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<a href="http://www.biocarta.com/pathfiles/h_ghrelinPathway.gif">http://www.biocarta.com/pathfiles/h_ghrelinPathway.gif</a><br /> <br /> The somatotropic axis. 뇌하수체로부터 growth hormone(GH)의 분해와 합성은 Hypothalamic hormones GH-releasing hormone(GHRH)와 Somatostatin(SPIF)에 의해서 조절이 되는데, 이것은 혈액의 GH와 insulin과 유사한 growth factor-I(IGF-I)의 농도로부터 feedback(dashed lines)에 의해서 다시 조절되어진다.<br /> <br /> <table style="WIDTH: 595px; HEIGHT: 163px" cellspacing="1" cellpadding="1" width="595" summary="" border="1"> <tbody> <tr> <td>&nbsp;</td> <td>&nbsp;</td> </tr> <tr> <td> <p align="center">GHRH</p> </td> <td> <p align="center">Hypothalamus</p> </td> </tr> <tr> <td> <p align="center">GHRH</p> </td> <td> <p align="center">Brain</p> </td> </tr> <tr> <td> <p align="center">IGFBP-3</p> </td> <td> <p align="center">IGF1</p> </td> </tr> <tr> <td> <p align="center">IGFBP-3</p> </td> <td> <p align="center">ALS</p> </td> </tr> <tr> <td> <p align="center">IGFBP-3</p> </td> <td> <p align="center">IGF-1</p> </td> </tr> <tr> <td> <p align="center">GHRL</p> </td> <td> <p align="center">Brain</p> </td> </tr> <tr> <td> <p align="center">IGF1</p> </td> <td> <p align="center">IGRBP-3</p> </td> </tr> </tbody> </table>

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