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치료시스템(repair system) - Revision history
2026-06-09T20:16:14Z
Revision history for this page on the wiki
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http://Opengenome.net/index.php?title=%EC%B9%98%EB%A3%8C%EC%8B%9C%EC%8A%A4%ED%85%9C(repair_system)&diff=2083&oldid=prev
Yslee at 07:13, 17 January 2006
2006-01-17T07:13:44Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 07:13, 17 January 2006</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l32" >Line 32:</td>
<td colspan="2" class="diff-lineno">Line 32:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. &nbsp;</font></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. &nbsp;</font></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><strong><font face="Arial">2. 두개의 끝이 일정하게 절단된 경우</font></strong></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><strong><font face="Arial">2. 두개의 끝이 일정하게 절단된 경우</font></strong></span></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">두개의 끝이 일정하게 절단된 경우에 절단이 안된 밑의 나선을 주형으로 삼아 중합효소가 DNA를 복제하게 된다. </font></span></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial"><ins class="diffchange diffchange-inline">밑의 그림과 같이 </ins>두개의 끝이 일정하게 절단된 경우에 절단이 안된 밑의 나선을 주형으로 삼아 중합효소가 DNA를 복제하게 된다. </font></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;<!--StartFragment--> </p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;<!--StartFragment--> </p></div></td></tr>
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Yslee
http://Opengenome.net/index.php?title=%EC%B9%98%EB%A3%8C%EC%8B%9C%EC%8A%A4%ED%85%9C(repair_system)&diff=2082&oldid=prev
Yslee at 07:13, 17 January 2006
2006-01-17T07:13:25Z
<p></p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 07:13, 17 January 2006</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l32" >Line 32:</td>
<td colspan="2" class="diff-lineno">Line 32:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. &nbsp;</font></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. &nbsp;</font></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><strong><font face="Arial">2. 두개의 끝이 일정하게 절단된 경우</font></strong></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><strong><font face="Arial">2. 두개의 끝이 일정하게 절단된 경우</font></strong></span></p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">두개의 끝이 일정하게 절단된 <del class="diffchange diffchange-inline">경우에는 </del></font></span></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">두개의 끝이 일정하게 절단된 <ins class="diffchange diffchange-inline">경우에 절단이 안된 밑의 나선을 주형으로 삼아 중합효소가 DNA를 복제하게 된다. </ins></font></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;<!--StartFragment--> </p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;<!--StartFragment--> </p></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><img style="WIDTH: 320px; HEIGHT: 112px" height="123" src="file:///C:/DOCUME~1/선영/LOCALS~1/Temp/UNI000003dc29d7.gif" width="341" border="0" <del class="diffchange diffchange-inline">alt</del>="" <del class="diffchange diffchange-inline">/</del>></span></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><img style="WIDTH: 320px; HEIGHT: 112px" height="123<ins class="diffchange diffchange-inline">" alt="</ins>" src="file:///C:/DOCUME~1/선영/LOCALS~1/Temp/UNI000003dc29d7.gif" width="341" border="0" <ins class="diffchange diffchange-inline">/></span></p></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><p class="HStyle0"><span style</ins>="<ins class="diffchange diffchange-inline">FONT-FAMILY: &quot;한컴바탕&quot;</ins>"></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div></td></tr>
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Yslee
http://Opengenome.net/index.php?title=%EC%B9%98%EB%A3%8C%EC%8B%9C%EC%8A%A4%ED%85%9C(repair_system)&diff=2081&oldid=prev
Yslee at 07:12, 17 January 2006
2006-01-17T07:12:14Z
<p></p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<col class="diff-marker" />
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 07:12, 17 January 2006</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5" >Line 5:</td>
<td colspan="2" class="diff-lineno">Line 5:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;직접 잘못된 염기를 절단하여 올바르게 삽입하는 방법을 일컫는다. 대표적인 예로는 자외선으로 인하여 이중체를 형성한 T염기를 고치는 방법이 있다. 자외선을 받으면 연속하는 T염기가 서로 이중체를 형성하게 된다. 이때 가시광선을 받아 활성화가된 광분해 효소가 이중체를 형성한 부분을 절단하여 올바르게 염기결합을 하게 해준다.</p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;직접 잘못된 염기를 절단하여 올바르게 삽입하는 방법을 일컫는다. 대표적인 예로는 자외선으로 인하여 이중체를 형성한 T염기를 고치는 방법이 있다. 자외선을 받으면 연속하는 T염기가 서로 이중체를 형성하게 된다. 이때 가시광선을 받아 활성화가된 광분해 효소가 이중체를 형성한 부분을 절단하여 올바르게 염기결합을 하게 해준다.</p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul dir="ltr" style="MARGIN-RIGHT: 0px"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul dir="ltr" style="MARGIN-RIGHT: 0px"></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong>염기를 절단후&nbsp;교체 (base excision and replacement)</strong></li></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong>염기를 절단후&nbsp;교체 (base excision and replacement)</strong> </li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.&nbsp;염기 절단수복(base excision repair)</strong> </p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.&nbsp;염기 절단수복(base excision repair)</strong> </p></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l17" >Line 17:</td>
<td colspan="2" class="diff-lineno">Line 17:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong>복제후 수복시스템(postreplication repair)</strong></li></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong>복제후 수복시스템(postreplication repair)</strong> </li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23" >Line 23:</td>
<td colspan="2" class="diff-lineno">Line 23:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul dir="ltr"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul dir="ltr"></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong>두개의 strand가 절단이 된 경우</strong></li></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong>두개의 strand가 절단이 된 경우</strong> </li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><strong>1.끝 부분이 일정하지 않게 절단된 경우</strong>&nbsp;<!--StartFragment--> </p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><strong>1.끝 부분이 일정하지 않게 절단된 경우</strong>&nbsp;<!--StartFragment--> </p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><img style="WIDTH: 293px; HEIGHT: 43px" height="82" src="file:///C:/DOCUME~1/선영/LOCALS~1/Temp/UNI000003dc29d2.gif" width="339" border="0<del class="diffchange diffchange-inline">" alt="</del>" /></span></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><img style="WIDTH: 293px; HEIGHT: 43px" height="82<ins class="diffchange diffchange-inline">" alt="</ins>" src="file:///C:/DOCUME~1/선영/LOCALS~1/Temp/UNI000003dc29d2.gif" width="339" border="0" /></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. &nbsp;</font></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. &nbsp;</font></span></p></div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l34" >Line 34:</td>
<td colspan="2" class="diff-lineno">Line 34:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">두개의 끝이 일정하게 절단된 경우에는 </font></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">두개의 끝이 일정하게 절단된 경우에는 </font></span></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;</p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;<ins class="diffchange diffchange-inline"><!--StartFragment--> </p></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><img style="WIDTH: 320px; HEIGHT: 112px" height="123" src="file:///C:/DOCUME~1/선영/LOCALS~1/Temp/UNI000003dc29d7.gif" width="341" border="0" alt="" /></span></ins></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div></td></tr>
</table>
Yslee
http://Opengenome.net/index.php?title=%EC%B9%98%EB%A3%8C%EC%8B%9C%EC%8A%A4%ED%85%9C(repair_system)&diff=2080&oldid=prev
Yslee at 07:04, 17 January 2006
2006-01-17T07:04:58Z
<p></p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 07:04, 17 January 2006</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><!--StartFragment-->생체내에&nbsp;돌연변이된&nbsp;부분들을&nbsp;효소들을 이용하여&nbsp;원래의 모습으로 되돌리는 시스템을 일컫는다. </p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p><!--StartFragment-->생체내에&nbsp;돌연변이된&nbsp;부분들을&nbsp;효소들을 이용하여&nbsp;원래의 모습으로 되돌리는 시스템을 일컫는다. </p></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><ul dir="ltr" style="MARGIN-RIGHT: 0px"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">    <li><strong>직접반전 (direct reversal)</strong> </li></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ul></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><p>&nbsp;직접 잘못된 염기를 절단하여 올바르게 삽입하는 방법을 일컫는다. 대표적인 예로는 자외선으로 인하여 이중체를 형성한 T염기를 고치는 방법이 있다. 자외선을 받으면 연속하는 T염기가 서로 이중체를 형성하게 된다. 이때 가시광선을 받아 활성화가된 광분해 효소가 이중체를 형성한 부분을 절단하여 올바르게 염기결합을 하게 해준다.</p></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><ul dir="ltr" style="MARGIN-RIGHT: 0px"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">    <li><strong>염기를 절단후&nbsp;교체 (base excision and replacement)</strong></li></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ul></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.&nbsp;염기 절단수복(base excision repair)</strong> </p></ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><del class="diffchange diffchange-inline"><strong>1</del>.<del class="diffchange diffchange-inline">직접반전 (direct reversal)</strong> </del></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p><ins class="diffchange diffchange-inline">염기와 당의 결합을 glycosylase로 절단을 한다. 그렇게 되면 염기가 존재하지 않은 AP부분이 존재하게 되는데 이 부분을 인지한 AP 내부제한효소가 이 부분을 포함한 근처의 당 인산결합을 일정 양만큼 절단하게 된다. 절단된 부분을 중합효소로 다시 DNA를 합성한후 양 끝 부분을 결합효소로 붙여주면&nbsp;된다</ins>.</p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;<del class="diffchange diffchange-inline">직접 잘못된 염기를 절단하여 올바르게 삽입하는 방법을 일컫는다. 대표적인 예로는 자외선으로 인하여 이중체를 형성한 T염기를 고치는 방법이 있다. 자외선을 받으면 연속하는 T염기가 서로 이중체를 형성하게 된다. 이때 가시광선을 받아 활성화가된 광분해 효소가 이중체를 형성한 부분을 절단하여 올바르게 염기결합을 하게 해준다.</del></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;</p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><strong><del class="diffchange diffchange-inline">2. 염기를 절단후</del>&nbsp;<del class="diffchange diffchange-inline">교체 </del>(<del class="diffchange diffchange-inline">base </del>excision <del class="diffchange diffchange-inline">and replacement</del>)</strong></p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p><strong>&nbsp;<ins class="diffchange diffchange-inline">2. 뉴클레오티드 절단 수복 </ins>(<ins class="diffchange diffchange-inline">nucleotide </ins>excision <ins class="diffchange diffchange-inline">repair</ins>)</strong><ins class="diffchange diffchange-inline"></p></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><p>뉴클레오티드를 직접 절단하는 방법으로 관여하는 효소는 urvA,B,C이다. 변이가 된 부분을 포함한 일정 양 만큼의 &nbsp;뉴클레오티드를 urvA,B,C로 절단을 한후에 중합효소로 다시 DNA를 삽입하는 방법이다. </ins></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></blockquote></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><ul></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong><del class="diffchange diffchange-inline">염기 절단수복</del>(<del class="diffchange diffchange-inline">base excision </del>repair)</strong></li></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>     <li><strong><ins class="diffchange diffchange-inline">복제후 수복시스템</ins>(<ins class="diffchange diffchange-inline">postreplication </ins>repair)<ins class="diffchange diffchange-inline"></strong></li></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"></ul></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><p>DNA중합효소는 상당히 정교한 장치이다. 이것은 DNA를 새로 합성하면서 잘못된 DNA가 삽입된 경우에 바로 고칠수 있는 능력을 가지고 있다. 그러나 만약에&nbsp;이 중합효소가 잘못된 부분을 인지하지 못했을 경우에&nbsp;이용되는 방법이다.&nbsp;주형이 되는 부분은 염기 A에 메틸레이션이 되어 있어서 새로 복제되는 strand와 쉽게 구분이 될수 있게&nbsp; 되어 있다. 만약 새로 합성된 strand에 잘못된 염기가 첨가가 된다면 이 주형을 토대로 다시 새로운 염기를 합성하게 되는데 이 방법을 복제 후 수복 시스템이라고 한다. </p></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"></blockquote></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><ul dir="ltr"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">    <li><strong>두개의 strand가 절단이 된 경우</ins></strong></li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></ul></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p><del class="diffchange diffchange-inline">염기와 당의 결합을 glycosylase로 절단을 한다. 그렇게 되면 염기가 존재하지 않은 AP부분이 존재하게 되는데 이 부분을 인지한 AP 내부제한효소가 이 부분을 포함한 근처의 당 인산결합을 일정 양만큼 절단하게 된다</del>. 절단된 <del class="diffchange diffchange-inline">부분을 중합효소로 다시 DNA를 합성한후 양 끝 부분을 결합효소로 붙여주면</del>&nbsp;<del class="diffchange diffchange-inline">된다</del>.</p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"></ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;</p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p><ins class="diffchange diffchange-inline"><strong>1</ins>.<ins class="diffchange diffchange-inline">끝 부분이 일정하지 않게 </ins>절단된 <ins class="diffchange diffchange-inline">경우</strong></ins>&nbsp;<ins class="diffchange diffchange-inline"><!--StartFragment--> </p></ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><p>&<del class="diffchange diffchange-inline">nbsp</del>;</p></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"></blockquote></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><img style="WIDTH: 293px; HEIGHT: 43px" height="82" src="file:///C:/DOCUME~1/선영/LOCALS~1/Temp/UNI000003dc29d2</ins>.<ins class="diffchange diffchange-inline">gif" width="339" border="0" alt="" /></span></ins></p<ins class="diffchange diffchange-inline">></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><blockquote dir="ltr" style="MARGIN-RIGHT: 0px"</ins>></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p <ins class="diffchange diffchange-inline">class="HStyle0"</ins>><ins class="diffchange diffchange-inline"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><font face="Arial">이 그림과 같이 두개의 나선의 끝이 일정하지 않게 절단이 되었을떄에 KU70과 KU80이 두개의 끝을 일정하게 만들어 준 후&nbsp;두 나선을 붙여준다. </ins>&nbsp;<ins class="diffchange diffchange-inline"></font></span></p></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"><strong><font face="Arial">2. 두개의 끝이 일정하게 절단된 경우</font></strong></span></ins></p></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><p <ins class="diffchange diffchange-inline">class="HStyle0"</ins>><ins class="diffchange diffchange-inline"><span style="FONT-FAMILY: </ins>&<ins class="diffchange diffchange-inline">quot;한컴바탕&quot</ins>;<ins class="diffchange diffchange-inline">"><font face="Arial">두개의 끝이 일정하게 절단된 경우에는 </font></span></ins></p<ins class="diffchange diffchange-inline">></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline"></blockquote</ins>></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;</p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p>&nbsp;</p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div></td></tr>
</table>
Yslee
http://Opengenome.net/index.php?title=%EC%B9%98%EB%A3%8C%EC%8B%9C%EC%8A%A4%ED%85%9C(repair_system)&diff=2079&oldid=prev
Yslee at 06:44, 17 January 2006
2006-01-17T06:44:15Z
<p></p>
<p><b>New page</b></p><div><p><!--StartFragment-->생체내에&nbsp;돌연변이된&nbsp;부분들을&nbsp;효소들을 이용하여&nbsp;원래의 모습으로 되돌리는 시스템을 일컫는다. </p><br />
<blockquote dir="ltr" style="MARGIN-RIGHT: 0px"><br />
<p><strong>1.직접반전 (direct reversal)</strong> </p><br />
</blockquote><br />
<p>&nbsp;직접 잘못된 염기를 절단하여 올바르게 삽입하는 방법을 일컫는다. 대표적인 예로는 자외선으로 인하여 이중체를 형성한 T염기를 고치는 방법이 있다. 자외선을 받으면 연속하는 T염기가 서로 이중체를 형성하게 된다. 이때 가시광선을 받아 활성화가된 광분해 효소가 이중체를 형성한 부분을 절단하여 올바르게 염기결합을 하게 해준다.</p><br />
<blockquote dir="ltr" style="MARGIN-RIGHT: 0px"><br />
<p><strong>2. 염기를 절단후&nbsp;교체 (base excision and replacement)</strong></p><br />
</blockquote><br />
<ul><br />
<li><strong>염기 절단수복(base excision repair)</strong></li><br />
</ul><br />
<p>염기와 당의 결합을 glycosylase로 절단을 한다. 그렇게 되면 염기가 존재하지 않은 AP부분이 존재하게 되는데 이 부분을 인지한 AP 내부제한효소가 이 부분을 포함한 근처의 당 인산결합을 일정 양만큼 절단하게 된다. 절단된 부분을 중합효소로 다시 DNA를 합성한후 양 끝 부분을 결합효소로 붙여주면&nbsp;된다.</p><br />
<p>&nbsp;</p><br />
<p>&nbsp;</p><br />
<p>&nbsp;</p><br />
<p class="HStyle0"><span style="FONT-FAMILY: &quot;한컴바탕&quot;"></span></p></div>
Yslee