NCBI

NCBI






# NCBI Database

Database<o:p></o:p>
Pubmed<o:p></o:p>	생물/ 의학 관련 서지정보 데이터베이스<o:p></o:p>
Nucleotide<o:p></o:p>	GenBank, EMBL(European Molecular Biology Laboratory), DDBJ(DNA Database of Japan)을 포함하는 Nucleotide Database<o:p></o:p>
Protein <o:p></o:p>	GenBank, EMBL, 및 DDBJ 등에 등록된 DNA 서열로부터 얻어진 단백질서열을 제공하는 database.
Structure<o:p></o:p>	결정체 연구나 핵자기공명 연구를 통해 얻어진 단백질 구조를 제공. 특히 구조에 대한 data를 기존의 문헌에서 밝혀진 서열 data 등의 정보와 연계시켜 놓은 database.<o:p></o:p>
Genome<o:p></o:p>	다양한 유전체, [[염색체]] [[유전자지도]] 등에 대한 정보를 종합적으로 제공<o:p></o:p>
Population study data sets<o:p></o:p>	인종학, [[계통발생학]], [[돌연변이]] 등에서 발생될 수 있는 배열 문제를 다룸<o:p></o:p>
OMIM <o:p></o:p>	인간의 유전자와 유전자 이상 등에 관한 문헌정보 제공, 유전자 성 레코드, 유전지도, 데이터베이스를 연결할수 있음<o:p></o:p>
Taxonomy<o:p></o:p>	유전학 데이터베이스에서 나타나는 모든 조직체의 분류학 사전 데이터베이스<o:p></o:p>
ProbeSet<o:p></o:p>	유전자 발현 및 핵산혼성화 배열에 유용한 probe에 대한 정보를 제공<o:p></o:p>
3D Domains<o:p></o:p>	NCBI에서 제공하는 단백질의 보존된 영역에 대한 3차구조 자료를 제공.<o:p></o:p>
UNiSTS<o:p></o:p>	여러 data sources에서 얻어진 표지인자 및 유전자지도를 통합하여 단일화 시킨 서열인식부위 정보를 제공<o:p></o:p>
SNP<o:p></o:p>	단일염기다형성 또는 짧은 염기 삭제나 첨가에 의한 다형성에 대한 중심적 정보를 제공<o:p></o:p>

#NCBI Handbook

Part 1. The Databases

1. GenBank: The Nucleotide Sequence Database
Ilene Mizrachi.
Created: October 9, 2002, Updated: July 27, 2004

2. PubMed: The Bibliographic Database
Kathi Canese, Jennifer Jentsch, and Carol Myers.
Created: October 9, 2002, Updated: August 13, 2003

3. Macromolecular Structure Databases
Eric Sayers and Steve Bryant.
Created: October 9, 2002, Updated: August 13, 2003

4. The Taxonomy Project
Scott Federhen.
Created: October 9, 2002, Updated: August 13, 2003

5. The Single Nucleotide Polymorphism Database (dbSNP) of Nucleotide Sequence Variation
Adrienne Kitts and Stephen Sherry.
Created: October 09, 2002, Updated: May 03, 2006

6. The Gene Expression Omnibus (GEO): A Gene Expression and Hybridization Repository
Ron Edgar and Alex Lash.
Created: October 9, 2002, Updated: August 13, 2003

7. Online Mendelian Inheritance in Man (OMIM): A Directory of Human Genes and Genetic Disorders
Donna Maglott, Joanna S. Amberger, and Ada Hamosh.
Created: October 9, 2002

8. The NCBI BookShelf: Searchable Biomedical Books
Bart Trawick, Jeff Beck, and Jo McEntyre.
Created: October 9, 2002, Updated: August 13, 2003

9. PubMed Central (PMC): An Archive for Literature from Life Sciences Journals
Jeff Beck and Ed Sequeira.
Created: October 9, 2002, Updated: August 13, 2003

10. The SKY/CGH Database for Spectral Karyotyping and Comparative Genomic Hybridization Data
Turid Knutsen, Vasuki Gobu, Rodger Knaus, Thomas Ried, and Karl Sirotkin.
Created: October 9, 2002, Updated: August 13, 2003

11. The Major Histocompatibility Complex Database, dbMHC
Adrienne Kitts, Michael Feolo, and Wolfgang Helmberg.
Created: May 27, 2003, Updated: August 13, 2003

Part 2. Data Flow and Processing

12. Sequin: A Sequence Submission and Editing Tool
Jonathan Kans.
Created: October 9, 2002, Updated: August 13, 2003

13. The Processing of Biological Sequence Data at NCBI
Karl Sirotkin, Tatiana Tatusova, Eugene Yaschenko, and Mark Cavanaugh.
Created: October 09, 2002, Updated: March 14, 2006

14. Genome Assembly and Annotation Process
Paul Kitts.
Created: October 9, 2002, Updated: August 13, 2003

Part 3. Querying and Linking the Data

15. The Entrez Search and Retrieval System
Jim Ostell.
Created: October 9, 2002, Updated: August 13, 2003

16. The BLAST Sequence Analysis Tool
Tom Madden.
Created: October 9, 2002, Updated: August 13, 2003

17. LinkOut: Linking to External Resources from Entrez Databases
Kathy Kwan.
Created: October 9, 2002, Updated: August 13, 2003

18. The Reference Sequence (RefSeq) Project
Kim D. Pruitt, Tatiana Tatusova, and James M. Ostell.
Created: October 9, 2002, Updated: August 13, 2003

19. Entrez Gene: A Directory of Genes
Donna Maglott, Kim Pruitt, and Tatiana Tatusova.
Created: March 3, 2005

20. Using the Map Viewer to Explore Genomes
Susan M. Dombrowski and Donna Maglott.
Created: October 9, 2002, Updated: August 13, 2003

21. UniGene: A Unified View of the Transcriptome
Joan U. Pontius, Lukas Wagner, and Gregory D. Schuler.
Created: October 9, 2002, Updated: August 13, 2003

22. The Clusters of Orthologous Groups (COGs) Database: Phylogenetic Classification of Proteins from Complete Genomes
Eugene V. Koonin.
Created: October 9, 2002, Updated: August 13, 2003

Part 4. User Support

23. User Services: Helping You Find Your Way
David Wheeler and Barbara Rapp.
Created: October 9, 2002, Updated: August 13, 2003

24. Exercises: Using Map Viewer
David Wheeler, Kim Pruitt, Donna Maglott, Susan Dombrowski, and Andrei Gabrelian.
Created: November 4, 2002, Updated: August 13, 2003

Glossary
Created: October 9, 2002, Updated: April 30, 2003