Difference between revisions of "ATM Signaling Pathway"
From Opengenome.net
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− | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_atmPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_atmPathway.gif</a> | + | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_atmPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_atmPathway.gif</a><br /><br />Pathway Interaction<br /> |
+ | <table style="WIDTH: 688px; HEIGHT: 563px" cellspacing="1" cellpadding="1" width="688" summary="" border="1"> | ||
+ | <tbody> | ||
+ | <tr> | ||
+ | <td> </td> | ||
+ | <td> </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">CHK1</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">ATM</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">p53-mdm2</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">CHK2</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">ATM</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">p53</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">p21</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">GADD45</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">mdm2</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">Apoptosis</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">p73</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">C-Ab1</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">Apoptosis</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">ATM</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">CHK2</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">CHK1</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">RPA</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">C-Abl</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">mdm2</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">CTIP</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">NFkB</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">p53</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">NFkB</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">IKBa</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">Apoptosis</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">ATM</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">RAD51</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">CAD1</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">BRCA1</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">BRCA1</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">GADD45</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">Rad51</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">MDM2</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">p53, ATM</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center"> </p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">BRCA1</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> | ||
+ | <p align="center">JUN</p> | ||
+ | </td> | ||
+ | <td> | ||
+ | <p align="center">SAPK1</p> | ||
+ | </td> | ||
+ | </tr> | ||
+ | </tbody> | ||
+ | </table> | ||
+ | <div align="center"> | ||
+ | <table style="WIDTH: 689px; HEIGHT: 43px" cellspacing="1" cellpadding="1" width="689" align="left" summary="" border="1"> | ||
+ | <tbody> | ||
+ | <tr> | ||
+ | <td>RAD50</td> | ||
+ | <td>nibrin</td> | ||
+ | </tr> | ||
+ | <tr> | ||
+ | <td> </td> | ||
+ | <td>Mre11</td> | ||
+ | </tr> | ||
+ | </tbody> | ||
+ | </table> | ||
+ | </div> |
Revision as of 23:54, 17 August 2006
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_atmPathway.gif
Pathway Interaction
CHK1 |
ATM |
|
p53-mdm2 |
CHK2 |
ATM |
p53 |
p21 |
|
GADD45 |
|
mdm2 |
|
Apoptosis |
p73 |
C-Ab1 |
|
Apoptosis |
ATM |
CHK2 |
|
CHK1 |
|
RPA |
|
C-Abl |
|
mdm2 |
|
CTIP |
|
NFkB |
|
p53 |
NFkB |
IKBa |
|
Apoptosis |
|
ATM |
RAD51 |
CAD1 |
|
BRCA1 |
BRCA1 |
GADD45 |
|
Rad51 |
MDM2 |
p53, ATM |
|
BRCA1 |
JUN |
SAPK1 |
RAD50 | nibrin |
Mre11 |