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History of Bioinformatics - Revision history
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 07:01, 30 March 2011</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1986: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The SWISS-PROT database is created by the Department of Medical Biochemistry of the University of Geneva and the European Molecular Biology Laboratory (EMBL).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1986: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The SWISS-PROT database is created by the Department of Medical Biochemistry of the University of Geneva and the European Molecular Biology Laboratory (EMBL).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1987: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The use of yeast artifical chromosomes (YAC) is described (David T. Burke, et. al., <em>Science</em>, <strong>236</strong>: 806-812).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1987: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The use of yeast artifical chromosomes (YAC) is described (David T. Burke, et. al., <em>Science</em>, <strong>236</strong>: 806-812).</font></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987: </strong></font><font face="Times New Roman">McClintock, Barbara (1987).</font><em><font face="Times New Roman"> The Discovery and Characterization of Transposable Elements: The Collected <a href="<del class="diffchange diffchange-inline">http</del>://<del class="diffchange diffchange-inline">www.college-paper.org</del>">Custon College Paper</a> of Barbara McClintock</font></em><font face="Times New Roman">. New York: Garland, 1987.&nbsp; In her 1983 Nobel lecture, McClintock said the genome is &quot;a highly sensitive organ of the cell, that in times of stress could initiate its own restructuring and renovation.&quot; See the </font><font face="Times New Roman">biography</font><font face="Times New Roman"> at the Cold Springs Harbor site (external). For a current discussion, see </font><font face="Times New Roman">Pennisi 1998</font><font face="Times New Roman">.&nbsp; </font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987: </strong></font><font face="Times New Roman">McClintock, Barbara (1987).</font><em><font face="Times New Roman"> The Discovery and Characterization of Transposable Elements: The Collected <a href="<ins class="diffchange diffchange-inline">javascript</ins>:<ins class="diffchange diffchange-inline">void(0);</ins>/<ins class="diffchange diffchange-inline">*1242361025806*</ins>/">Custon College Paper</a> of Barbara McClintock</font></em><font face="Times New Roman">. New York: Garland, 1987.&nbsp; In her 1983 Nobel lecture, McClintock said the genome is &quot;a highly sensitive organ of the cell, that in times of stress could initiate its own restructuring and renovation.&quot; See the </font><font face="Times New Roman">biography</font><font face="Times New Roman"> at the Cold Springs Harbor site (external). For a current discussion, see </font><font face="Times New Roman">Pennisi 1998</font><font face="Times New Roman">.&nbsp; </font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The physical map of <em>e. coli</em> is published (Y. Kohara, et. al., <em>Cell</em> <strong>51:</strong> 319-337).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The physical map of <em>e. coli</em> is published (Y. Kohara, et. al., <em>Cell</em> <strong>51:</strong> 319-337).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">Perl (Practical Extraction Report Language) is released by Larry Wall.</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">Perl (Practical Extraction Report Language) is released by Larry Wall.</font></p></div></td></tr>
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http://Opengenome.net/index.php?title=History_of_Bioinformatics&diff=29337&oldid=prev
Mickey at 05:11, 17 May 2009
2009-05-17T05:11:17Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 05:11, 17 May 2009</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1986: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The SWISS-PROT database is created by the Department of Medical Biochemistry of the University of Geneva and the European Molecular Biology Laboratory (EMBL).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1986: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The SWISS-PROT database is created by the Department of Medical Biochemistry of the University of Geneva and the European Molecular Biology Laboratory (EMBL).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1987: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The use of yeast artifical chromosomes (YAC) is described (David T. Burke, et. al., <em>Science</em>, <strong>236</strong>: 806-812).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1987: </strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The use of yeast artifical chromosomes (YAC) is described (David T. Burke, et. al., <em>Science</em>, <strong>236</strong>: 806-812).</font></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987: </strong></font><font face="Times New Roman">McClintock, Barbara (1987).</font><em><font face="Times New Roman"> The Discovery and Characterization of Transposable Elements: The Collected <a href="<del class="diffchange diffchange-inline">javascript</del>:<del class="diffchange diffchange-inline">void(0);</del>/<del class="diffchange diffchange-inline">*1242361025806*</del>/">Custon College Paper</a> of Barbara McClintock</font></em><font face="Times New Roman">. New York: Garland, 1987.&nbsp; In her 1983 Nobel lecture, McClintock said the genome is &quot;a highly sensitive organ of the cell, that in times of stress could initiate its own restructuring and renovation.&quot; See the </font><font face="Times New Roman">biography</font><font face="Times New Roman"> at the Cold Springs Harbor site (external). For a current discussion, see </font><font face="Times New Roman">Pennisi 1998</font><font face="Times New Roman">.&nbsp; </font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987: </strong></font><font face="Times New Roman">McClintock, Barbara (1987).</font><em><font face="Times New Roman"> The Discovery and Characterization of Transposable Elements: The Collected <a href="<ins class="diffchange diffchange-inline">http</ins>://<ins class="diffchange diffchange-inline">www.college-paper.org</ins>">Custon College Paper</a> of Barbara McClintock</font></em><font face="Times New Roman">. New York: Garland, 1987.&nbsp; In her 1983 Nobel lecture, McClintock said the genome is &quot;a highly sensitive organ of the cell, that in times of stress could initiate its own restructuring and renovation.&quot; See the </font><font face="Times New Roman">biography</font><font face="Times New Roman"> at the Cold Springs Harbor site (external). For a current discussion, see </font><font face="Times New Roman">Pennisi 1998</font><font face="Times New Roman">.&nbsp; </font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The physical map of <em>e. coli</em> is published (Y. Kohara, et. al., <em>Cell</em> <strong>51:</strong> 319-337).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The physical map of <em>e. coli</em> is published (Y. Kohara, et. al., <em>Cell</em> <strong>51:</strong> 319-337).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">Perl (Practical Extraction Report Language) is released by Larry Wall.</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1987:</strong></font><font face="Times New Roman" size="3"> </font><font face="Times New Roman,Sans Serif" color="#000000" size="3">Perl (Practical Extraction Report Language) is released by Larry Wall.</font></p></div></td></tr>
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Mickey
http://Opengenome.net/index.php?title=History_of_Bioinformatics&diff=29336&oldid=prev
Mickey at 05:10, 17 May 2009
2009-05-17T05:10:26Z
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<a href="http://Opengenome.net/index.php?title=History_of_Bioinformatics&diff=29336&oldid=8840">Show changes</a>
Mickey
http://Opengenome.net/index.php?title=History_of_Bioinformatics&diff=8840&oldid=prev
210.218.222.82 at 09:43, 13 March 2006
2006-03-13T09:43:37Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 09:43, 13 March 2006</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" color="#cc0000" size="4"><strong>1859:</strong></font><font face="Times New Roman" size="4"> </font><font face="Times New Roman" size="3"><strong>Charles Darwin, Cambridge, UK, publishes </strong></font><em><font face="Times New Roman" size="3"><strong>Th</strong></font></em><font face="Times New Roman" size="3"><strong>e O</strong></font><em><font face="Times New Roman" size="3"><strong>rigin of Species</strong></font></em><font face="Times New Roman" size="3"><strong>, vastly strengthening the adaptationist hypothesis.</strong></font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" color="#cc0000" size="4"><strong>1859:</strong></font><font face="Times New Roman" size="4"> </font><font face="Times New Roman" size="3"><strong>Charles Darwin, Cambridge, UK, publishes </strong></font><em><font face="Times New Roman" size="3"><strong>Th</strong></font></em><font face="Times New Roman" size="3"><strong>e O</strong></font><em><font face="Times New Roman" size="3"><strong>rigin of Species</strong></font></em><font face="Times New Roman" size="3"><strong>, vastly strengthening the adaptationist hypothesis.</strong></font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman" size="4">1864:</font></span></strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman"> Ernst Haeckel (H&auml;ckel) outlines the essential elements of modern zoological classification</font></span></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman" size="4">1864:</font></span></strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman"> Ernst Haeckel (H&auml;ckel) outlines the essential elements of modern zoological classification</font></span></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><span lang="EN-GB" style="FONT-FAMILY: 'Times New Roman'; mso-ascii-font-family: " <del class="diffchange diffchange-inline">times</del>="" <del class="diffchange diffchange-inline">new</del>=""><strong><font face="Times New Roman" color="#cc3300" size="4">1865:</font><font face="Times New Roman" size="3"> </font></strong></span><font face="Times New Roman" size="3">Gregory Mendel (1823-1884), Austria,&nbsp;&nbsp;<img height="44" alt="img1.gif" src="http://bio.cc/Bioinformatics/img1.gif" width="52" border="0" /> established the genetic inheritance. The theoretical study of genetics. </font><em><font face="Times New Roman">Experiments in Plant Hybridisation</font></em><font face="Times New Roman">. Cambridge, MA: Harvard University Press. His work, in German, was first published in 1865 in the </font><em><font face="Times New Roman">Proceedings of the Br&uuml;nn Society for Natural History</font></em><font face="Times New Roman">, Br&uuml;nn, Austria (</font><font face="Times New Roman">Hewlett, 1998</font><font face="Times New Roman">). It was ignored for a generation.</font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p><span lang="EN-GB" style="FONT-FAMILY: 'Times New Roman'; mso-ascii-font-family: " <ins class="diffchange diffchange-inline">new</ins>="" <ins class="diffchange diffchange-inline">times</ins>=""><strong><font face="Times New Roman" color="#cc3300" size="4">1865:</font><font face="Times New Roman" size="3"> </font></strong></span><font face="Times New Roman" size="3">Gregory Mendel (1823-1884), Austria,&nbsp;&nbsp;<img height="44" alt="img1.gif" src="http://bio.cc/Bioinformatics/img1.gif" width="52" border="0" /> established the genetic inheritance. The theoretical study of genetics. </font><em><font face="Times New Roman">Experiments in Plant Hybridisation</font></em><font face="Times New Roman">. Cambridge, MA: Harvard University Press. His work, in German, was first published in 1865 in the </font><em><font face="Times New Roman">Proceedings of the Br&uuml;nn Society for Natural History</font></em><font face="Times New Roman">, Br&uuml;nn, Austria (</font><font face="Times New Roman">Hewlett, 1998</font><font face="Times New Roman">). It was ignored for a generation.</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman,Helvetica" color="#cc0000" size="4"><strong>1868:</strong></font><font face="Times New Roman,Helvetica"><font color="#8000ff"> </font></font><font face="Times New Roman,Helvetica" color="#000000">Friedrich </font><font face="Times New Roman,Helvetica" color="#000000">Miescher</font><font face="Times New Roman,Helvetica" color="#000000"> </font><font face="Times New Roman,Helvetica">- discovery of </font><font face="Times New Roman,Helvetica" color="#000000"><strong>nuclein</strong></font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">found in cell nucleus, acidic, rich in <strong>PO<sub>4</sub></strong>,</font><font face="Times New Roman"> &nbsp;</font><font face="Times New Roman,Helvetica">lacks <strong>S </strong>(characteristic of protein).</font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">Now know this as <strong>nucleic acid</strong></font><font face="Times New Roman"> </font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman,Helvetica" color="#cc0000" size="4"><strong>1868:</strong></font><font face="Times New Roman,Helvetica"><font color="#8000ff"> </font></font><font face="Times New Roman,Helvetica" color="#000000">Friedrich </font><font face="Times New Roman,Helvetica" color="#000000">Miescher</font><font face="Times New Roman,Helvetica" color="#000000"> </font><font face="Times New Roman,Helvetica">- discovery of </font><font face="Times New Roman,Helvetica" color="#000000"><strong>nuclein</strong></font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">found in cell nucleus, acidic, rich in <strong>PO<sub>4</sub></strong>,</font><font face="Times New Roman"> &nbsp;</font><font face="Times New Roman,Helvetica">lacks <strong>S </strong>(characteristic of protein).</font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">Now know this as <strong>nucleic acid</strong></font><font face="Times New Roman"> </font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font face="Times New Roman" size="4"><strong>1902:</strong></font><font face="Times New Roman" size="3"> The chromosome theory of heredity is proposed by Sutton and Boveri, working independently. </font></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font face="Times New Roman" size="4"><strong>1902:</strong></font><font face="Times New Roman" size="3"> The chromosome theory of heredity is proposed by Sutton and Boveri, working independently. </font></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l122" >Line 122:</td>
<td colspan="2" class="diff-lineno">Line 122:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><font face="Times New Roman" size="4">1968:</font></strong> <font face="Times New Roman">Kimura, M. </font><strong><font face="Times New Roman">Evolutionary rate at the molecular level.</font></strong><font face="Times New Roman"> Nature 217 (1968) 624-626.</font></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><font face="Times New Roman" size="4">1968:</font></strong> <font face="Times New Roman">Kimura, M. </font><strong><font face="Times New Roman">Evolutionary rate at the molecular level.</font></strong><font face="Times New Roman"> Nature 217 (1968) 624-626.</font></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1969:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> The ARPANET is created by linking computers at Stanford, UCSB, The University of Utah and UCLA.</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1969:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> The ARPANET is created by linking computers at Stanford, UCSB, The University of Utah and UCLA.</font></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><strong><font face="Times New Roman" color="#cc3300" size="4">1970s</font><font face="Times New Roman" size="3">:</font></strong><font face="Times New Roman" size="3"> Fred Sanger, Cambridge UK, <del class="diffchange diffchange-inline">develop </del>deoxy DNA sequencing method.</font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><strong><font face="Times New Roman" color="#cc3300" size="4">1970s</font><font face="Times New Roman" size="3">:</font></strong><font face="Times New Roman" size="3"> Fred Sanger, Cambridge UK, <ins class="diffchange diffchange-inline">developed </ins>deoxy DNA sequencing method.</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><font face="Times New Roman" size="4">1970: </font></strong><font face="Times New Roman">Needleman SB, Wunsch CD. </font><strong><font face="Times New Roman">A general method applicable to the search for similarities in the amino acid sequence of two proteins.</font></strong><font face="Times New Roman"> J Mol Biol. 1970 Mar;48(3):443-53. </font></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><font face="Times New Roman" size="4">1970: </font></strong><font face="Times New Roman">Needleman SB, Wunsch CD. </font><strong><font face="Times New Roman">A general method applicable to the search for similarities in the amino acid sequence of two proteins.</font></strong><font face="Times New Roman"> J Mol Biol. 1970 Mar;48(3):443-53. </font></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" size="4"><strong>1970: </strong></font><font face="Times New Roman">Fitch, W. M. </font><strong><font face="Times New Roman">Distinguishing homologous from analogous proteins.</font></strong><font face="Times New Roman"> Syst Zool (1970) 19:99-113. </font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" size="4"><strong>1970: </strong></font><font face="Times New Roman">Fitch, W. M. </font><strong><font face="Times New Roman">Distinguishing homologous from analogous proteins.</font></strong><font face="Times New Roman"> Syst Zool (1970) 19:99-113. </font></p></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l144" >Line 144:</td>
<td colspan="2" class="diff-lineno">Line 144:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#cc3300" size="4"><strong>1975:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> E. M. Southern published the experimental details for the Southern Blot technique of specific sequences of DNA (<em>J. Mol. Biol.</em>, <strong>98</strong>: 503-517, 1975).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#cc3300" size="4"><strong>1975:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> E. M. Southern published the experimental details for the Southern Blot technique of specific sequences of DNA (<em>J. Mol. Biol.</em>, <strong>98</strong>: 503-517, 1975).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1976:</strong></font><font face="Times New Roman" size="4"><strong> </strong></font><font face="Times New Roman" size="3">&nbsp;</font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The Unix-To-Unix Copy Protocol (UUCP) is developed at Bell Labs. </font><font face="Times New Roman">Dr. Robert M. Metcalfe develops Ethernet, which allowed coaxial cable to move data extremely fast. This was a crucial component to the development of LANs. The packet satellite project went into practical use. SATNET, Atlantic packet Satellite network, was born. This network linked the United States with Europe.Surprisingly, it used INTELSAT satellites that were owned by a consortium of countries and not exclusively the United States government. UUCP (Unix-to-Unix CoPy) developed at AT&amp;T Bell Labs and distributed with UNIX one year later. The Department of Defense began to experiment with the TCP/IP protocol and soon decided to require it for use on ARPANET.</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1976:</strong></font><font face="Times New Roman" size="4"><strong> </strong></font><font face="Times New Roman" size="3">&nbsp;</font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The Unix-To-Unix Copy Protocol (UUCP) is developed at Bell Labs. </font><font face="Times New Roman">Dr. Robert M. Metcalfe develops Ethernet, which allowed coaxial cable to move data extremely fast. This was a crucial component to the development of LANs. The packet satellite project went into practical use. SATNET, Atlantic packet Satellite network, was born. This network linked the United States with Europe.Surprisingly, it used INTELSAT satellites that were owned by a consortium of countries and not exclusively the United States government. UUCP (Unix-to-Unix CoPy) developed at AT&amp;T Bell Labs and distributed with UNIX one year later. The Department of Defense began to experiment with the TCP/IP protocol and soon decided to require it for use on ARPANET.</font></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" size="4"><<del class="diffchange diffchange-inline">strong</del>>1977<del class="diffchange diffchange-inline">: </del></<del class="diffchange diffchange-inline">strong</del>></font><font face="Times New Roman">Staden programs. Roger Staden, MRC LMB, Cambridge, UK</font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p<ins class="diffchange diffchange-inline">><strong</ins>><font face="Times New Roman" size="4"><<ins class="diffchange diffchange-inline">font color="#993300"</ins>>1977</<ins class="diffchange diffchange-inline">font</ins>><ins class="diffchange diffchange-inline">: </ins></font><font face="Times New Roman<ins class="diffchange diffchange-inline">" size="3</ins>">Staden programs<ins class="diffchange diffchange-inline">. DNA sequence analysis software. Published in NAR</ins>. Roger Staden, MRC<ins class="diffchange diffchange-inline">, </ins>LMB, Cambridge, UK</font<ins class="diffchange diffchange-inline">></strong</ins>></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1977:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> The full description of the Brookhaven PDB (http://www.pdb.bnl.gov) is published (Bernstein, F.C.; Koetzle, T.F.; Williams, G.J.B.; Meyer, E.F.; Brice, M.D.; Rodgers, J.R.; Kennard, O.; Shimanouchi, T.; Tasumi, M.J.; <em>J. Mol. Biol.</em>, <strong>1977</strong>, <em>112</em>:, 535).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1977:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> The full description of the Brookhaven PDB (http://www.pdb.bnl.gov) is published (Bernstein, F.C.; Koetzle, T.F.; Williams, G.J.B.; Meyer, E.F.; Brice, M.D.; Rodgers, J.R.; Kennard, O.; Shimanouchi, T.; Tasumi, M.J.; <em>J. Mol. Biol.</em>, <strong>1977</strong>, <em>112</em>:, 535).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><font face="Times New Roman" size="4">1977:</font><font face="Times New Roman"> </font></strong><font face="Times New Roman">Procedures were developed for rapidly sequencing long sections of DNA. </font></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><font face="Times New Roman" size="4">1977:</font><font face="Times New Roman"> </font></strong><font face="Times New Roman">Procedures were developed for rapidly sequencing long sections of DNA. </font></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l152" >Line 152:</td>
<td colspan="2" class="diff-lineno">Line 152:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1980:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> W&uuml;thrich et. al. publish paper detailing the use of multi-dimensional NMR for protein structure determination (Kumar, A.; Ernst, R.R.; W&uuml;thrich, K.; <em>Biochem. Biophys. Res. Comm.</em>, <strong>1980</strong>, <em>95</em>:, 1).</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#000000" size="4"><strong>1980:</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3"> W&uuml;thrich et. al. publish paper detailing the use of multi-dimensional NMR for protein structure determination (Kumar, A.; Ernst, R.R.; W&uuml;thrich, K.; <em>Biochem. Biophys. Res. Comm.</em>, <strong>1980</strong>, <em>95</em>:, 1).</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1981:</strong></font><font face="Times New Roman" size="3"> &nbsp;</font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The Smith-Waterman algorithm for sequence alignment is published. </font><font face="Times New Roman">Smith TF, Waterman MS. </font><strong><font face="Times New Roman">Identification of common molecular subsequences.</font></strong><font face="Times New Roman"> J Mol Biol. 1981 Mar 25;147(1):195-7. </font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman" size="4"><strong>1981:</strong></font><font face="Times New Roman" size="3"> &nbsp;</font><font face="Times New Roman,Sans Serif" color="#000000" size="3">The Smith-Waterman algorithm for sequence alignment is published. </font><font face="Times New Roman">Smith TF, Waterman MS. </font><strong><font face="Times New Roman">Identification of common molecular subsequences.</font></strong><font face="Times New Roman"> J Mol Biol. 1981 Mar 25;147(1):195-7. </font></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" size="4"><strong>1981: </strong></font><font face="Times New Roman" size="3">Sequence motif Russell Doolittle.</font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" size="4"><strong>1981: </strong></font><font face="Times New Roman" size="3">Sequence motif<ins class="diffchange diffchange-inline">, </ins>Russell Doolittle.</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#cc0000" size="4"><strong>1981</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">: IBM introduces its Personal Computer to the market.</font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p align="left"><font face="Times New Roman,Sans Serif" color="#cc0000" size="4"><strong>1981</strong></font><font face="Times New Roman,Sans Serif" color="#000000" size="3">: IBM introduces its Personal Computer to the market.</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font face="Times New Roman" size="4">1981:</font><font face="Times New Roman"> Felsenstein, J. </font><strong><font face="Times New Roman">Evolutionary Trees from DNA-Sequences - a Maximum-Likelihood Approach.</font></strong><font face="Times New Roman"> J. Mol. Evol. (1981) 17:368-376. (hardcopy available</font></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font face="Times New Roman" size="4">1981:</font><font face="Times New Roman"> Felsenstein, J. </font><strong><font face="Times New Roman">Evolutionary Trees from DNA-Sequences - a Maximum-Likelihood Approach.</font></strong><font face="Times New Roman"> J. Mol. Evol. (1981) 17:368-376. (hardcopy available</font></div></td></tr>
</table>
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2006-03-06T06:49:37Z
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211.211.234.134 at 15:45, 14 January 2006
2006-01-14T15:45:37Z
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<table class="diff diff-contentalign-left" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:45, 14 January 2006</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l6" >Line 6:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>             <td width="758"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>             <td width="758"></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>             <p align="left"><strong><font face="Times New Roman" size="6">History of <del class="diffchange diffchange-inline"><a href="http://bio.cc/</del>Bioinformatics<del class="diffchange diffchange-inline">/">Bioinformatics</a></del></font></strong></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>             <p align="left"><strong><font face="Times New Roman" size="6">History of Bioinformatics</font></strong></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>             </td></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>             </td></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>         </tr></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>         </tr></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l89" >Line 89:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" color="#cc0000" size="4"><strong>1859:</strong></font><font face="Times New Roman" size="4"> </font><font face="Times New Roman" size="3"><strong>Charles Darwin, Cambridge, UK, publishes </strong></font><em><font face="Times New Roman" size="3"><strong>Th</strong></font></em><font face="Times New Roman" size="3"><strong>e O</strong></font><em><font face="Times New Roman" size="3"><strong>rigin of Species</strong></font></em><font face="Times New Roman" size="3"><strong>, vastly strengthening the adaptationist hypothesis.</strong></font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman" color="#cc0000" size="4"><strong>1859:</strong></font><font face="Times New Roman" size="4"> </font><font face="Times New Roman" size="3"><strong>Charles Darwin, Cambridge, UK, publishes </strong></font><em><font face="Times New Roman" size="3"><strong>Th</strong></font></em><font face="Times New Roman" size="3"><strong>e O</strong></font><em><font face="Times New Roman" size="3"><strong>rigin of Species</strong></font></em><font face="Times New Roman" size="3"><strong>, vastly strengthening the adaptationist hypothesis.</strong></font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman" size="4">1864:</font></span></strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman"> Ernst Haeckel (H&auml;ckel) outlines the essential elements of modern zoological classification</font></span></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman" size="4">1864:</font></span></strong><span style="FONT-FAMILY: Arial"><font face="Times New Roman"> Ernst Haeckel (H&auml;ckel) outlines the essential elements of modern zoological classification</font></span></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><span lang="EN-GB" style="FONT-FAMILY: 'Times New Roman'; mso-ascii-font-family: " <del class="diffchange diffchange-inline">times</del>="" <del class="diffchange diffchange-inline">new</del>=""><strong><font face="Times New Roman" color="#cc3300" size="4">1865:</font><font face="Times New Roman" size="3"> </font></strong></span><font face="Times New Roman" size="3">Gregory Mendel (1823-1884), Austria,&nbsp;&nbsp;<img height="44" alt="img1.gif" src="http://bio.cc/Bioinformatics/img1.gif" width="52" border="0" /> established the genetic inheritance. The theoretical study of genetics. </font><em><font face="Times New Roman">Experiments in Plant Hybridisation</font></em><font face="Times New Roman">. Cambridge, MA: Harvard University Press. His work, in German, was first published in 1865 in the </font><em><font face="Times New Roman">Proceedings of the Br&uuml;nn Society for Natural History</font></em><font face="Times New Roman">, Br&uuml;nn, Austria (</font><a href="http://bio.cc/Bioinformatics/history_of_bioinformatics.html#Hewlett"><font face="Times New Roman">Hewlett, 1998</font></a><font face="Times New Roman">). It was ignored for a generation.</font></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p><span lang="EN-GB" style="FONT-FAMILY: 'Times New Roman'; mso-ascii-font-family: " <ins class="diffchange diffchange-inline">new</ins>="" <ins class="diffchange diffchange-inline">times</ins>=""><strong><font face="Times New Roman" color="#cc3300" size="4">1865:</font><font face="Times New Roman" size="3"> </font></strong></span><font face="Times New Roman" size="3">Gregory Mendel (1823-1884), Austria,&nbsp;&nbsp;<img height="44" alt="img1.gif" src="http://bio.cc/Bioinformatics/img1.gif" width="52" border="0" /> established the genetic inheritance. The theoretical study of genetics. </font><em><font face="Times New Roman">Experiments in Plant Hybridisation</font></em><font face="Times New Roman">. Cambridge, MA: Harvard University Press. His work, in German, was first published in 1865 in the </font><em><font face="Times New Roman">Proceedings of the Br&uuml;nn Society for Natural History</font></em><font face="Times New Roman">, Br&uuml;nn, Austria (</font><a href="http://bio.cc/Bioinformatics/history_of_bioinformatics.html#Hewlett"><font face="Times New Roman">Hewlett, 1998</font></a><font face="Times New Roman">). It was ignored for a generation.</font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman,Helvetica" color="#cc0000" size="4"><strong>1868:</strong></font><font face="Times New Roman,Helvetica"><font color="#8000ff"> </font></font><font face="Times New Roman,Helvetica" color="#000000">Friedrich </font><a href="http://biopeople.net/Biologists/Friedrich_Miescher"><font face="Times New Roman,Helvetica" color="#000000">Miescher</font></a><font face="Times New Roman,Helvetica" color="#000000"> </font><font face="Times New Roman,Helvetica">- discovery of </font><font face="Times New Roman,Helvetica" color="#000000"><strong>nuclein</strong></font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">found in cell nucleus, acidic, rich in <strong>PO<sub>4</sub></strong>,</font><font face="Times New Roman"> &nbsp;</font><font face="Times New Roman,Helvetica">lacks <strong>S </strong>(characteristic of protein).</font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">Now know this as <strong>nucleic acid</strong></font><font face="Times New Roman"> </font></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><font face="Times New Roman,Helvetica" color="#cc0000" size="4"><strong>1868:</strong></font><font face="Times New Roman,Helvetica"><font color="#8000ff"> </font></font><font face="Times New Roman,Helvetica" color="#000000">Friedrich </font><a href="http://biopeople.net/Biologists/Friedrich_Miescher"><font face="Times New Roman,Helvetica" color="#000000">Miescher</font></a><font face="Times New Roman,Helvetica" color="#000000"> </font><font face="Times New Roman,Helvetica">- discovery of </font><font face="Times New Roman,Helvetica" color="#000000"><strong>nuclein</strong></font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">found in cell nucleus, acidic, rich in <strong>PO<sub>4</sub></strong>,</font><font face="Times New Roman"> &nbsp;</font><font face="Times New Roman,Helvetica">lacks <strong>S </strong>(characteristic of protein).</font><font face="Times New Roman"> </font><font face="Times New Roman,Helvetica">Now know this as <strong>nucleic acid</strong></font><font face="Times New Roman"> </font></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font face="Times New Roman" size="4"><strong>1902:</strong></font><font face="Times New Roman" size="3"> The chromosome theory of heredity is proposed by Sutton and Boveri, working independently. </font></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font face="Times New Roman" size="4"><strong>1902:</strong></font><font face="Times New Roman" size="3"> The chromosome theory of heredity is proposed by Sutton and Boveri, working independently. </font></div></td></tr>
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211.211.234.134
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211.211.234.134 at 15:45, 14 January 2006
2006-01-14T15:45:15Z
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