Changes

<a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_acrPathway.gif</a><br /><br />Ah receptor, bHLH/PAS transcription factor는 transcription factor인 ARNT와 함께 핵에서 heterodimerizes인 2,3,7,8-tetracholrodibenzo-p-dioxin 형태로 운반되는 길항근의 결합 형태이다.<br />Ah receptor/ARNT heterodimer는 dioxin-responsive elements와 결합하고, 유전자를 포함하는 여러개의 발현을 억제한다.<br /><br />Pathway Interaction<br /><table style="WIDTH: 524px; HEIGHT: 143px" cellspacing="1" cellpadding="1" width="524" summary="" border="1"> <tbody> <tr> <td>&nbsp;</td> <td>&nbsp;</td> </tr> <tr> <td> <p align="center">AHR</p> </td> <td> <p align="center">HSP90</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">XAP2</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">ARNT</p> </td> </tr> <tr> <td> <p align="center">HSP90</p> </td> <td> <p align="center">Ligand(TCDD)</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">AHR</p> </td> </tr> <tr> <td> <p align="center">&nbsp;</p> </td> <td> <p align="center">XAP2</p> </td> </tr> </tbody></table>