cells | Ligand for CD40, inducer of B-cell proliferation and activation |
| CD155 | 80-90 | Poliovirus receptor (PVR) | Monocytes, macrophages, thymocytes, CNS neurons | Normal function unknown; receptor for poliovirus |
| CD156 | 69 | ADAM8, MS2 human | Neutrophils, monocytes | Possible role in extravasation of leukocytes |
| CD157 | 42-45, 50 | BP-3/IF-7, BST-1, Mo5 | Granulocytes, monocytes, macrophages, some B-cell progenitors, some T-cell progenitors | Support for growth of pymphocyte progenitors |
| CD158a | 58, 50 | EB6, MHC class Ⅰ- specific receptors, p50,1, p58.1 | Subset of NK cell, some T cells | Regulation of NK cell-mediated cytolytic activity upon interaction with the appropriate HLA-C alleles |
| CD158b | 58, 50 | GL183, MHV vlass Ⅰ-specific receptors, p50.2, p58.2 | Subset of NK cells, some T cells | Regulation of NK cell-mediated cytolytic activity upon interaction with the appropriate HLA-C alleles |
| CD161 | ~80 | NKR-PIA | Most NK cells, a subset of CD4+ and CD8+ T cells, thymocytes | Modulation of NK cell-mediated cytotoxicity against certain Fc-receptor-bearing targets; induction of immature thymocyte proliferation |
| CD162 | 250, 160, 220 | PSGL-1 | Most peripheral-blood T cells, monocytes, granulocytes, B cells | Mediation of leukocyte rolling |
| CD163 | 130 | GHI/61, M130 | Not known | Not known |
| CD164 | 80 | MUC-24, multi-glycosylated core protein 24 (MGC-24v) | Not known | Not known |
| CD165 | 37 | AD2, gp37 | Peripheral lymphocytes, immatyre thymocytes, monocytes, most platelets, thymocytes | Adhesive interactions including adhesion between thymocytes and thymic epithelial cells |
