Difference between revisions of "Nature Stem cell"
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<h2 class="insight" minmax_bound="true">Insight: Stem Cells</h2> | <h2 class="insight" minmax_bound="true">Insight: Stem Cells</h2> | ||
| − | <p class="volume" minmax_bound="true"><abbr title="volume" minmax_bound="true"> | + | <p class="volume" minmax_bound="true"><abbr title="volume" minmax_bound="true">lVol. 441, <abbr title="Number" minmax_bound="true">No. 7097 <abbr title="pages" minmax_bound="true">p1059-1102<br /><a href="http://www.nature.com/nature/supplements/insights/stem_cells/images/cover.jpg">http://www.nature.com/nature/supplements/insights/stem_cells/images/cover.jpg</a><br />In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. </abbr>p1059-1102In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. </abbr>No. 7097 p1059-1102In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. </abbr>lVol. 441, No. 7097 p1059-1102In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. p1059-1102In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. No. 7097 p1059-1102In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. lVol. 441, No. 7097 p1059-1102In recent years, stem cells have been the subject of considerable excitement. Great progress has been made in understanding their mechanisms and unravelling their potential for therapeutic application. Widespread use of stem-cell-based therapies is still a long way off, but could one day benefit vast numbers of patients, including those with cancer, neurodegenerative disorders and heart disease. </p> |
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<p class="norm" minmax_bound="true">This <span class="journalname" minmax_bound="true">Nature</span> Insight is accompanied by a special stem cells <a minmax_bound="true" href="http://www.nature.com/podcast/stemcells/index.html">podcast</a>, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field. </p> | <p class="norm" minmax_bound="true">This <span class="journalname" minmax_bound="true">Nature</span> Insight is accompanied by a special stem cells <a minmax_bound="true" href="http://www.nature.com/podcast/stemcells/index.html">podcast</a>, which features interviews with leading stem-cell researchers and a live discussion on the various scientific and ethical problems in this exciting field. </p> | ||
<p class="norm" minmax_bound="true">Readers are invited to join an <a minmax_bound="true" href="http://blogs.nature.com/nature/insightstemcells/">web forum</a> to exchange views and opinions raised by the <span class="journalname" minmax_bound="true">Insight</span> articles. There is also a <a minmax_bound="true" href="http://blogs.nature.com/news/blog/podcasts/">podcast forum</a> for issues discussed in the stem cells podcast. </p> | <p class="norm" minmax_bound="true">Readers are invited to join an <a minmax_bound="true" href="http://blogs.nature.com/nature/insightstemcells/">web forum</a> to exchange views and opinions raised by the <span class="journalname" minmax_bound="true">Insight</span> articles. There is also a <a minmax_bound="true" href="http://blogs.nature.com/news/blog/podcasts/">podcast forum</a> for issues discussed in the stem cells podcast. </p> | ||
| − | <div class="issue-links clearfix" minmax_bound="true"> | + | <div class="issue-links clearfix" minmax_bound="true"></div> |
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<h3 minmax_bound="true">In this supplement</h3> | <h3 minmax_bound="true">In this supplement</h3> | ||
<ul class="anchor" minmax_bound="true"> | <ul class="anchor" minmax_bound="true"> | ||
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem-cell Biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem-cell Biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Natalie DeWitt</p> | <p class="abs" minmax_bound="true">Natalie DeWitt</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/4411059a</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/4411059a.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/4411059a.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/4411059a.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/4411059a.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/4411059a.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/4411059a.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (164<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">A glossary for stem-cell biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">A glossary for stem-cell biology</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Austin Smith</p> | <p class="abs" minmax_bound="true">Austin Smith</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04954</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04954.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04954.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04954.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04954.html">Abstract</a> |<a class="fulltext" title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04954.html">Full Text</a> | <a title="A glossary for stem-cell biology" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04954.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (68<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Nuclear reprogramming and pluripotency</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">Nuclear reprogramming and pluripotency</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Konrad Hochedlinger and Rudolf Jaenisch</p> | <p class="abs" minmax_bound="true">Konrad Hochedlinger and Rudolf Jaenisch</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04955</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04955.html">Abstract</a> | <a class="fulltext" title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04955.html">Full Text</a> | <a title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04955.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04955.html">Abstract</a> | <a class="fulltext" title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04955.html">Full Text</a> | <a title="Nuclear reprogramming and pluripotency" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04955.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (644<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Asymmetric and symmetric stem-cell divisions in development and cancer</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">Asymmetric and symmetric stem-cell divisions in development and cancer</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Sean J. Morrison and Judith Kimble</p> | <p class="abs" minmax_bound="true">Sean J. Morrison and Judith Kimble</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04956</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04956.html">Abstract</a> | <a class="fulltext" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04956.html">Full Text</a> | <a title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04956.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04956.html">Abstract</a> | <a class="fulltext" title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04956.html">Full Text</a> | <a title="Asymmetric and symmetric stem-cell divisions in development and cancer" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04956.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (473<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
<div class="hr" minmax_bound="true"><!-- --></div> | <div class="hr" minmax_bound="true"><!-- --></div> | ||
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">The stem-cell niche as an entity of action</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">The stem-cell niche as an entity of action</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">David T. Scadden</p> | <p class="abs" minmax_bound="true">David T. Scadden</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04957</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04957.html">Abstract</a> | <a class="fulltext" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04957.html">Full Text</a> | <a title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04957.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04957.html">Abstract</a> | <a class="fulltext" title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04957.html">Full Text</a> | <a title="The stem-cell niche as an entity of action" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04957.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (323 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
<div class="hr" minmax_bound="true"><!-- --></div> | <div class="hr" minmax_bound="true"><!-- --></div> | ||
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells, ageing and the quest for immortality</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells, ageing and the quest for immortality</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Thomas A. Rando</p> | <p class="abs" minmax_bound="true">Thomas A. Rando</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04958</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04958.html">Abstract</a> | <a class="fulltext" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04958.html">Full Text</a> | <a title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04958.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04958.html">Abstract</a> | <a class="fulltext" title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04958.html">Full Text</a> | <a title="Stem cells, ageing and the quest for immortality" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04958.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (641 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
<div class="hr" minmax_bound="true"><!-- --></div> | <div class="hr" minmax_bound="true"><!-- --></div> | ||
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Generation of neuronal variability and complexity</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">Generation of neuronal variability and complexity</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Alysson R. Muotri and Fred H. Gage</p> | <p class="abs" minmax_bound="true">Alysson R. Muotri and Fred H. Gage</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04959</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04959.html">Abstract</a> | <a class="fulltext" title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04959.html">Full Text</a> | <a title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04959.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04959.html">Abstract</a> | <a class="fulltext" title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04959.html">Full Text</a> | <a title="Generation of neuronal variability and complexity" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04959.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (756 <abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
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<h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells for the treatment of neurological disorders</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | <h4 minmax_bound="true"><span class="atl" minmax_bound="true">Stem cells for the treatment of neurological disorders</span><span class="free-access" minmax_bound="true"> Free access</span></h4> | ||
<p class="abs" minmax_bound="true">Olle Lindvall and Zaal Kokaia</p> | <p class="abs" minmax_bound="true">Olle Lindvall and Zaal Kokaia</p> | ||
| − | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr> | + | <p class="doi" minmax_bound="true"><abbr title="digital object identifier" minmax_bound="true">doi</abbr>doidoidoi:10.1038/nature04960</p> |
| − | <p class="links" minmax_bound="true"><a class="abstract" title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04960.html">Abstract</a> | <a class="fulltext" title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04960.html">Full Text</a> | <a title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04960.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr> | + | <p class="links" minmax_bound="true"><a class="abstract" title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/abs/nature04960.html">Abstract</a> | <a class="fulltext" title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/full/nature04960.html">Full Text</a> | <a title="Stem cells for the treatment of neurological disorders" minmax_bound="true" href="http://www.nature.com/nature/journal/v441/n7097/pdf/nature04960.pdf"><abbr title="portable document format" minmax_bound="true">PDF</abbr>PDFPDFPDF (402<abbr title="kilobytes" minmax_bound="true">KB</abbr>KBKBKB)</a></p> |
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<p class="abs" minmax_bound="true">Deepak Srivastava and Kathryn N. Ivey</p> | <p class="abs" minmax_bound="true">Deepak Srivastava and Kathryn N. Ivey</p> | ||
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<p class="abs" minmax_bound="true">Claudio Bordignon</p> | <p class="abs" minmax_bound="true">Claudio Bordignon</p> | ||
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