Difference between revisions of "Homoplasmy"
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| − | <p><font color="#000000"><strong>Homoplasmy</strong> is the presence of a </font><font color="#000000">mutation</font><font color="#000000"> affecting all of the </font><font color="#000000">mitochondrial DNA</font><font color="#000000"> (mtDNA) copies in a cell. Since there are hundreds or even thousands of mtDNA copies in every </font><font color="#000000">eukaryotic</font><font color="#000000"> cell, mutations may either be present in all copies (homoplasmy) or affect only a fraction of them (</font><font color="#000000">heteroplasmy</font><font color="#000000">).</font></p> | + | <p><font color="#000000"><strong>Homoplasmy</strong> is the presence of a </font><font color="#000000">mutation</font><font color="#000000"> affecting all of the </font><font color="#000000">mitochondrial DNA</font><font color="#000000"> (mtDNA) copies<strong> in a cell</strong>. Since there are hundreds or even thousands of mtDNA copies in every </font><font color="#000000">eukaryotic</font><font color="#000000"> cell, mutations may either be present in all copies (homoplasmy) or affect only a fraction of them (</font><font color="#000000">heteroplasmy</font><font color="#000000">).</font></p> |
<p><font color="#000000">See also </font><font color="#000000">microheteroplasmy</font><font color="#000000">.</font></p> | <p><font color="#000000">See also </font><font color="#000000">microheteroplasmy</font><font color="#000000">.</font></p> | ||
<p><font color="#000000"><strong>Homeoplasmy</strong> = a state in which all the mitochondria of a cell or a tissue have the same genome, which may be either the wild type genome or a mutated one.</font></p> | <p><font color="#000000"><strong>Homeoplasmy</strong> = a state in which all the mitochondria of a cell or a tissue have the same genome, which may be either the wild type genome or a mutated one.</font></p> | ||
Latest revision as of 07:21, 21 January 2009
Homoplasmy is the presence of a mutation affecting all of the mitochondrial DNA (mtDNA) copies in a cell. Since there are hundreds or even thousands of mtDNA copies in every eukaryotic cell, mutations may either be present in all copies (homoplasmy) or affect only a fraction of them (heteroplasmy).
See also microheteroplasmy.
Homeoplasmy = a state in which all the mitochondria of a cell or a tissue have the same genome, which may be either the wild type genome or a mutated one.
Homoplasmy may also refer to the presence of mutation, or insertion of a foreign gene, into all of the plant plastid organelles DNA e.g. all of the chloroplasts
