Difference between revisions of "CD16-30"

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             <td><strong>&nbsp;CD18</strong></td>
 
             <td><strong>&nbsp;CD18</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;T3; composed of 3 polypeptide chains:&nbsp;&gamma;, &delta;, &epsilon;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Thmocytes, T cells, NK1-T cells</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Essential role in TCR signal transduction and in cell-surface expression of the TCR</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD19</strong></td>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD19</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;L3T4</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;MHC class&nbsp;Ⅱ-restricted T cells, some thymocytes, monocytes/macrophage, granulocytes&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Co-receptor for MHC class&nbsp;Ⅱ-restricted T-cell activation; thymic differentiation marker for T cells; receptor for HIV</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td><strong>&nbsp;CD20</strong></td>
 
             <td><strong>&nbsp;CD20</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;Leu1, T1, Ly-1</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Mature T cells, early thymocytes; small amounts on a subset of mature B cells (B1a B cells)&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Positive or negative modulation of TCR and BCR signaling, depending on the type and developmental stage of cell displaying it</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD21</strong></td>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD21</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;T12&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Most peripheral T cells, thumocytes,&nbsp;a subset of B cells&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Adhesion molecule that binds developing thymocytes to thymic epitheral cells; possible co-stimulatory molecule for mature T cells&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td><strong>&nbsp;CD22</strong></td>
 
             <td><strong>&nbsp;CD22</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;gp-40&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Pluripotent hematopoetic cells, T cells, thymocytes&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Not known&nbsp;</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD23</strong></td>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD23</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;T8, Leu-22 ; a membrane-bound dimer of two chains;&nbsp;&alpha;&beta; heterodimer or &alpha;&alpha;&nbsp;homodimer</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;MHC class&nbsp;Ⅰ-restricted T cells, some thymocytes</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Coreceptor for MHC class&nbsp;Ⅰ-restricted T cells&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td><strong>&nbsp;CD24</strong></td>
 
             <td><strong>&nbsp;CD24</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;MRP-1, p24&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Platelets, early B cells, activated B cells, activated T cells, eosinophils, basophils&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Modulation of cell adhesion and migration; trigger of platelet activation&nbsp;</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD25</strong></td>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD25</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Common acute lymphoblastic leukemia antigen (CALLA), EC 3.4.24.11 (neprilysin), enkephalinase, gp100, neutral endopeptidase (NEP), metalloendopeptidase&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;B-cell precursors, T-cell precursors, bone-marrow stromalcells&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Protease</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td><strong>&nbsp;CD26</strong></td>
 
             <td><strong>&nbsp;CD26</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;&alpha;-L integrin chain, LFA-1 &alpha; (leukocyte function-associated molecule-1 &alpha;) chain; forms LFA-1 by association with CD18</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Monocytes, ,acrophages, granulocytes, lymphocytes&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Subunit of LFA-1. a membrane glycoprotein that provides cell-cell adhesion by interaction with ICAM-1 (intercellular adhesion molecule-1)&nbsp;&nbsp;</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD11b</strong></td>
 
             <td bgcolor="#cccccc"><strong>&nbsp;CD11b</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;C3biR, CR3; &alpha; chain of MAC-1 integrin; forms MAC-1 by association with CD18</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Granulocytes, monocytes, NK cells, subset of T cells, subsets of B cells&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Subunit of MAC-1, which mediates&nbsp;interactions og neutrophils and monocytes with stimulated endothelium, phagocytosis of particles coated with iC3b or IgG, spreading or chemotaxis of leukocytes; ligand-binding molecule that binds C3b, ICAM-1 (CD54), ICAM-2 (CD102), and fibrinogen</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td><strong>&nbsp;CD27</strong></td>
 
             <td><strong>&nbsp;CD27</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;&alpha;-X integrin chain,&nbsp;&nbsp;&alpha;x&beta;2, &alpha; chain of integrin CR4, leukocte surface antigen, p150, 95 ; forms CR by association with CD18</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Monocytes, macrophage, NK cells, granulocytes, subset of T cell, subset of B cells&nbsp;</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Subunit of complex with CD18 that is similar to CD 11b/CD18 complex, with which it acts cooperatively; the major form of CD11/CD18 on tissue macrophage</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
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             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Monocytes, granulocytes, platelets</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Not known</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td><strong>&nbsp;CD29</strong></td>
 
             <td><strong>&nbsp;CD29</strong></td>
 
             <td>&nbsp;</td>
 
             <td>&nbsp;</td>
−
             <td>&nbsp;Aminopeptidase N (APN), EC 3.4.11.2, gp150</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Early progenitors of granulocytes and monocytes (CFU-GM), mature granulocytes and monocytes, bone-marrow stromal cells, osteoclasts, a small number of lasrge granular lymphocytes</td>
+
             <td>&nbsp;</td>
−
             <td>&nbsp;Not known</td>
+
             <td>&nbsp;</td>
 
         </tr>
 
         </tr>
 
         <tr>
 
         <tr>
 
             <td bgcolor="#cccccc">&nbsp;<strong>CD30</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;<strong>CD30</strong></td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
 
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;LPS receptor (LPS-R)</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Monocytes, macrophages, granulocytes (weak expression)</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
−
             <td bgcolor="#cccccc">&nbsp;Receptor for endotoxin (lipopolysaccharide [LPS]), activating monocytes or neutrophils to release cytokines (TNF) and up-regulate adhesion molecules when LPS is bound&nbsp;</td>
+
             <td bgcolor="#cccccc">&nbsp;</td>
 
         </tr>
 
         </tr>
 
     </tbody>
 
     </tbody>
 
</table>
 
</table>

Revision as of 16:21, 4 September 2006

 CD antigen

 MW.(kDa) 

 Synonyms & Properties

 Leukocyte expression  

 Function
 CD16  50-80  FCγRⅢA  Macrophage, NK cells, neutrophils  Subunit of low-affinity Fc receptor, involved in phagocytosis of antibody-complexed antien and in antibody-dependent cell-mediated cytotosicity (ADCC)
 CDw17    Lactosylceramide (LacCer); carbohydrate antigen  Monocytes, granulocytes, basophils, platelets, subset of peripheral B cells (CD19+), tonsillar dendritic cells  Not known; ability to bind bacteria for possible role in phagocytosis
 CD18        
 CD19         
 CD20        
 CD21        
 CD22        
 CD23        
 CD24        
 CD25        
 CD26        
 CD11b        
 CD27        
 CD28        
 CD29        
 CD30        
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