Changes

<td>&nbsp;subunit Subunit of low-affinity Fc receptor, involved in phagocytosis of antibody-complexed antien and in antibody-dependent cell-mediated cytotosicity (ADCC)</td>

<td>&nbsp;95</td> <td>&nbsp;T3&beta; composed of 3 polypeptide chains:2&nbsp;integrin chain;&gammanbsp;, &deltanbsp;, &epsilonbeta;subunit that combines with CD11a, CD11b, or CD11c subunit to form integrins</td> <td>&nbsp;Thmocytes, T cells, NK1-T cellsAll leukocytes&nbsp;</td> <td>&nbsp;Essential role in TCR signal transduction Adhesion and signaling in cell-surface expression of the TCRhematopoietic system (see entries for CD11a, CD11b, and CD11c)&nbsp;</td>

<td bgcolor="#cccccc">&nbsp;&gt;120</td> <td bgcolor="#cccccc">&nbsp;L3T4B4&nbsp;</td> <td bgcolor="#cccccc">&nbsp;MHC classFollicular dendritic cells, B cells from earliest recognizable B-lineage cells during development to B-cell blasts but lost on maturation to plasma cells&nbsp;Ⅱ-restricted T cells, some thymocytes, monocytes/macrophage, granulocytes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;CoPart of B-receptor for MHC class&nbspcell coreceptor with CD21 and CD81;Ⅱ-restricted Ta critical signal transduction molecule that regulates B-cell development, activation; thymic , and differentiation marker for T cells; receptor for HIV</td>

<td>&nbsp;33</td> <td>&nbsp;Leu1B1, T1, Ly-1Bp35&nbsp;</td> <td>&nbsp;Mature T cells, early thymocytes; small amounts on a subset of mature B cells (B1a B cells)&nbsp;</td> <td>&nbsp;Positive or negative modulation of TCR and BCR signaling, depending on the type and developmental stage of cell displaying itNot known&nbsp;</td>

<td bgcolor="#cccccc">&nbsp;145 (membrane form)<br /> 130 (soluble form)</td> <td bgcolor="#cccccc">&nbsp;T12C3d receptor, CR2, Epstein Barr virus receptor (EBV-R)&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Most peripheral T B cells, thumocytesfollicular dendritic cells,&nbsp;a subset of B cellsimmature thymocytes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Adhesion molecule that binds developing thymocytes to thymic epitheral cellsReceptor for EBV, C3d, C3dg, and iC3b; with CD19 and CD81, part of the B-cell coreceptor, a large&nbsp; possible cosignal-stimulatory molecule for mature T cellstransduction complex&nbsp;</td>

<td>&nbsp;140</td> <td>&nbsp;gpBL-40&nbsp;CAM, Lyb8 in mouse</td> <td>&nbsp;Pluripotent hematopoetic Surface of mature B cells, T cytoplasm of late pro-and early pre-B cells, thymocytes&nbsp;</td> <td>&nbsp;Not knownAdhesion molecule; signaling molecule&nbsp;</td>

<td bgcolor="#cccccc">&nbsp;45</td> <td bgcolor="#cccccc">&nbsp;T8B6, LeuBLAST-22 2, Fc&epsilon; a membraneRⅡ, Leu-bound dimer of two chains20 ;&nbsp;&alpha;&beta; heterodimer or &alpha;&alpha;low-affinity IgE receptor&nbsp;homodimer</td> <td bgcolor="#cccccc">&nbsp;MHC classHuman B cells, monocytes follicular dendritic cells&nbsp;Ⅰ-restricted T cells, some thymocytes</td> <td bgcolor="#cccccc">&nbsp;Coreceptor for MHC class&nbspRegulation of IgE synthesis;Ⅰtrigger to release TNF, IL-1, IL-restricted T cells6, and GM-CSF from human monocytes&nbsp;</td>

<td>&nbsp;35-45</td> <td>&nbsp;MRPBA-1, p24heat-stable antigen (HSA) in mouse&nbsp;</td> <td>&nbsp;Platelets, early B cells-cell lineage but lost at plasma-cell stage, activated B cells, activated T cells, eosinophils, basophilsmature granulocytes&nbsp;</td> <td>&nbsp;Modulation of cell adhesion and migration; trigger of platelet activationNot known&nbsp;</td>

<td bgcolor="#cccccc">&nbsp;55</td> <td bgcolor="#cccccc">&nbsp;Common acute lymphoblastic leukemia antigen (CALLA)IL-2 receptor&nbsp;&alpha; chain, EC 3.4.24.11 (neprilysin)IL-2R, enkephalinase, gp100, neutral endopeptidase (NEP), metalloendopeptidaseTac antogen&nbsp;</td> <td bgcolor="#cccccc">&nbsp;BPHA-cell precursors, stimulated Tcells; anti-IGM-cell precursorsstimulated B cells, boneLPS-marrow stromalcellsstimulated monocytes/macrophages&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Protease&alpha; subunit of receptor for cytokine IL-2&nbsp;</td>

<td>&nbsp;110, 120</td> <td>&nbsp;&alpha;-L integrin chainEC 3.4.14.5, LFAadenosine deaminase-1 &alpha; binding protein (leukocyte functionADA-associated molecule-1 binding protein), dipeptidylpeptidase Ⅳ (DPV Ⅳ ectoenzyme)&alpha;) chainnbsp; forms LFA-1 by association with CD18</td> <td>&nbsp;MonocytesMature of activated T cells, B cells,acrophagesNK cells, granulocytes, lymphocytes&nbsp;macrophages</td> <td>&nbsp;Subunit of LFACo-1. a membrane glycoprotein that provides cellstimulatory molecule in T-cell adhesion by interaction with ICAM-1 (intercellular adhesion molecule-1)&nbsp;activation&nbsp;</td>

<td bgcolor="#cccccc"><strong>&nbsp;CD11bCD27</strong></td> <td bgcolor="#cccccc">&nbsp;55</td> <td bgcolor="#cccccc">&nbsp;C3biRSI52, CR3; T14&alpha; chain of MAC-1 integrinnbsp; forms MAC-1 by association with CD18</td> <td bgcolor="#cccccc">&nbsp;GranulocytesMature thymocytes, monocytesactivated T cells and B cells, NK cells, subset of macrophages, most peropheral T cells, subsets of memory-type B cells&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Subunit Mediation of MACa co-1, which mediates&nbsp;interactions og neutrophils and monocytes with stimulated endothelium, phagocytosis of particles coated with iC3b or IgG, spreading or chemotaxis of leukocytes; ligand-binding molecule that binds C3b, ICAMstimulatory signal for T-1 (CD54), ICAM-2 (CD102), and fibrinogen</td> </tr> <tr> <td><strong>&nbsp;CD27</strong></td> <td>&nbsp;</td> <td>&nbsp;&alpha;B-X integrin chain,&nbsp;&nbspcell activation;&alpha;x&beta;2, &alpha; chain of integrin CR4, leukocte surface antigen, p150, 95 ; forms CR by association with CD18</td> <td>&nbsp;Monocytes, macrophage, NK cells, granulocytes, subset of role in murine T -cell, subset of B cells&nbsp;</td> <td>development&nbsp;Subunit of complex with CD18 that is similar to CD 11b/CD18 complex, with which it acts cooperatively; the major form of CD11/CD18 on tissue macrophage</td>

<td bgcolor="#cccccc"><strong>&nbsp;CD28</strong></td> <td bgcolor="#cccccc">&nbsp;90 (homodimeric form)</td> <td bgcolor="#cccccc">&nbsp;T44, Tp44&nbsp;</td> <td bgcolor="#cccccc">&nbsp;MonocytesMatur CD3+ thymocytes, granulocytesmost peripheral T cells, plateletsplasma cells&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Not knownCo-stimulation of T-cell proliferation and cytokine production upon binding CD80 or CD86&nbsp;</td>

<tdbgcolor="#cccccc"><strong>&nbsp;CD29</strong></td> <tdbgcolor="#cccccc">&nbsp;130</td> <tdbgcolor="#cccccc">&nbsp;Aminopeptidase N (APN)&beta;1 integrin chain, GP, EC 3.4.11.2platelet GPⅡa, gp150VLA-&beta; chain&nbsp;</td> <tdbgcolor="#cccccc">&nbsp;Early progenitors of granulocytes and monocytes (CFU-GM), mature granulocytes and monocytes, bone-marrow stromal cells, osteoclasts, a small number of lasrge granular lymphocytesLeukocytes&nbsp;</td> <tdbgcolor="#cccccc">&nbsp;Not known&beta; subunit of VLA-1 integrin&nbsp;</td>

<td bgcolor="#cccccc"><strong>&nbsp;<strong>CD30</strong></td> <td bgcolor="#cccccc">&nbsp;120</td> <td bgcolor="#cccccc">&nbsp;LPS receptor (LPSBer-R)H2 antigen, Ki-1 antigen&nbsp;</td> <td bgcolor="#cccccc">&nbsp;MonocytesActivated T cells, macrophagesactivated B cells, granulocytes (weak expression)activated NK cells, monocytes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Receptor for endotoxin (lipopolysaccharide [LPS])Stimulation of proliferation or induction of cell death, activating monocytes or neutrophils to release cytokines (TNF) depending upon conditions and up-regulate adhesion molecules when LPS is boundcell type expressing it&nbsp;</td>