Difference between revisions of "Ahr signal Transduction Pathway"
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| − | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif</a> | + | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif</a><br /><br />Ah receptor, bHLH/PAS transcription factor는 transcription factor인 ARNT와 함께 핵에서 heterodimerizes인 2,3,7,8-tetracholrodibenzo-p-dioxin 형태로 운반되는 길항근의 결합 형태이다.<br />Ah receptor/ARNT heterodimer는 dioxin-responsive elements와 결합하고, 유전자를 포함하는 여러개의 발현을 억제한다.<br /><br />Pathway Interaction<br /> |
| + | <table style="WIDTH: 524px; HEIGHT: 143px" cellspacing="1" cellpadding="1" width="524" summary="" border="1"> | ||
| + | <tbody> | ||
| + | <tr> | ||
| + | <td> </td> | ||
| + | <td> </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">AHR</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">HSP90</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">XAP2</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">ARNT</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">HSP90</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Ligand(TCDD)</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">AHR</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">XAP2</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | </tbody> | ||
| + | </table> | ||
Latest revision as of 09:45, 18 August 2006
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif
Ah receptor, bHLH/PAS transcription factor는 transcription factor인 ARNT와 함께 핵에서 heterodimerizes인 2,3,7,8-tetracholrodibenzo-p-dioxin 형태로 운반되는 길항근의 결합 형태이다.
Ah receptor/ARNT heterodimer는 dioxin-responsive elements와 결합하고, 유전자를 포함하는 여러개의 발현을 억제한다.
Pathway Interaction
|
AHR |
HSP90 |
|
|
XAP2 |
|
|
ARNT |
|
HSP90 |
Ligand(TCDD) |
|
|
AHR |
|
|
XAP2 |
