Difference between revisions of "Apoptotic DNA fragmentation and tissue homeostasis"
From Opengenome.net
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| − | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_DNAfragmentPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_DNAfragmentPathway.gif</a> | + | <a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_DNAfragmentPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_DNAfragmentPathway.gif</a><br /><br />Pathway Interaction<br /> |
| + | <table style="WIDTH: 788px; HEIGHT: 579px" cellspacing="1" cellpadding="1" width="788" summary="" border="1"> | ||
| + | <tbody> | ||
| + | <tr> | ||
| + | <td> </td> | ||
| + | <td> </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">BAX</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">BID</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">BCL-2</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">BCL-XL</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">p53</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">BAD</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">AKT pathway</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">AKT</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">BAD</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Pro-CASPASE</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">APAF-1</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Cytochrome C</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">pro-caspase 9</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">BCL2</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">BCL-KL</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">BAX</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">TLN</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">PAXILLIN</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">PKC</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">EIF2a</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">EIF2a</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">STAT1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Capases</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">ATM</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">p53</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP3</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">pro-caspase3</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">caspase6</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CASP7</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">FAK, PKC 등의 Modified signaling</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">CYCS</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">ADAF-1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">Pro-caspase 9</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">STAT1</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">PAXILLIN</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">EIF2a</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">PARP</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center">PARP</p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">CASPASES</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td> | ||
| + | <p align="center"> </p> | ||
| + | </td> | ||
| + | <td> | ||
| + | <p align="center">STAT1</p> | ||
| + | </td> | ||
| + | </tr> | ||
| + | </tbody> | ||
| + | </table> | ||
Revision as of 23:47, 17 August 2006
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_DNAfragmentPathway.gif
Pathway Interaction
|
BAX |
BID |
|
|
BCL-2 |
|
|
BCL-XL |
|
|
p53 |
|
BAD |
AKT pathway |
|
AKT |
BAD |
|
|
Pro-CASPASE |
|
APAF-1 |
Cytochrome C |
|
|
pro-caspase 9 |
|
BCL2 |
BCL-KL |
|
|
BAX |
|
TLN |
PAXILLIN |
|
|
PKC |
|
|
EIF2a |
|
EIF2a |
STAT1 |
|
|
Capases |
|
ATM |
p53 |
|
CASP3 |
pro-caspase3 |
|
|
caspase6 |
|
CASP7 |
FAK, PKC 등의 Modified signaling |
|
CYCS |
ADAF-1 |
|
|
Pro-caspase 9 |
|
STAT1 |
PAXILLIN |
|
|
EIF2a |
|
|
PARP |
|
PARP |
CASPASES |
|
|
STAT1 |
