Difference between revisions of "Activation of Src by protein tyrosine phosphatase alpha"

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<a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_srcRPTPPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_srcRPTPPathway.gif</a>
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<a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_srcRPTPPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_srcRPTPPathway.gif</a><br /><br />Cell cycle을 통한 progression은 proto-ancogene C-Src의 활성화에 의해서 수행되는 protein tyrosine kinase이다.<br />Src의 overexproession은 multiple protein substrates의 tyrosine phosphorylation과 세포의 transformation을 가지고 온다.<br /><br />Pathway Interaction<br />
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<table style="WIDTH: 486px; HEIGHT: 163px" cellspacing="1" cellpadding="1" width="486" summary="" border="1">
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    <tbody>
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        <tr>
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            <td>&nbsp;</td>
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            <td>&nbsp;</td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">CDC2</p>
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            </td>
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            <td>
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            <p align="center">Cyclin B</p>
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            </td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">&nbsp;</p>
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            </td>
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            <td>
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            <p align="center">SRC</p>
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            </td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">GRB2</p>
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            </td>
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            <td>
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            <p align="center">RPTPa</p>
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            </td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">PKC</p>
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            </td>
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            <td>
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            <p align="center">RPTPa</p>
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            </td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">CSK</p>
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            </td>
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            <td>
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            <p align="center">SRC</p>
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            </td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">SRC</p>
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            </td>
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            <td>
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            <p align="center">RPTPa</p>
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            </td>
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        </tr>
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        <tr>
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            <td>
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            <p align="center">&nbsp;</p>
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            </td>
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            <td>
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            <p align="center">CSK</p>
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            </td>
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        </tr>
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    </tbody>
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</table>

Latest revision as of 22:03, 17 August 2006

http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_srcRPTPPathway.gif

Cell cycle을 통한 progression은 proto-ancogene C-Src의 활성화에 의해서 수행되는 protein tyrosine kinase이다.
Src의 overexproession은 multiple protein substrates의 tyrosine phosphorylation과 세포의 transformation을 가지고 온다.

Pathway Interaction

   

CDC2

Cyclin B

 

SRC

GRB2

RPTPa

PKC

RPTPa

CSK

SRC

SRC

RPTPa

 

CSK
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