Bioinformatics - Revision history

WikiSysop at 02:16, 23 November 2010

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WikiSysop at 01:40, 10 April 2008

2008-04-10T01:40:49Z

WikiSysop at 01:39, 10 April 2008

2008-04-10T01:39:29Z

WikiSysop at 03:29, 28 February 2008

2008-02-28T03:29:05Z

WikiSysop: Protected "Bioinformatics" [edit=sysop:move=sysop]

2008-02-21T23:41:43Z

Protected "Bioinformatics" [edit=sysop:move=sysop]

WikiSysop at 23:41, 21 February 2008

2008-02-21T23:41:35Z

BorolSitro: liraceloutr

2008-02-19T18:23:36Z

liraceloutr

BorolSitro: ouricp

2008-02-12T09:03:02Z

ouricp

WikiSysop at 00:38, 14 January 2008

2008-01-14T00:38:54Z

VarpaSpasg: corelrelvaro

2008-01-11T10:42:29Z

corelrelvaro

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 </ul>
 <p>&nbsp;</p>
-<h2><span class="mw-headline">Software tools</span></h2>
+<p><span class="mw-headline"><font size="5">Software tools</font></span></p>
 <p>First generation bioinformatics tools consisted of applications, usually with a text-based interface, which performed a specific task well. The computational biology tool best-known among biologists is probably BLAST, an algorithm for searching large databases of protein or DNA sequences. The NCBI provides a popular web-based implementation that searches their massive sequence databases. Also fairly early on, due to the amassing of sequence and annotation data, keyword search engines which were able to resolve gene and protein synonyms were important. Computer scripting languages such as Perl (thanks to its regular expressions handling facilities) and Python are often used to interface with biological databases and parse output from bioinformatics programs written in languages such as C or C++. Communities of bioinformatics programmers have set up free open source bioinformatics projects to develop and distribute the tools and modules they produce.</p>
 <p>As the data sources expanded and diversified, both in content and geography, bioinformatic meta search engines, such as Sequence profiling tools, emerged to help find relevant information from several databases. These meta search engines might index data from a local server or even from a panel of third party services.</p>
 <p>More recently, SOAP-based interfaces have been developed for a wide variety of bioinformatics applications allowing an application running on one computer in one part of the world to use algorithms, data and computing resources on servers in other parts of the world. A large availability of these SOAP-based bioinformatics web services, along with the open source bioinformatics collections, lead to the next generation of bioinformatics tools: the integrated bioinformatics platform. These tools range from a collection of standalone tools with a common data format under a single, slick standalone or web-based interface, to integrative and extensible bioinformatics workflow development environments.</p>
 <p>&nbsp;</p>
-<h2><span class="mw-headline">See also</span></h2>
+<p><span class="mw-headline"><font size="5">See also</font></span></p>
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 <p>&nbsp;</p>
-<h2><span class="mw-headline">References</span></h2>
+<p><span class="mw-headline"><font size="5">References</font></span></p>
 <ul>
      <li>Aluru, Srinivas, ed. <em>Handbook of Computational Molecular Biology</em>. Chapman &amp; Hall/Crc, 2006. <a class="internal" href="http://en.wikipedia.org/w/index.php?title=Special:Booksources&amp;isbn=1584884061"><font color="#0066cc">ISBN 1584884061</font></a> (Chapman &amp; Hall/Crc Computer and Information Science Series) </li>
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-<h2><span class="mw-headline">External links</span></h2>
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      <li>
      <ul>
          <li><a class="external text" title="http://bioinformatics.org/" rel="nofollow" href="http://bioinformatics.org/"><font color="#0066cc">Bioinformatics Organization (Bioinformatics.Org): The Open-Access Institute</font></a> </li>
          <li><a class="external text" title="http://www.embnet.org/" rel="nofollow" href="http://www.embnet.org/"><font color="#0066cc">EMBnet</font></a> </li>

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-<p><strong>Bioinformatics</strong> and <strong>[[computational biology]]</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
+<p><strong>Bioinformatics</strong>&nbsp;involves the use of techniques including applied mathematics, informatics, statistics, computer science,&nbsp;chemistry, and biochemistry to solve biological problems. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
 <p>&nbsp;</p>
-<h2><span class="mw-headline">Introduction</span></h2>
+<p><span class="mw-headline"><font size="5">Introduction</font></span></p>
 <p>The terms <em>bioinformatics</em> and <em>computational biology</em> are often used interchangeably. However <em>bioinformatics</em> more properly refers to the creation and advancement of algorithms, computational and statistical techniques, and theory to solve formal and practical problems inspired from the management and analysis of biological data. <em>Computational biology,</em> on the other hand, refers to hypothesis-driven investigation of a specific biological problem using computers, carried out with experimental or simulated data, with the primary goal of discovery and the advancement of biological knowledge. Put more simply, bioinformatics is concerned with the information while computational biology is concerned with the hypotheses. A similar distinction is made by National Institutes of Health in their working definitions of Bioinformatics and Computational Biology, where it is further emphasized that there is a tight coupling of developments and knowledge between the more hypothesis-driven research in computational biology and technique-driven research in bioinformatics.</p>
 <p>A common thread in projects in bioinformatics and computational biology is the use of mathematical tools to extract useful information from data produced by high-throughput biological techniques such as genome sequencing. A representative problem in bioinformatics is the assembly of high-quality genome sequences from fragmentary &quot;shotgun&quot; DNA sequencing. Other common problems include the study of gene regulation using data from microarrays or mass spectrometry.</p>
 <p>&nbsp;</p>
-<h2><span class="mw-headline">Major research areas</span></h2>
+<p><span class="mw-headline"><font size="5">Major research areas</font></span></p>
 <p>&nbsp;</p>
 <h3><span class="mw-headline">Sequence analysis</span></h3>

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-<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
+<p><strong>Bioinformatics</strong> and <strong>[[computational biology]]</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
 <p>&nbsp;</p>
 <h2><span class="mw-headline">Introduction</span></h2>

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−	~~mondom~~
	<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>		<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
	<p> </p>		<p> </p>

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	mondom		mondom
	<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>		<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>

← Older revision	Revision as of 23:41, 21 February 2008
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← Older revision		Revision as of 09:03, 12 February 2008
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		+	mondom
	<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>		<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
	<p> </p>		<p> </p>

← Older revision		Revision as of 00:38, 14 January 2008
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−	~~chilab~~
	<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>		<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>
	<p> </p>		<p> </p>

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	chilab		chilab
	<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>		<p><strong>Bioinformatics</strong> and <strong>computational biology</strong> involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.</p>