CD76-90

CD antigen	MW.(kDa)	Synonyms & Properties	Leukocyte expression	Function
CDw76		Carbohydrate antigen	B cells, subpopulation of T cells	Not known
CD77		Pk blood group antigen, Burkitt's lymphoma antigen, (BLA), ceramide trihexoside (CTH), globotriaosylceramide (Gb3); sphingolipid antigen	Germinal-center B cells	Not known
CD79a	40-45	Ig-α, MB1	B cells	Component of B-cell antigen receptor analogous to CD3, required for cell-surface expression and signal transduction
CD79b	37	B29, Ig-β	B cells	Component of B-cell antigen receptor analogous to CE3, required for cell-surface expression and signal transduction
CD80	60	B7, B7.1, BB1	Activated B and T cells; macrophages	Co-stimulation of T-cell activation with CD86
CD81	26	Target for anti-proliferative antigen-1 (TAPA-1)	Broadly expressed on hematopoeitic cells; expressed by endothelial and epithelial cells; absent from erythrocytes, platelets, and neutrophils	Member of CD19/CD21/Leu-13 signal-transduction complex, the B-cell co-receptor
CD82	45-90	4F9, C33, IA4, KAI1, R2	Activated/differentiated hematopoeitic cells	Signal transduction: may induce T-cell spreading and pseudopod formation, modulate T-cell proliferation, and provide co-stimulatory signals for cytokine production; possible role in activation of monocytes
CD83	43	HB15	Dendritic cells, B cells, Langerhans cells	Not known
CD84	73	GR6	Monocytes, platelets, circulating B cells	Not known
CD85	110	GR4	Plasma cells, mantle-zone and germinal-center B cells, subpopulation of peripheral-blood NK cells	Possible role in T-cell activation in peripheral blood
CD86	80	B7.2	Dendritic cells, memory B cells, germinal-center B cells, monocytes	Major T cell costimulatory molecule, interacting with CD28 (stimulatory) and CTLA4 (inhibitory)
CD87	41-68, 35-39	Urokinase plasminogen activator receptor (uPAR)	T cells, NK cells, monocytes, neutrophils; non-hematopoeitic cells such as vascular endothelial cells, fibroblasts, smooth muscle cells, keratinocytes, placental trophoblasts, hepatocytes	Receptor for uPA, which can convert plasminogen to plasmin; possible role in β2 integrin-dependent adherence and chemotaxis
CD88	43	C5a receptor, C5aR	Granulocytes, monocytes, dendritic cells	C5a-mediated inflammation; activation of granulocytes
CD89	45-70, 55-75, 70-100, 50-65	Fcα-receptor R (Fcα-R), IgA Fc receptor, IgA receptor	Myeloid-lineage cells from promyelocytes to neutrophils and from promonocyte to monocytes; activated eosinophils, alveolar and splenic macrophages	Induction of phagocytosis, degranulation, respiratory burst, killing of microorganisms
CD90	25-35	Thy-1	Hematopoeitic stem cells, thymocytes, peripheral T cells, human node HEV endothelium	Possible involvement in lymphocyte co-stimulation; possible inhibition of proliferation and differentiation of hematopoeitic stem cells