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<p><br /><br /><table style="WIDTH: 740px; HEIGHT: 348px" cellspacing="1" cellpadding="1" width="740" summary="" border="1"> <tbody> <tr> <td bgcolor="#999999"> <p align="center"><strong> <font color="#ffffff">CD antigen</font></strong></p> </td> <td bgcolor="#999999"> <p align="center"><strong><font color="#ffffff"> MW.(kDa) </font></strong></p> </td> <td bgcolor="#999999"> <p align="center"><strong><font color="#ffffff"> Synonyms & Properties</font></strong></p> </td> <td bgcolor="#999999"> <p align="center"><strong><font color="#ffffff"> Leukocyte expression </font></strong></p> </td> <td bgcolor="#999999"> <p align="center"><strong><font color="#ffffff"> Function</font></strong></p> </td> </tr> <tr> <td><strong> CD1a, b, c, d, e</strong></td> <td> 43-49</td> <td> MHC class I-like structure</td> <td> Dendritic cells, B cells, Langerhans cells, some thymocytes</td> <td> Display of non-peptide and glycolipid antigens for T-cell responses</td> </tr> <tr> <td bgcolor="#cccccc"><strong> CD2</strong></td> <td bgcolor="#cccccc"> 45-58</td> <td bgcolor="#cccccc"> LFA-2, T11, E-rosette receptor; CD58 binding adhesion molecule</td> <td bgcolor="#cccccc"> T cells, thymocytes, NK cells</td> <td bgcolor="#cccccc"> Adhesion molecule involved in T-cell activation</td> </tr> <tr> <td><strong> CD3</strong></td> <td>γ;25-28<br /> δ; 20<br /> ε; 20 </td> <td> T3; composed of 3 polypeptide chains: γ, δ, ε</td> <td> Thmocytes, T cells, NK1-T cells</td> <td> Essential role in TCR signal transduction and in cell-surface expression of the TCR</td> </tr> <tr> <td bgcolor="#cccccc"><strong> CD4</strong></td> <td bgcolor="#cccccc"> 55</td> <td bgcolor="#cccccc"> L3T4</td> <td bgcolor="#cccccc"> MHC class Ⅱ-restricted T cells, some thymocytes, monocytes/macrophage, granulocytes </td> <td bgcolor="#cccccc"> Co-receptor for MHC class Ⅱ-restricted T-cell activation; thymic differentiation marker for T cells; receptor for HIV</td> </tr> <tr> <td><strong> CD5</strong> </td> <td> 58 </td> <td> Leu1, T1, Ly-1</td> <td> Mature T cells, early thymocytes; small amounts on a subset of mature B cells (B1a B cells) </td> <td> Positive or negative modulation of TCR and BCR signaling, depending on the type and developmental stage of cell displaying it</td> </tr> <tr> <td bgcolor="#cccccc"><strong> CD6</strong></td> <td bgcolor="#cccccc"> 105 or 130 </td> <td bgcolor="#cccccc"> T12 </td> <td bgcolor="#cccccc"> Most peripheral T cells, thumocytes, a subset of B cells </td> <td bgcolor="#cccccc"> Adhesion molecule that binds developing thymocytes to thymic epitheral cells; possible co-stimulatory molecule for mature T cells </td> </tr> <tr> <td><strong> CD7</strong></td> <td> 40</td> <td> gp-40 </td> <td> Pluripotent hematopoetic cells, T cells, thymocytes </td> <td> Not known </td> </tr> <tr> <td bgcolor="#cccccc"><strong> CD8</strong></td> <td bgcolor="#cccccc"> </td> <td bgcolor="#cccccc"> T8, Leu-22 ; a membrane-bound dimer of two chains; αβ heterodimer or αα homodimer</td> <td bgcolor="#cccccc"> MHC class Ⅰ-restricted T cells, some thymocytes</td> <td bgcolor="#cccccc"> Coreceptor for MHC class Ⅰ-restricted T cells </td> </tr> <tr> <td><strong> CD9</strong></td> <td> 24 </td> <td> MRP-1, p24 </td> <td> Platelets, early B cells, activated B cells, activated T cells, eosinophils, basophils </td> <td> Modulation of cell adhesion and migration; trigger of platelet activation </td> </tr> <tr> <td bgcolor="#cccccc"><strong> CD10</strong></td> <td bgcolor="#cccccc"> 100 </td> <td bgcolor="#cccccc"> Common acute lymphoblastic leukemia antigen (CALLA), EC 3.4.24.11 (neprilysin), enkephalinase, gp100, neutral endopeptidase (NEP), metalloendopeptidase </td> <td bgcolor="#cccccc"> B-cell precursors, T-cell precursors, bone-marrow stromalcells </td> <td bgcolor="#cccccc"> Protease</td> </tr> <tr> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> </tbody></table></p>
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