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생정보학책

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[http://bvio.ngic.re.kr/Biowiki-2.0/index.php/%EC%83%9D%EC%A0%95%EB%B3%B4%ED%95%99%EC%B1%85 생정보학책]<br /><br />
<p align="center"><strong><font size="4">생정보학책 (BioInformatics Book)</font></strong></p>
<p align="center"><strong>박종화 (Jong Bhak)</strong> </p>
<p align="center">BiOcentre: Biological Information Objects </p>
<p align="center">http://bio.cc/</p>
<p align="center">j@bio.cc 2005/9/10 </p>
<p><strong>내용 Contents</strong></p>
<p>[[생정보학책 머리말]] Preface </p>
<p>[[생정보학의 이름 번역에 대해서]] [[Translating bioinformatics]] </p>
<p>[[생정보학 기본원칙과 철학]] [[Bioinformatics First principles]] </p>
<p>[[생정보학의 역사]] [[Brief history of Bioinformatics]] </p>
<ul>
<li>[[생정보학의 현재]] </li>
<li>[[생정보학의 미래]] </li>
</ul>
<p>[[생정보학이란 무엇인가?]] [[What is Bioinformatics?]] </p>
<ul>
<li>[[데이타와 정보란 무엇인가?]] [[What are data and information?]] </li>
<li>[[생정보학의 세가지 핵심 요소들]]<br /></li>
</ul>
<p>[[생정보학자란 어떤것인가?]] [[Bioinformatist]] </p>
<p>[[생정보학에서의 체학(Omics)와 네트워크생물학]] (망생물학: Network biology) </p>
<p>[[단백질이란]]: 생명현상의 가장 핵심적인 정보처리 단위 [[What is a protein?]] </p>
<ul>
<li>[[아미노산]]: 단백질내의 정보처리 스위치와 구조적 단위 [[Amino acids]]: basic information unit of proteins </li>
<li>[[생정보학의 큰 영역 여섯가지]] [[Six large meta-omics in bioinformatics]].
<ul>
<li>[[유전체학]] :&nbsp; Genomics </li>
<li>[[전사체학]] : Transcriptomics </li>
<li>[[단백체학]] : Proteomics </li>
<li>[[작용체학]]&nbsp;([[상호작용체]]):&nbsp;Interactomics&nbsp;&nbsp; </li>
<li>[[기능체학]] : Functomics </li>
<li>[[문헌체학]] :&nbsp; Textomics </li>
</ul>
</li>
<li>[[생정보학의 큰 정보체 여섯가지]]
<ul>
<li>[[서열체]] : Sequenceome, Sequence information </li>
<li>[[구조체]] : Structome, Structure information </li>
<li>[[발현체]] :&nbsp;Expressome, Expressed concentration information </li>
<li>[[신호체]] (신호 회로체)&nbsp;:&nbsp;Signalome,&nbsp;Signal information&nbsp; </li>
<li>[[조절체]] : Regulome, Regulation information&nbsp; </li>
<li>[[망사체]] :&nbsp; Networkome, Network information </li>
</ul>
</li>
</ul>
<p>&nbsp;</p>
<p><strong>단백질와 다른분자들의 표현법 Representing proteins and other molecules</strong> </p>
<p>복잡성이 낮은 서열들 Low complexity sequences </p>
<p>단백질 서열의 친족성 Sequence homology </p>
<p>친족성기반 구조 모델만들기 Structure modelling by homology </p>
<p>실꿰기 모델 (단백질 구조인식) Threading (Fold recognition) </p>
<p>막바로 단백질 구조 예측하기 Ab initio protein structure prediction </p>
<p>기초적 친족성 찾기 알고리듬 Basic homology search algorithms </p>
<p>[[Dynamic Programming search algorithm]] </p>
<p>[[서열 파일포멧]] Sequence file formats </p>
<p>[[복수정열 서열 표현]] (Multiple sequences representation) </p>
<p>[[아미노산 친족성 행렬]] Amino acid homology matrix </p>
<p>[[파일포맷 전환]] (Parsing file format) </p>
<p>[[단백질의 성질 표현하기]] Representing special characteristics of proteins (sequences) </p>
<ul>
<li>Hydrophobicity (Hydropathy plot) </li>
<li>Secondary structure of proteins </li>
<li>Accessibility of protein structure. </li>
<li>Topology of protein structures. </li>
<li>Flexibility of protein structures. </li>
</ul>
<p>DNA: the biogrammar of cellular language </p>
<p>[[생정보학 전산기술]] Computing Technology</p>
<p>[[데이타베이스]] Database </p>
<p>[[알고리듬]] Algorithm </p>
<p>[[체학에 따른 생정보학의 분야]] </p>
<ul>
<li>[[서열체학]] (Sequenceomics) </li>
<li>[[구조체학]] (Structomics) </li>
<li>[[발현체학]] (Expressomics) </li>
<li>[[상호작용체학]] (Interactomics) </li>
<li>[[기능체학]] (Functomics) </li>
<li>[[문헌체학]] (Textomics) </li>
</ul>
<p>[[생정보학책 참고문헌]] (References)</p>
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